| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the digoxin-3283 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADM | adrenomedullin |
| AMOTL2 | angiomotin like 2 |
| ATF3 | activating transcription factor 3 |
| AVPI1 | arginine vasopressin-induced 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CLDN1 | claudin 1 |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DRD1 | dopamine receptor D1 |
| DSC2 | desmocollin 2 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EDN1 | endothelin 1 |
| EED | embryonic ectoderm development |
| EFNA1 | ephrin-A1 |
| EFNB2 | ephrin-B2 |
| EGR1 | early growth response 1 |
| ENSA | endosulfine alpha |
| EPHA2 | EPH receptor A2 |
| EPHA4 | EPH receptor A4 |
| FAM46A | family with sequence similarity 46, member A |
| FANCA | Fanconi anemia, complementation group A |
| FASTKD2 | FAST kinase domains 2 |
| FLJ11292 | |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HAMP | hepcidin antimicrobial peptide |
| HBP1 | HMG-box transcription factor 1 |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST2H2BE | histone cluster 2, H2be |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXC13 | homeobox C13 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IL6 | interleukin 6 |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| KLHL25 | kelch-like family member 25 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LDLR | low density lipoprotein receptor |
| LINS | lines homolog (Drosophila) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MCL1 | myeloid cell leukemia 1 |
| MFAP3 | microfibrillar-associated protein 3 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIB | nuclear factor I/B |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OVOL1 | ovo-like zinc finger 1 |
| PCDH9 | protocadherin 9 |
| RARG | retinoic acid receptor, gamma |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM5 | RNA binding motif protein 5 |
| RGS16 | regulator of G-protein signaling 16 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RND3 | Rho family GTPase 3 |
| RRBP1 | ribosome binding protein 1 |
| SERTAD3 | SERTA domain containing 3 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SIK1 | salt-inducible kinase 1 |
| SKIL | SKI-like proto-oncogene |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| STX3 | syntaxin 3 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TGFB2 | transforming growth factor, beta 2 |
| THBS1 | thrombospondin 1 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TXNIP | thioredoxin interacting protein |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| WDR33 | WD repeat domain 33 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFX | zinc finger protein, X-linked |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF654 | zinc finger protein 654 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| ANKRD46 | ankyrin repeat domain 46 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BBX | bobby sox homolog (Drosophila) |
| BMP4 | bone morphogenetic protein 4 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC15 | coiled-coil domain containing 15 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CPOX | coproporphyrinogen oxidase |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGR3 | early growth response 3 |
| EHD3 | EH-domain containing 3 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ERCC5 | excision repair cross-complementation group 5 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FANCF | Fanconi anemia, complementation group F |
| FANCL | Fanconi anemia, complementation group L |
| FJX1 | four jointed box 1 (Drosophila) |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GPR19 | G protein-coupled receptor 19 |
| HPS5 | Hermansky-Pudlak syndrome 5 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| KIZ | kizuna centrosomal protein |
| KRCC1 | lysine-rich coiled-coil 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC61 | leucine rich repeat containing 61 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCRS1 | microspherule protein 1 |
| MKKS | McKusick-Kaufman syndrome |
| MRPS31 | mitochondrial ribosomal protein S31 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NELFE | negative elongation factor complex member E |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| ORC3 | origin recognition complex, subunit 3 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PALB2 | partner and localizer of BRCA2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PRR3 | proline rich 3 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETD1B | SET domain containing 1B |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 |
| SURF2 | surfeit 2 |
| TBC1D31 | TBC1 domain family, member 31 |
| TBCCD1 | TBCC domain containing 1 |
| TFB1M | transcription factor B1, mitochondrial |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM16 | tripartite motif containing 16 |
| TRIM27 | tripartite motif containing 27 |
| TRIM45 | tripartite motif containing 45 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog |
| WDR3 | WD repeat domain 3 |
| WDR5B | WD repeat domain 5B |
| XBP1 | X-box binding protein 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF184 | zinc finger protein 184 |
| ZNF23 | zinc finger protein 23 |
| ZNF239 | zinc finger protein 239 |
| ZNF248 | zinc finger protein 248 |
| ZNF250 | zinc finger protein 250 |
| ZNF302 | zinc finger protein 302 |
| ZNF32 | zinc finger protein 32 |
| ZNF33B | zinc finger protein 33B |
| ZNF544 | zinc finger protein 544 |
| ZNF573 | zinc finger protein 573 |
| ZNF623 | zinc finger protein 623 |
| ZW10 | zw10 kinetochore protein |
