dihydroergocristine-7275 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dihydroergocristine-7275 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
ALPK1 alpha-kinase 1
AMBRA1 autophagy/beclin-1 regulator 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
BAG4 BCL2-associated athanogene 4
BSPRY B-box and SPRY domain containing
BTD biotinidase
BTN3A1 butyrophilin, subfamily 3, member A1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCHCR1 coiled-coil alpha-helical rod protein 1
CCP110 centriolar coiled coil protein 110kDa
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP162 centrosomal protein 162kDa
CHM choroideremia (Rab escort protein 1)
CST1 cystatin SN
CTNND2 catenin (cadherin-associated protein), delta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYLD cylindromatosis (turban tumor syndrome)
DAGLA diacylglycerol lipase, alpha
DESI2 desumoylating isopeptidase 2
DPYS dihydropyrimidinase
DTX2 deltex 2, E3 ubiquitin ligase
DUSP8 dual specificity phosphatase 8
FES FES proto-oncogene, tyrosine kinase
FKBP8 FK506 binding protein 8, 38kDa
GLRB glycine receptor, beta
GLS glutaminase
GON4L gon-4-like (C. elegans)
GRK4 G protein-coupled receptor kinase 4
HAMP hepcidin antimicrobial peptide
HDGFRP3 hepatoma-derived growth factor, related protein 3
HPS1 Hermansky-Pudlak syndrome 1
IFI35 interferon-induced protein 35
IFIH1 interferon induced with helicase C domain 1
INO80B INO80 complex subunit B
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLHL20 kelch-like family member 20
LHX2 LIM homeobox 2
LIG4 ligase IV, DNA, ATP-dependent
MAGEH1 melanoma antigen family H1
MAP7 microtubule-associated protein 7
MB myoglobin
MBD1 methyl-CpG binding domain protein 1
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MOBP myelin-associated oligodendrocyte basic protein
MVP major vault protein
MX1 MX dynamin-like GTPase 1
MZF1 myeloid zinc finger 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NPFFR1 neuropeptide FF receptor 1
NRP1 neuropilin 1
NRXN3 neurexin 3
NTSR1 neurotensin receptor 1 (high affinity)
NUDCD3 NudC domain containing 3
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
PDGFRL platelet-derived growth factor receptor-like
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRF1 perforin 1 (pore forming protein)
RAD50 RAD50 homolog (S. cerevisiae)
RARG retinoic acid receptor, gamma
RBBP9 retinoblastoma binding protein 9
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RDX radixin
REEP2 receptor accessory protein 2
RPL10L ribosomal protein L10-like
RPL7 ribosomal protein L7
SC5D sterol-C5-desaturase
SEC14L4 SEC14-like 4 (S. cerevisiae)
SIRT3 sirtuin 3
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SP100 SP100 nuclear antigen
SPPL2B signal peptide peptidase like 2B
SPTAN1 spectrin, alpha, non-erythrocytic 1
TADA2A transcriptional adaptor 2A
TADA3 transcriptional adaptor 3
TBC1D19 TBC1 domain family, member 19
TMEM212 transmembrane protein 212
TMEM70 transmembrane protein 70
TRIM3 tripartite motif containing 3
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WNT1 wingless-type MMTV integration site family, member 1
WWOX WW domain containing oxidoreductase
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF44 zinc finger protein 44
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM15 ADAM metallopeptidase domain 15
ANXA10 annexin A10
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCAS3 breast carcinoma amplified sequence 3
BCL2L2 BCL2-like 2
BGLAP bone gamma-carboxyglutamate (gla) protein
C6ORF47 chromosome 6 open reading frame 47
CAPN15 calpain 15
CARD8 caspase recruitment domain family, member 8
CCDC101 coiled-coil domain containing 101
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC37L1 cell division cycle 37-like 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDC73 cell division cycle 73
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP72 centrosomal protein 72kDa
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CLUH clustered mitochondria (cluA/CLU1) homolog
COCH cochlin
CRYBB2P1 crystallin, beta B2 pseudogene 1
CXCL6 chemokine (C-X-C motif) ligand 6
DCAF10 DDB1 and CUL4 associated factor 10
DHRS11 dehydrogenase/reductase (SDR family) member 11
EHD3 EH-domain containing 3
FAM13B family with sequence similarity 13, member B
FAM160B2 family with sequence similarity 160, member B2
FOXC1 forkhead box C1
GPATCH1 G patch domain containing 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAUS6 HAUS augmin-like complex, subunit 6
HIRA histone cell cycle regulator
HIST1H2BI histone cluster 1, H2bi
HIST1H3G histone cluster 1, H3g
HLX H2.0-like homeobox
HOXA5 homeobox A5
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KIAA0232 KIAA0232
KIAA0556 KIAA0556
KIAA0753 KIAA0753
KLHL3 kelch-like family member 3
KRT4 keratin 4, type II
LPAR3 lysophosphatidic acid receptor 3
MBD5 methyl-CpG binding domain protein 5
MEIS1 Meis homeobox 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRPL52 mitochondrial ribosomal protein L52
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NABP2 nucleic acid binding protein 2
NAG18 NAG18 mRNA
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NRSN2 neurensin 2
NUPL1 nucleoporin like 1
NUPL2 nucleoporin like 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEX26 peroxisomal biogenesis factor 26
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PLSCR4 phospholipid scramblase 4
PORCN porcupine homolog (Drosophila)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKX protein kinase, X-linked
PROSER1 proline and serine rich 1
PTCD2 pentatricopeptide repeat domain 2
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAD9A RAD9 homolog A (S. pombe)
RASA2 RAS p21 protein activator 2
RBM6 RNA binding motif protein 6
RNF121 ring finger protein 121
RNF219 ring finger protein 219
RPL23AP32 ribosomal protein L23a pseudogene 32
SCML2 sex comb on midleg-like 2 (Drosophila)
SIAH2 siah E3 ubiquitin protein ligase 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SND1-IT1 SND1 intronic transcript 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMCC2 transmembrane and coiled-coil domain family 2
VWA1 von Willebrand factor A domain containing 1
WASF3 WAS protein family, member 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF230 zinc finger protein 230
ZNF696 zinc finger protein 696
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2