| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the digoxin-2423 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRB3 | adrenoceptor beta 3 |
| AREG | amphiregulin |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ATF3 | activating transcription factor 3 |
| ATF7IP | activating transcription factor 7 interacting protein |
| BCL3 | B-cell CLL/lymphoma 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTG2 | BTG family, member 2 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C18ORF25 | chromosome 18 open reading frame 25 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CD83 | CD83 molecule |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CLEC4A | C-type lectin domain family 4, member A |
| CREM | cAMP responsive element modulator |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| EED | embryonic ectoderm development |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EPHA4 | EPH receptor A4 |
| FCAR | Fc fragment of IgA receptor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| G0S2 | G0/G1 switch 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| IER3 | immediate early response 3 |
| IGHM | immunoglobulin heavy constant mu |
| IL1A | interleukin 1, alpha |
| IL1B | interleukin 1, beta |
| IL24 | interleukin 24 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MORN1 | MORN repeat containing 1 |
| MTF1 | metal-regulatory transcription factor 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NPC1 | Niemann-Pick disease, type C1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OLFM1 | olfactomedin 1 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PLP1 | proteolipid protein 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTX3 | pentraxin 3, long |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS2 | regulator of G-protein signaling 2 |
| RND1 | Rho family GTPase 1 |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| RUNX1 | runt-related transcription factor 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC6A7 | solute carrier family 6 (neurotransmitter transporter), member 7 |
| SMC4 | structural maintenance of chromosomes 4 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| THBS1 | thrombospondin 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TM2D1 | TM2 domain containing 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TOB2 | transducer of ERBB2, 2 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIM38 | tripartite motif containing 38 |
| TSPAN13 | tetraspanin 13 |
| TUBB2A | tubulin, beta 2A class IIa |
| TXNIP | thioredoxin interacting protein |
| UBXN1 | UBX domain protein 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADM | adrenomedullin |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BBS10 | Bardet-Biedl syndrome 10 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CALHM2 | calcium homeostasis modulator 2 |
| CBR1 | carbonyl reductase 1 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCNE2 | cyclin E2 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DCLRE1A | DNA cross-link repair 1A |
| DENND2D | DENN/MADD domain containing 2D |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DUSP6 | dual specificity phosphatase 6 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GPR63 | G protein-coupled receptor 63 |
| ICT1 | immature colon carcinoma transcript 1 |
| IFT81 | intraflagellar transport 81 |
| JRKL | JRK-like |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KLF11 | Kruppel-like factor 11 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCRS1 | microspherule protein 1 |
| METTL8 | methyltransferase like 8 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MKKS | McKusick-Kaufman syndrome |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MSRB1 | methionine sulfoxide reductase B1 |
| MXD3 | MAX dimerization protein 3 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAGK | N-acetylglucosamine kinase |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NFE2 | nuclear factor, erythroid 2 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PEX12 | peroxisomal biogenesis factor 12 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PNMA1 | paraneoplastic Ma antigen 1 |
| POGK | pogo transposable element with KRAB domain |
| PRDM13 | PR domain containing 13 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRR3 | proline rich 3 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SAMD9 | sterile alpha motif domain containing 9 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC35A5 | solute carrier family 35, member A5 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK16 | serine/threonine kinase 16 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TM2D3 | TM2 domain containing 3 |
| TMEM177 | transmembrane protein 177 |
| TMEM243 | transmembrane protein 243, mitochondrial |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| UBL4A | ubiquitin-like 4A |
| WDR3 | WD repeat domain 3 |
| WDR5B | WD repeat domain 5B |
| XPA | xeroderma pigmentosum, complementation group A |
| ZNF23 | zinc finger protein 23 |
| ZNF250 | zinc finger protein 250 |
| ZNF302 | zinc finger protein 302 |
| ZNF32 | zinc finger protein 32 |
| ZNF33B | zinc finger protein 33B |
| ZNF354A | zinc finger protein 354A |
| ZNF536 | zinc finger protein 536 |
| ZNF623 | zinc finger protein 623 |
| ZNF7 | zinc finger protein 7 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZW10 | zw10 kinetochore protein |
