| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the digoxin-6724 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADM | adrenomedullin |
| AFF4 | AF4/FMR2 family, member 4 |
| AMOTL2 | angiomotin like 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF3 | activating transcription factor 3 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTG2 | BTG family, member 2 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CCNL1 | cyclin L1 |
| CD83 | CD83 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN2AIP | CDKN2A interacting protein |
| CLK1 | CDC-like kinase 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CTH | cystathionine gamma-lyase |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLX2 | distal-less homeobox 2 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| ELL | elongation factor RNA polymerase II |
| FAM46C | family with sequence similarity 46, member C |
| FLCN | folliculin |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL2 | FOS-like antigen 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPR87 | G protein-coupled receptor 87 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4D | histone cluster 1, H4d |
| HIST3H2A | histone cluster 3, H2a |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLF2 | Kruppel-like factor 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL20 | kelch-like family member 20 |
| KLHL24 | kelch-like family member 24 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPC1 | paraspeckle component 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB30 | RAB30, member RAS oncogene family |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RHOB | ras homolog family member B |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| RUNX1 | runt-related transcription factor 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SFPQ | splicing factor proline/glutamine-rich |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC35F5 | solute carrier family 35, member F5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOCS3 | suppressor of cytokine signaling 3 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STK17B | serine/threonine kinase 17b |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TEX14 | testis expressed 14 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSC22D2 | TSC22 domain family, member 2 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| WSB1 | WD repeat and SOCS box containing 1 |
| YTHDC1 | YTH domain containing 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF136 | zinc finger protein 136 |
| ZNF335 | zinc finger protein 335 |
| ZNF586 | zinc finger protein 586 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANKRD36B | ankyrin repeat domain 36B |
| APOLD1 | apolipoprotein L domain containing 1 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CBR3 | carbonyl reductase 3 |
| CBX8 | chromobox homolog 8 |
| CCDC51 | coiled-coil domain containing 51 |
| CDC7 | cell division cycle 7 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| ECM1 | extracellular matrix protein 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EVPL | envoplakin |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FANCF | Fanconi anemia, complementation group F |
| FANCL | Fanconi anemia, complementation group L |
| FHOD1 | formin homology 2 domain containing 1 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| G0S2 | G0/G1 switch 2 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 |
| GOLGA5 | golgin A5 |
| HDAC7 | histone deacetylase 7 |
| HMGA2 | high mobility group AT-hook 2 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA11 | homeobox A11 |
| JRKL | JRK-like |
| KIAA1462 | KIAA1462 |
| KLF11 | Kruppel-like factor 11 |
| KLHL36 | kelch-like family member 36 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC100127972 | uncharacterized LOC100127972 |
| LOC100272216 | uncharacterized LOC100272216 |
| MANSC1 | MANSC domain containing 1 |
| MAP6D1 | MAP6 domain containing 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MXD3 | MAX dimerization protein 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| POGK | pogo transposable element with KRAB domain |
| PRMT7 | protein arginine methyltransferase 7 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBM15B | RNA binding motif protein 15B |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RGS19 | regulator of G-protein signaling 19 |
| RGS20 | regulator of G-protein signaling 20 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RIN2 | Ras and Rab interactor 2 |
| RNF25 | ring finger protein 25 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| RUFY2 | RUN and FYVE domain containing 2 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SACS | sacsin molecular chaperone |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SEPHS2 | selenophosphate synthetase 2 |
| SHROOM2 | shroom family member 2 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNPH | syntaphilin |
| SPATA7 | spermatogenesis associated 7 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYNC | syncoilin, intermediate filament protein |
| TDRD7 | tudor domain containing 7 |
| TIGD6 | tigger transposable element derived 6 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRIM16 | tripartite motif containing 16 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| VASH2 | vasohibin 2 |
| WDR5B | WD repeat domain 5B |
| XBP1 | X-box binding protein 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF232 | zinc finger protein 232 |
| ZNF248 | zinc finger protein 248 |
| ZNF365 | zinc finger protein 365 |
| ZNF415 | zinc finger protein 415 |
| ZNF529 | zinc finger protein 529 |
| ZNF667 | zinc finger protein 667 |
| ZNF668 | zinc finger protein 668 |
| ZNF862 | zinc finger protein 862 |
| ZW10 | zw10 kinetochore protein |
