dihydroergocristine-1745 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the dihydroergocristine-1745 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADARB1 adenosine deaminase, RNA-specific, B1
ADD3 adducin 3 (gamma)
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARL4C ADP-ribosylation factor-like 4C
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATXN2 ataxin 2
AXL AXL receptor tyrosine kinase
BAIAP2 BAI1-associated protein 2
BATF basic leucine zipper transcription factor, ATF-like
BEX1 brain expressed, X-linked 1
BIN1 bridging integrator 1
BMP6 bone morphogenetic protein 6
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CCDC40 coiled-coil domain containing 40
CCL20 chemokine (C-C motif) ligand 20
CD38 CD38 molecule
CD44 CD44 molecule (Indian blood group)
CD86 CD86 molecule
CDK16 cyclin-dependent kinase 16
CFLAR CASP8 and FADD-like apoptosis regulator
CHD3 chromodomain helicase DNA binding protein 3
CHN2 chimerin 2
CIITA class II, major histocompatibility complex, transactivator
COL4A2 collagen, type IV, alpha 2
CPD carboxypeptidase D
CPNE3 copine III
CREM cAMP responsive element modulator
CTNND1 catenin (cadherin-associated protein), delta 1
CTSB cathepsin B
DNAH17 dynein, axonemal, heavy chain 17
DOCK4 dedicator of cytokinesis 4
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GAB2 GRB2-associated binding protein 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GEM GTP binding protein overexpressed in skeletal muscle
GK glycerol kinase
GPR183 G protein-coupled receptor 183
GPSM2 G-protein signaling modulator 2
GUCA1B guanylate cyclase activator 1B (retina)
HIST1H2BD histone cluster 1, H2bd
HLA-DRA major histocompatibility complex, class II, DR alpha
HOMER1 homer scaffolding protein 1
IFI30 interferon, gamma-inducible protein 30
IL2RB interleukin 2 receptor, beta
ISG20 interferon stimulated exonuclease gene 20kDa
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KRT2 keratin 2, type II
KYNU kynureninase
LINC00312 long intergenic non-protein coding RNA 312
LXN latexin
MALT1 MALT1 paracaspase
MCAM melanoma cell adhesion molecule
MX2 MX dynamin-like GTPase 2
MXRA8 matrix-remodelling associated 8
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PECAM1 platelet/endothelial cell adhesion molecule 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLSCR1 phospholipid scramblase 1
POR P450 (cytochrome) oxidoreductase
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB31 RAB31, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
S1PR4 sphingosine-1-phosphate receptor 4
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SATB1 SATB homeobox 1
SDC2 syndecan 2
SGK1 serum/glucocorticoid regulated kinase 1
SH2D2A SH2 domain containing 2A
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SMOX spermine oxidase
SPTAN1 spectrin, alpha, non-erythrocytic 1
SYNGR2 synaptogyrin 2
TCTN1 tectonic family member 1
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TMEM194A transmembrane protein 194A
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
WIPI1 WD repeat domain, phosphoinositide interacting 1
WNK1 WNK lysine deficient protein kinase 1
ZFYVE16 zinc finger, FYVE domain containing 16
ZFYVE9 zinc finger, FYVE domain containing 9

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ADCK3 aarF domain containing kinase 3
ADRB2 adrenoceptor beta 2, surface
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
BATF3 basic leucine zipper transcription factor, ATF-like 3
BRIX1 BRX1, biogenesis of ribosomes
BYSL bystin-like
C11ORF68 chromosome 11 open reading frame 68
C3AR1 complement component 3a receptor 1
C5ORF28 chromosome 5 open reading frame 28
CA2 carbonic anhydrase II
CCDC86 coiled-coil domain containing 86
CCL2 chemokine (C-C motif) ligand 2
CD302 CD302 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTH cystathionine gamma-lyase
CTPS1 CTP synthase 1
DCPS decapping enzyme, scavenger
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
EBNA1BP2 EBNA1 binding protein 2
EFCAB2 EF-hand calcium binding domain 2
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENDOG endonuclease G
EXOSC5 exosome component 5
FAM136A family with sequence similarity 136, member A
FAM216A family with sequence similarity 216, member A
FAM222B family with sequence similarity 222, member B
FAR2 fatty acyl CoA reductase 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GLRX5 glutaredoxin 5
GSAP gamma-secretase activating protein
HEATR3 HEAT repeat containing 3
HIRA histone cell cycle regulator
HMBS hydroxymethylbilane synthase
HOPX HOP homeobox
HSPB1 heat shock 27kDa protein 1
IARS isoleucyl-tRNA synthetase
IFRD2 interferon-related developmental regulator 2
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIF21B kinesin family member 21B
MINA MYC induced nuclear antigen
MRPL12 mitochondrial ribosomal protein L12
MRPL4 mitochondrial ribosomal protein L4
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MYBBP1A MYB binding protein (P160) 1a
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCF1C neutrophil cytosolic factor 1C pseudogene
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NHP2 NHP2 ribonucleoprotein
NIP7 NIP7, nucleolar pre-rRNA processing protein
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOP14 NOP14 nucleolar protein
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
ORM1 orosomucoid 1
PFAS phosphoribosylformylglycinamidine synthase
PFDN2 prefoldin subunit 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POGLUT1 protein O-glucosyltransferase 1
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
PRDM13 PR domain containing 13
PSAT1 phosphoserine aminotransferase 1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PUS1 pseudouridylate synthase 1
PUS7 pseudouridylate synthase 7 (putative)
RPIA ribose 5-phosphate isomerase A
RPL39L ribosomal protein L39-like
RUVBL1 RuvB-like AAA ATPase 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SDHAF3 succinate dehydrogenase complex assembly factor 3
SEH1L SEH1-like (S. cerevisiae)
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SRM spermidine synthase
STRA13 stimulated by retinoic acid 13
TFB2M transcription factor B2, mitochondrial
TNF tumor necrosis factor
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
TTC27 tetratricopeptide repeat domain 27
TXLNA taxilin alpha
UNG uracil-DNA glycosylase
WDR12 WD repeat domain 12
WDR3 WD repeat domain 3
WDR43 WD repeat domain 43
XAF1 XIAP associated factor 1
YARS tyrosyl-tRNA synthetase
ZNF136 zinc finger protein 136
ZNF8 zinc finger protein 8