| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the dihydroergotamine-4502 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C8B | complement component 8, beta polypeptide |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CD68 | CD68 molecule |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CEP41 | centrosomal protein 41kDa |
| CERS4 | ceramide synthase 4 |
| CLCA1 | chloride channel accessory 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLEC11A | C-type lectin domain family 11, member A |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| COL9A3 | collagen, type IX, alpha 3 |
| CORO2B | coronin, actin binding protein, 2B |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DMC1 | DNA meiotic recombinase 1 |
| ECE1 | endothelin converting enzyme 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EXOSC2 | exosome component 2 |
| FAM134B | family with sequence similarity 134, member B |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLP1R | glucagon-like peptide 1 receptor |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GSN-AS1 | GSN antisense RNA 1 |
| HHAT | hedgehog acyltransferase |
| HPX | hemopexin |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGHM | immunoglobulin heavy constant mu |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL1R2 | interleukin 1 receptor, type II |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KRT19P2 | keratin 19 pseudogene 2 |
| LDAH | lipid droplet associated hydrolase |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC17 | leucine rich repeat containing 17 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFAP3L | microfibrillar-associated protein 3-like |
| MMP25 | matrix metallopeptidase 25 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NPR2 | natriuretic peptide receptor 2 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NRXN3 | neurexin 3 |
| OLFM1 | olfactomedin 1 |
| OR7C1 | olfactory receptor, family 7, subfamily C, member 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAPPA2 | pappalysin 2 |
| PAX4 | paired box 4 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRKCDBP | protein kinase C, delta binding protein |
| PTCH1 | patched 1 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAB36 | RAB36, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| REC8 | REC8 meiotic recombination protein |
| RIN3 | Ras and Rab interactor 3 |
| ROPN1B | rhophilin associated tail protein 1B |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SERHL2 | serine hydrolase-like 2 |
| SFTPB | surfactant protein B |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC6A16 | solute carrier family 6, member 16 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STOML1 | stomatin (EPB72)-like 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBCD | tubulin folding cofactor D |
| TBX5 | T-box 5 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THTPA | thiamine triphosphatase |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRA | T cell receptor alpha locus |
| TRIM10 | tripartite motif containing 10 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| ZNF528 | zinc finger protein 528 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ANOS1 | anosmin 1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BBC3 | BCL2 binding component 3 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNL2 | cyclin L2 |
| CD101 | CD101 molecule |
| CDHR2 | cadherin-related family member 2 |
| CEP295 | centrosomal protein 295kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLDN8 | claudin 8 |
| CTSF | cathepsin F |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DIXDC1 | DIX domain containing 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO2 | F-box protein 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR176 | G protein-coupled receptor 176 |
| GTF2I | general transcription factor IIi |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIRA | histone cell cycle regulator |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA1 | homeobox A1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL17RA | interleukin 17 receptor A |
| IMPACT | impact RWD domain protein |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| LINS | lines homolog (Drosophila) |
| LMO7 | LIM domain 7 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| NABP1 | nucleic acid binding protein 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NEK11 | NIMA-related kinase 11 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OSMR | oncostatin M receptor |
| OTUD3 | OTU deubiquitinase 3 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE12 | phosphodiesterase 12 |
| PER3 | period circadian clock 3 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PKN1 | protein kinase N1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RAB5B | RAB5B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RECQL4 | RecQ protein-like 4 |
| RNF122 | ring finger protein 122 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SELL | selectin L |
| SH2D4A | SH2 domain containing 4A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SP1 | Sp1 transcription factor |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TMEM120B | transmembrane protein 120B |
| TMEM53 | transmembrane protein 53 |
| TNS2 | tensin 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC23 | tetratricopeptide repeat domain 23 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YY2 | YY2 transcription factor |
| ZNF134 | zinc finger protein 134 |
| ZNF286A | zinc finger protein 286A |
| ZNF324 | zinc finger protein 324 |
| ZNF442 | zinc finger protein 442 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF711 | zinc finger protein 711 |
| ZNF768 | zinc finger protein 768 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |