dihydroergocristine-2895 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the dihydroergocristine-2895 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADAP2 ArfGAP with dual PH domains 2
AHI1 Abelson helper integration site 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ANPEP alanyl (membrane) aminopeptidase
ARPIN actin-related protein 2/3 complex inhibitor
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATM ATM serine/threonine kinase
ATP10B ATPase, class V, type 10B
BDKRB2 bradykinin receptor B2
BMP1 bone morphogenetic protein 1
BMP6 bone morphogenetic protein 6
C17ORF59 chromosome 17 open reading frame 59
CALML5 calmodulin-like 5
CD48 CD48 molecule
CDO1 cysteine dioxygenase type 1
CGA glycoprotein hormones, alpha polypeptide
CIDEB cell death-inducing DFFA-like effector b
COL5A2 collagen, type V, alpha 2
DDIT4 DNA-damage-inducible transcript 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP4 dual specificity phosphatase 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FOXG1 forkhead box G1
GJA8 gap junction protein, alpha 8, 50kDa
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRIK5 glutamate receptor, ionotropic, kainate 5
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HFE hemochromatosis
HIF3A hypoxia inducible factor 3, alpha subunit
HIPK2 homeodomain interacting protein kinase 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPM heterogeneous nuclear ribonucleoprotein M
ICA1 islet cell autoantigen 1, 69kDa
IGFBP3 insulin-like growth factor binding protein 3
IL11 interleukin 11
IL23A interleukin 23, alpha subunit p19
IL4R interleukin 4 receptor
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
IPW imprinted in Prader-Willi syndrome (non-protein coding)
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL11 kelch-like family member 11
KLHL24 kelch-like family member 24
KLHL25 kelch-like family member 25
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAOB monoamine oxidase B
MAX MYC associated factor X
MED16 mediator complex subunit 16
MEF2D myocyte enhancer factor 2D
METTL7A methyltransferase like 7A
MINK1 misshapen-like kinase 1
MRPL41 mitochondrial ribosomal protein L41
MST1R macrophage stimulating 1 receptor
NCOR2 nuclear receptor corepressor 2
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NPC1 Niemann-Pick disease, type C1
NPFFR1 neuropeptide FF receptor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUMA1 nuclear mitotic apparatus protein 1
PDLIM5 PDZ and LIM domain 5
PLA2G3 phospholipase A2, group III
PRODH proline dehydrogenase (oxidase) 1
PSPH phosphoserine phosphatase
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNFT1 ring finger protein, transmembrane 1
RPL10 ribosomal protein L10
RSG1 REM2 and RAB-like small GTPase 1
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SCAPER S-phase cyclin A-associated protein in the ER
SDC2 syndecan 2
SEC24D SEC24 family member D
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SKIL SKI-like proto-oncogene
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPAG6 sperm associated antigen 6
SPRED2 sprouty-related, EVH1 domain containing 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STYK1 serine/threonine/tyrosine kinase 1
TAOK2 TAO kinase 2
TAPBP TAP binding protein (tapasin)
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
TM4SF1 transmembrane 4 L six family member 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
UBTD1 ubiquitin domain containing 1
USP34 ubiquitin specific peptidase 34
ZER1 zyg-11 related, cell cycle regulator
ZMYND8 zinc finger, MYND-type containing 8
ZNF528 zinc finger protein 528
ZNF652 zinc finger protein 652
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABLIM3 actin binding LIM protein family, member 3
ANXA2P3 annexin A2 pseudogene 3
ASAP1-IT1 ASAP1 intronic transcript 1
ATAD5 ATPase family, AAA domain containing 5
BMP10 bone morphogenetic protein 10
C17ORF70 chromosome 17 open reading frame 70
C19ORF73 chromosome 19 open reading frame 73
C1ORF159 chromosome 1 open reading frame 159
CARD8 caspase recruitment domain family, member 8
CD83 CD83 molecule
CDK20 cyclin-dependent kinase 20
CEP112 centrosomal protein 112kDa
CLCF1 cardiotrophin-like cytokine factor 1
CRY2 cryptochrome circadian clock 2
CTRL chymotrypsin-like
CXXC4 CXXC finger protein 4
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSCAM Down syndrome cell adhesion molecule
DTX4 deltex 4, E3 ubiquitin ligase
EDAR ectodysplasin A receptor
ERCC5 excision repair cross-complementation group 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETNK2 ethanolamine kinase 2
FAM110B family with sequence similarity 110, member B
FAM204A family with sequence similarity 204, member A
FBXO4 F-box protein 4
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FOXI1 forkhead box I1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GK2 glycerol kinase 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTA4 glutathione S-transferase alpha 4
GSTM2 glutathione S-transferase mu 2 (muscle)
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HOXC5 homeobox C5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT54 intraflagellar transport 54
IL22 interleukin 22
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LIME1 Lck interacting transmembrane adaptor 1
LOC390998 ribosomal protein L10 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MVP major vault protein
NME5 NME/NM23 family member 5
NPTX1 neuronal pentraxin I
ONECUT1 one cut homeobox 1
OTUD3 OTU deubiquitinase 3
PARD6A par-6 family cell polarity regulator alpha
PCDHA5 protocadherin alpha 5
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCD1 phospholipase C, delta 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
QSER1 glutamine and serine rich 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASL11B RAS-like, family 11, member B
RELN reelin
RHOH ras homolog family member H
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A2 S100 calcium binding protein A2
SECTM1 secreted and transmembrane 1
SGK2 serum/glucocorticoid regulated kinase 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D17 TBC1 domain family, member 17
TEX14 testis expressed 14
TLR2 toll-like receptor 2
TMEM132A transmembrane protein 132A
TSC22D4 TSC22 domain family, member 4
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWISTNB TWIST neighbor
TYRP1 tyrosinase-related protein 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR62 WD repeat domain 62
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XYLT2 xylosyltransferase II
ZFP37 ZFP37 zinc finger protein
ZNF137P zinc finger protein 137, pseudogene
ZNF442 zinc finger protein 442
ZNF532 zinc finger protein 532
ZNF573 zinc finger protein 573