| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the digoxigenin-5640 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AMOTL2 | angiomotin like 2 |
| ANKRD55 | ankyrin repeat domain 55 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| AVPI1 | arginine vasopressin-induced 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| C4BPA | complement component 4 binding protein, alpha |
| CA4 | carbonic anhydrase IV |
| CD47 | CD47 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CLDN1 | claudin 1 |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CTGF | connective tissue growth factor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DLX2 | distal-less homeobox 2 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EDN1 | endothelin 1 |
| EED | embryonic ectoderm development |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EPHA2 | EPH receptor A2 |
| EWSR1 | EWS RNA-binding protein 1 |
| FAM46A | family with sequence similarity 46, member A |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL2 | FOS-like antigen 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GRB7 | growth factor receptor-bound protein 7 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HBP1 | HMG-box transcription factor 1 |
| HIC2 | hypermethylated in cancer 2 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXC13 | homeobox C13 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| KLHL20 | kelch-like family member 20 |
| KLHL24 | kelch-like family member 24 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MCL1 | myeloid cell leukemia 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED6 | mediator complex subunit 6 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP160 | nucleoporin 160kDa |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OVOL1 | ovo-like zinc finger 1 |
| PGLYRP1 | peptidoglycan recognition protein 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRSS22 | protease, serine, 22 |
| RARA | retinoic acid receptor, alpha |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SERTAD3 | SERTA domain containing 3 |
| SIK1 | salt-inducible kinase 1 |
| SKIL | SKI-like proto-oncogene |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMAD7 | SMAD family member 7 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX3 | syntaxin 3 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TGFB2 | transforming growth factor, beta 2 |
| THBS1 | thrombospondin 1 |
| TXNIP | thioredoxin interacting protein |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| YTHDC1 | YTH domain containing 1 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF143 | zinc finger protein 143 |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANKRD46 | ankyrin repeat domain 46 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASTN2 | astrotactin 2 |
| BBX | bobby sox homolog (Drosophila) |
| BMP4 | bone morphogenetic protein 4 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CANT1 | calcium activated nucleotidase 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| DEAF1 | DEAF1 transcription factor |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DUS2 | dihydrouridine synthase 2 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ERCC5 | excision repair cross-complementation group 5 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FANCF | Fanconi anemia, complementation group F |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GPALPP1 | GPALPP motifs containing 1 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIAA0125 | KIAA0125 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LIAS | lipoic acid synthetase |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| MCRS1 | microspherule protein 1 |
| MKKS | McKusick-Kaufman syndrome |
| MRPS31 | mitochondrial ribosomal protein S31 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| ORC3 | origin recognition complex, subunit 3 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PAAF1 | proteasomal ATPase-associated factor 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 |
| PCDHB3 | protocadherin beta 3 |
| PER3 | period circadian clock 3 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTK6 | protein tyrosine kinase 6 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 |
| SYT17 | synaptotagmin XVII |
| TBC1D31 | TBC1 domain family, member 31 |
| TFB1M | transcription factor B1, mitochondrial |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRIM27 | tripartite motif containing 27 |
| TRIM45 | tripartite motif containing 45 |
| TRIM5 | tripartite motif containing 5 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UNC119 | unc-119 homolog (C. elegans) |
| WDR3 | WD repeat domain 3 |
| WDR37 | WD repeat domain 37 |
| WDR5B | WD repeat domain 5B |
| XBP1 | X-box binding protein 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZFP69B | ZFP69 zinc finger protein B |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF23 | zinc finger protein 23 |
| ZNF239 | zinc finger protein 239 |
| ZNF248 | zinc finger protein 248 |
| ZNF302 | zinc finger protein 302 |
| ZNF696 | zinc finger protein 696 |
| ZNF74 | zinc finger protein 74 |
| ZNF778 | zinc finger protein 778 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
