| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dihydroergotamine-1398 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ADD3 | adducin 3 (gamma) |
| ANXA1 | annexin A1 |
| ANXA2 | annexin A2 |
| AREG | amphiregulin |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARRB2 | arrestin, beta 2 |
| AXL | AXL receptor tyrosine kinase |
| BCL3 | B-cell CLL/lymphoma 3 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCNG2 | cyclin G2 |
| CD38 | CD38 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD86 | CD86 molecule |
| CENPE | centromere protein E, 312kDa |
| CHN2 | chimerin 2 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLEC2B | C-type lectin domain family 2, member B |
| CREB3 | cAMP responsive element binding protein 3 |
| CREM | cAMP responsive element modulator |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CSNK1D | casein kinase 1, delta |
| CTSB | cathepsin B |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK4 | dedicator of cytokinesis 4 |
| DUSP4 | dual specificity phosphatase 4 |
| FAM13A | family with sequence similarity 13, member A |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GAB2 | GRB2-associated binding protein 2 |
| GAS7 | growth arrest-specific 7 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GIMAP5 | GTPase, IMAP family member 5 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR183 | G protein-coupled receptor 183 |
| GPSM2 | G-protein signaling modulator 2 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BF | histone cluster 1, H2bf |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| IFI30 | interferon, gamma-inducible protein 30 |
| KLHL18 | kelch-like family member 18 |
| KYNU | kynureninase |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LPXN | leupaxin |
| MALT1 | MALT1 paracaspase |
| MCL1 | myeloid cell leukemia 1 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MX2 | MX dynamin-like GTPase 2 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLSCR1 | phospholipid scramblase 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POR | P450 (cytochrome) oxidoreductase |
| PPAP2A | phosphatidic acid phosphatase type 2A |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
| RAB31 | RAB31, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RGS2 | regulator of G-protein signaling 2 |
| RRBP1 | ribosome binding protein 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDC2 | syndecan 2 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC35E3 | solute carrier family 35, member E3 |
| SMOX | spermine oxidase |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STK19 | serine/threonine kinase 19 |
| THBS1 | thrombospondin 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRIM38 | tripartite motif containing 38 |
| VRK2 | vaccinia related kinase 2 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACTL6A | actin-like 6A |
| ADCK3 | aarF domain containing kinase 3 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAG2 | BCL2-associated athanogene 2 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| CA2 | carbonic anhydrase II |
| CBS | cystathionine-beta-synthase |
| CCDC86 | coiled-coil domain containing 86 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDK4 | cyclin-dependent kinase 4 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| CECR5 | cat eye syndrome chromosome region, candidate 5 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CISH | cytokine inducible SH2-containing protein |
| CTSG | cathepsin G |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DEAF1 | DEAF1 transcription factor |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| EBNA1BP2 | EBNA1 binding protein 2 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| ENOPH1 | enolase-phosphatase 1 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) |
| FAM216A | family with sequence similarity 216, member A |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IFRD2 | interferon-related developmental regulator 2 |
| IRF8 | interferon regulatory factor 8 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KIAA0020 | KIAA0020 |
| KIAA0930 | KIAA0930 |
| KIF21B | kinesin family member 21B |
| LAS1L | LAS1-like (S. cerevisiae) |
| MRPL3 | mitochondrial ribosomal protein L3 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MYBBP1A | MYB binding protein (P160) 1a |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NIPA2 | non imprinted in Prader-Willi/Angelman syndrome 2 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOL8 | nucleolar protein 8 |
| NUCB2 | nucleobindin 2 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCID2 | PCI domain containing 2 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PHGDH | phosphoglycerate dehydrogenase |
| PMM2 | phosphomannomutase 2 |
| PNPO | pyridoxamine 5'-phosphate oxidase |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PPAN | peter pan homolog (Drosophila) |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| PRDX4 | peroxiredoxin 4 |
| PRMT5 | protein arginine methyltransferase 5 |
| PRTN3 | proteinase 3 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PUS1 | pseudouridylate synthase 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RUVBL1 | RuvB-like AAA ATPase 1 |
| SCRIB | scribbled planar cell polarity protein |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SEH1L | SEH1-like (S. cerevisiae) |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| TCERG1 | transcription elongation regulator 1 |
| TFB2M | transcription factor B2, mitochondrial |
| TRIB3 | tribbles pseudokinase 3 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| UCK2 | uridine-cytidine kinase 2 |
| UNG | uracil-DNA glycosylase |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR12 | WD repeat domain 12 |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| XPOT | exportin, tRNA |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZNF146 | zinc finger protein 146 |
