dihydroergotamine-mesylate Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

640 genes differentially expressed following the dihydroergotamine-mesylate small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CD180 CD180 molecule 6.73805
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 6.64694
PNLIPRP1 pancreatic lipase-related protein 1 6.1313
TUFM Tu translation elongation factor, mitochondrial 5.70883
EIF5 eukaryotic translation initiation factor 5 5.45645
RHEBP1 Ras-homolog enriched in brain pseudogene 1 5.42856
SGK1 serum/glucocorticoid regulated kinase 1 5.28118
OCRL oculocerebrorenal syndrome of Lowe 5.26711
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 5.25725
MEF2C myocyte enhancer factor 2C 5.21519
METTL9 methyltransferase like 9 5.13474
BEX4 brain expressed, X-linked 4 5.12729
MARCHF6 membrane associated ring-CH-type finger 6 5.12418
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 5.06355
FBXO9 F-box protein 9 4.98896
ASTN1 astrotactin 1 4.98809
TUBB6 tubulin, beta 6 class V 4.97711
PTK2B protein tyrosine kinase 2 beta 4.97533
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 4.94692
NTAN1 N-terminal asparagine amidase 4.90009
PRSS21 protease, serine, 21 (testisin) 4.84612
GPRC5D G protein-coupled receptor, class C, group 5, member D 4.82614
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 4.81465
RGS20 regulator of G-protein signaling 20 4.79767
CLPS colipase, pancreatic 4.79189
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 4.78781
NKX2-5 NK2 homeobox 5 4.77036
EHD3 EH-domain containing 3 4.7481
MSRB1 methionine sulfoxide reductase B1 4.73942
CEP170 centrosomal protein 170kDa 4.68116
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 4.64876
STX7 syntaxin 7 4.6185
TICAM1 toll-like receptor adaptor molecule 1 4.58306
CIAO1 cytosolic iron-sulfur assembly component 1 4.57607
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 4.5734
FAM20B family with sequence similarity 20, member B 4.54614
METTL7A methyltransferase like 7A 4.51616
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 4.50142
VANGL1 VANGL planar cell polarity protein 1 4.47945
TMED5 transmembrane emp24 protein transport domain containing 5 4.45161
BAIAP3 BAI1-associated protein 3 4.4034
NR2E1 nuclear receptor subfamily 2, group E, member 1 4.39035
CELA3A chymotrypsin-like elastase family, member 3A 4.38402
PLPPR4 phospholipid phosphatase related 4 4.37621
BTBD3 BTB (POZ) domain containing 3 4.3672
CXCR4 chemokine (C-X-C motif) receptor 4 4.35802
SHFL shiftless antiviral inhibitor of ribosomal frameshifting 4.35744
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 4.35434
BDNF brain-derived neurotrophic factor 4.33542
FAM131A family with sequence similarity 131, member A 4.32309
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 4.31518
IRF5 interferon regulatory factor 5 4.30457
NFE2 nuclear factor, erythroid 2 4.27407
LMO3 LIM domain only 3 (rhombotin-like 2) 4.26566
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 4.25711
RUNX1 runt-related transcription factor 1 4.24853
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 4.21614
CLDN15 claudin 15 4.18881
PNLIP pancreatic lipase 4.15262
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 4.11996
LGI1 leucine-rich, glioma inactivated 1 4.11361
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 4.09211
FCRL2 Fc receptor-like 2 4.08231
ETV1 ets variant 1 4.06623
TSEN34 TSEN34 tRNA splicing endonuclease subunit 4.06457
IVL involucrin 4.06137
SWAP70 SWAP switching B-cell complex 70kDa subunit 4.05061
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 4.04279
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 4.03687
ITGA7 integrin, alpha 7 4.00404
TOR1A torsin family 1, member A (torsin A) 3.99648
DOCK3 dedicator of cytokinesis 3 3.97762
HYAL4 hyaluronoglucosaminidase 4 3.97526
SYNGR1 synaptogyrin 1 3.96848
OSBPL11 oxysterol binding protein-like 11 3.93908
OR51E2 olfactory receptor, family 51, subfamily E, member 2 3.93367
FOXF2 forkhead box F2 3.9276
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 3.92241
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 3.91245
EPHB6 EPH receptor B6 3.88465
DDN dendrin 3.88411
UNC45A unc-45 homolog A (C. elegans) 3.86886
ATAD2B ATPase family, AAA domain containing 2B 3.8669
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 3.85595
MYH10 myosin, heavy chain 10, non-muscle 3.85032
GLI2 GLI family zinc finger 2 3.84477
SCNN1G sodium channel, non voltage gated 1 gamma subunit 3.83156
MAPK3 mitogen-activated protein kinase 3 3.8242
CTNNA2 catenin (cadherin-associated protein), alpha 2 3.82011
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 3.80887
CSK c-src tyrosine kinase 3.80815
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 3.80343
NPAS2 neuronal PAS domain protein 2 3.7942
RAB8A RAB8A, member RAS oncogene family 3.79387
CDX4 caudal type homeobox 4 3.79263
TFEC transcription factor EC 3.79049
ETNPPL ethanolamine-phosphate phospho-lyase 3.77319
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 3.76909
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 3.76845
ESPN espin 3.7644
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 3.7597
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 3.75851
FABP4 fatty acid binding protein 4, adipocyte 3.75656
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 3.75572
PARP12 poly (ADP-ribose) polymerase family, member 12 3.74678
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 3.73699
PRDM16 PR domain containing 16 3.7319
ANOS1 anosmin 1 3.71485
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 3.6992
MN1 meningioma (disrupted in balanced translocation) 1 3.68318
NT5C2 5'-nucleotidase, cytosolic II 3.6802
CTRB2 chymotrypsinogen B2 3.68011
CA5B carbonic anhydrase VB, mitochondrial 3.67642
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 3.67102
C1ORF216 chromosome 1 open reading frame 216 3.65343
EGR2 early growth response 2 3.64144
ADRB3 adrenoceptor beta 3 3.63914
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.6369
PCDHB1 protocadherin beta 1 3.63538
ALCAM activated leukocyte cell adhesion molecule 3.6337
SNAP25 synaptosomal-associated protein, 25kDa 3.63252
ECE2 endothelin converting enzyme 2 3.6156
PKLR pyruvate kinase, liver and RBC 3.59582
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 3.5887
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 3.58134
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 3.57717
CTSA cathepsin A 3.57116
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 3.5594
ZNF271P zinc finger protein 271, pseudogene 3.554
CRK v-crk avian sarcoma virus CT10 oncogene homolog 3.54948
CPA1 carboxypeptidase A1 (pancreatic) 3.54375
PNISR PNN-interacting serine/arginine-rich protein 3.53325
AVPR1A arginine vasopressin receptor 1A 3.52787
SPATA7 spermatogenesis associated 7 3.52729
KIF20A kinesin family member 20A 3.52045
IL36RN interleukin 36 receptor antagonist 3.51801
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.51654
SYN1 synapsin I 3.51255
JAKMIP2 janus kinase and microtubule interacting protein 2 3.51053
FGF3 fibroblast growth factor 3 3.50836
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 3.50803
MXI1 MAX interactor 1, dimerization protein 3.50303
G6PC2 glucose-6-phosphatase, catalytic, 2 3.49406
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 3.4864
CELA3B chymotrypsin-like elastase family, member 3B 3.4819
BRAF B-Raf proto-oncogene, serine/threonine kinase 3.47766
CORO1C coronin, actin binding protein, 1C 3.47683
FGF13 fibroblast growth factor 13 3.45318
ATP2A3 ATPase, Ca++ transporting, ubiquitous 3.45253
MSH2 mutS homolog 2 3.45224
PGLS 6-phosphogluconolactonase 3.45062
TYMP thymidine phosphorylase 3.44421
RSAD2 radical S-adenosyl methionine domain containing 2 3.44286
TCF4 transcription factor 4 3.44098
TSC22D2 TSC22 domain family, member 2 3.44011
NTSR2 neurotensin receptor 2 3.43904
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 3.43552
LMO2 LIM domain only 2 (rhombotin-like 1) 3.42578
AKT1 v-akt murine thymoma viral oncogene homolog 1 3.41719
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 3.41489
AKAP7 A kinase (PRKA) anchor protein 7 3.41183
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 3.4105
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 3.41031
SLITRK5 SLIT and NTRK-like family, member 5 3.40461
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 3.40317
GTPBP2 GTP binding protein 2 3.39682
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 3.39579
SOX15 SRY (sex determining region Y)-box 15 3.393
RAB3A RAB3A, member RAS oncogene family 3.38913
USP25 ubiquitin specific peptidase 25 3.38803
MATK megakaryocyte-associated tyrosine kinase 3.3873
KCMF1 potassium channel modulatory factor 1 3.38692
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 3.38626
UBE2I ubiquitin-conjugating enzyme E2I 3.38223
OLFM1 olfactomedin 1 3.38215
AFTPH aftiphilin 3.3717
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 3.36732
FAM184A family with sequence similarity 184, member A 3.36585
NTS neurotensin 3.3568
OR2B6 olfactory receptor, family 2, subfamily B, member 6 3.35349
MRAS muscle RAS oncogene homolog 3.35327
ODR4 odr-4 GPCR localization factor homolog 3.34897
DAAM2 dishevelled associated activator of morphogenesis 2 3.34729
BTG2-DT BTG2 divergent transcript 3.34435
ADAM17 ADAM metallopeptidase domain 17 3.3423
POU5F1B POU class 5 homeobox 1B 3.33943
GDE1 glycerophosphodiester phosphodiesterase 1 3.3387
ANKMY2 ankyrin repeat and MYND domain containing 2 3.33313
DPPA4 developmental pluripotency associated 4 3.33172
LIAS lipoic acid synthetase 3.32974
NR4A2 nuclear receptor subfamily 4, group A, member 2 3.32048
FGR FGR proto-oncogene, Src family tyrosine kinase 3.3168
CGA glycoprotein hormones, alpha polypeptide 3.31575
TSPAN32 tetraspanin 32 3.31336
TTYH1 tweety family member 1 3.31003
QPCT glutaminyl-peptide cyclotransferase 3.30564
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 3.30494
BLTP1 bridge-like lipid transfer protein family member 1 3.29523
CCK cholecystokinin 3.29162
TLE3 transducin-like enhancer of split 3 3.28966
SH3BP4 SH3-domain binding protein 4 3.28439
SNX3 sorting nexin 3 3.28325
LTBP1 latent transforming growth factor beta binding protein 1 3.28245
SEC63 SEC63 homolog (S. cerevisiae) 3.28104
NPTXR neuronal pentraxin receptor 3.27786
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 3.27696
C10ORF95 chromosome 10 open reading frame 95 3.27508
MDRV muscular dystrophy, with rimmed vacuoles 3.27091
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 3.27042
HOMER2 homer scaffolding protein 2 3.26869
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 3.26655
PKD2L1 polycystic kidney disease 2-like 1 3.26604
FGD1 FYVE, RhoGEF and PH domain containing 1 3.26073
CCL7 chemokine (C-C motif) ligand 7 3.25424
FHL3 four and a half LIM domains 3 3.25365
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.24949
SOAT2 sterol O-acyltransferase 2 3.24822
MCL1 myeloid cell leukemia 1 3.24712
DLX4 distal-less homeobox 4 3.24665
AKAP12 A kinase (PRKA) anchor protein 12 3.24454
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 3.2412
RUVBL1 RuvB-like AAA ATPase 1 3.23935
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 3.2299
PYGM phosphorylase, glycogen, muscle 3.22882
TTLL7 tubulin tyrosine ligase-like family member 7 3.22372
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 3.2221
SP110 SP110 nuclear body protein 3.21792
TSLIG3A tRNA splicing ligase complex subunit 3A 3.21692
DMD dystrophin 3.21339
TNPO1 transportin 1 3.20739
CLN3 ceroid-lipofuscinosis, neuronal 3 3.20139
SV2B synaptic vesicle glycoprotein 2B 3.20139
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 3.19734
MAP2 microtubule-associated protein 2 3.19726
SLCO1C1 solute carrier organic anion transporter family, member 1C1 3.19206
DPF3 D4, zinc and double PHD fingers, family 3 3.1872
LRIF1 ligand dependent nuclear receptor interacting factor 1 3.18644
MBD4 methyl-CpG binding domain protein 4 3.18332
TRIP13 thyroid hormone receptor interactor 13 3.18291
CUBN cubilin (intrinsic factor-cobalamin receptor) 3.1815
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.17987
IL36G interleukin 36, gamma 3.1797
TMSB15A thymosin beta 15a 3.17535
SS18 synovial sarcoma translocation, chromosome 18 3.17519
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 3.17358
PEX11A peroxisomal biogenesis factor 11 alpha 3.16791
EFNA4 ephrin-A4 3.16758
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.1656
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 3.16004
FSD1 fibronectin type III and SPRY domain containing 1 3.15887
SLC30A1 solute carrier family 30 (zinc transporter), member 1 3.15073
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 3.14698
MARF1 meiosis regulator and mRNA stability factor 1 3.14677
FNDC11 fibronectin type III domain containing 11 3.13915
TLE4 transducin-like enhancer of split 4 3.13753
ZNF331 zinc finger protein 331 3.13179
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 3.12784
RAB7A RAB7A, member RAS oncogene family 3.12655
EXOC7 exocyst complex component 7 3.12553
AQP5 aquaporin 5 3.12093
TRIM33 tripartite motif containing 33 3.11567
CDK5 cyclin-dependent kinase 5 3.1127
ZNF134 zinc finger protein 134 3.11155
RASL10A RAS-like, family 10, member A 3.11147
TMOD1 tropomodulin 1 3.10741
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 3.10214
CDH10 cadherin 10, type 2 (T2-cadherin) 3.09907
TMPRSS15 transmembrane protease, serine 15 3.09385
LYPD1 LY6/PLAUR domain containing 1 3.08552
ABI2 abl-interactor 2 3.08353
CTRL chymotrypsin-like 3.08234
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 3.07912
NFYC nuclear transcription factor Y, gamma 3.07881
CELA2A chymotrypsin-like elastase family, member 2A 3.07333
TEC tec protein tyrosine kinase 3.06832
FOXC2 forkhead box C2 3.06785
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 3.06267
EDA2R ectodysplasin A2 receptor 3.05619
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.05206
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 3.04914
EBF2 early B-cell factor 2 3.04869
ALG6 ALG6, alpha-1,3-glucosyltransferase 3.04835
SIRPA signal-regulatory protein alpha 3.04778
C6ORF15 chromosome 6 open reading frame 15 3.04692
SH3GLB1 SH3-domain GRB2-like endophilin B1 3.04566
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 3.0436
GULP1 GULP, engulfment adaptor PTB domain containing 1 3.04169
IDS iduronate 2-sulfatase 3.0387
ADGRB3 adhesion G protein-coupled receptor B3 3.03699
PLIN3 perilipin 3 3.02864
ZNF638 zinc finger protein 638 3.02822
NANOG Nanog homeobox 3.0225
HUS1 HUS1 checkpoint homolog (S. pombe) 3.02159
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 3.01624
EPHA5 EPH receptor A5 3.01572
NR4A1 nuclear receptor subfamily 4, group A, member 1 3.01251
SETD3 SET domain containing 3 3.01077
PDCD6 programmed cell death 6 3.00579
CNOT6 CCR4-NOT transcription complex, subunit 6 3.00203
PEX19 peroxisomal biogenesis factor 19 3.00119
DUSP14 dual specificity phosphatase 14 3.00024

decreased expression

Symbol Name Standardized Value
BCL7B B-cell CLL/lymphoma 7B -7.47881
IRX5 iroquois homeobox 5 -6.87982
IL21R interleukin 21 receptor -6.35967
RPS25 ribosomal protein S25 -6.1814
ARHGAP26 Rho GTPase activating protein 26 -6.14573
POLR1D polymerase (RNA) I polypeptide D, 16kDa -6.08824
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -5.97735
RPL4 ribosomal protein L4 -5.96511
TMPRSS4 transmembrane protease, serine 4 -5.76934
TSPAN15 tetraspanin 15 -5.63442
CALCR calcitonin receptor -5.48553
GPR85 G protein-coupled receptor 85 -5.3207
IL2RB interleukin 2 receptor, beta -5.21535
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -5.19308
OVOL2 ovo-like zinc finger 2 -5.19292
GOSR1 golgi SNAP receptor complex member 1 -5.14088
PCNA proliferating cell nuclear antigen -5.0748
HMGB1 high mobility group box 1 -5.0469
EPHB2 EPH receptor B2 -5.04429
SAP18 Sin3A-associated protein, 18kDa -4.94079
FAM13C family with sequence similarity 13, member C -4.89938
RPS20 ribosomal protein S20 -4.89719
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 -4.88869
TYMS thymidylate synthetase -4.855
TTLL5 tubulin tyrosine ligase-like family member 5 -4.80333
TNF tumor necrosis factor -4.70424
RPH3AL rabphilin 3A-like (without C2 domains) -4.68963
MINDY1 MINDY lysine 48 deubiquitinase 1 -4.67688
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -4.67409
ARSL arylsulfatase L -4.66585
LAMA3 laminin, alpha 3 -4.5992
NACA nascent polypeptide-associated complex alpha subunit -4.59703
OR7A10 olfactory receptor, family 7, subfamily A, member 10 -4.58274
SLC25A38 solute carrier family 25, member 38 -4.57496
BAIAP2L2 BAI1-associated protein 2-like 2 -4.54954
GNB5 guanine nucleotide binding protein (G protein), beta 5 -4.50701
SKAP1 src kinase associated phosphoprotein 1 -4.48294
CXCL5 chemokine (C-X-C motif) ligand 5 -4.48171
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -4.47838
RPL28 ribosomal protein L28 -4.46757
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -4.43357
CKS2 CDC28 protein kinase regulatory subunit 2 -4.42668
CCL5 chemokine (C-C motif) ligand 5 -4.37974
MMP12 matrix metallopeptidase 12 -4.37862
ITGA1 integrin, alpha 1 -4.3631
ADAM2 ADAM metallopeptidase domain 2 -4.32685
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.30066
CCR8 chemokine (C-C motif) receptor 8 -4.29592
RPL12 ribosomal protein L12 -4.28653
SLAMF1 signaling lymphocytic activation molecule family member 1 -4.25865
KDM5A lysine (K)-specific demethylase 5A -4.2577
GIMAP5 GTPase, IMAP family member 5 -4.25509
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -4.23742
GNLY granulysin -4.22453
SAC3D1 SAC3 domain containing 1 -4.22356
RHOA ras homolog family member A -4.22043
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -4.20049
RAB33A RAB33A, member RAS oncogene family -4.19754
TNIK TRAF2 and NCK interacting kinase -4.18588
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -4.18437
SAP30L-AS1 SAP30L antisense RNA 1 (head to head) -4.18377
PAPPA2 pappalysin 2 -4.17706
GLB1L2 galactosidase, beta 1-like 2 -4.17692
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -4.17396
IGSF9B immunoglobulin superfamily, member 9B -4.16387
DENND2D DENN/MADD domain containing 2D -4.15204
NME1 NME/NM23 nucleoside diphosphate kinase 1 -4.14191
ALOX15B arachidonate 15-lipoxygenase, type B -4.12523
RPS3 ribosomal protein S3 -4.11124
GP6 glycoprotein VI (platelet) -4.08957
RCAN3 RCAN family member 3 -4.07332
CRYGB crystallin, gamma B -4.06066
OR7E14P olfactory receptor, family 7, subfamily E, member 14 pseudogene -4.0519
FAM110B family with sequence similarity 110, member B -4.04948
CD3G CD3g molecule, gamma (CD3-TCR complex) -4.01257
LZTS3 leucine zipper, putative tumor suppressor family member 3 -4.00913
CCNJ cyclin J -3.99066
GARRE1 granule associated Rac and RHOG effector 1 -3.981
ZPR1 ZPR1 zinc finger -3.97332
EI24 etoposide induced 2.4 -3.95779
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -3.95649
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -3.95226
CCR3 chemokine (C-C motif) receptor 3 -3.94863
SSTR2 somatostatin receptor 2 -3.94314
PARVA parvin, alpha -3.94194
AACS acetoacetyl-CoA synthetase -3.92853
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) -3.9212
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -3.91377
ATP5MG ATP synthase membrane subunit g -3.90958
TPT1 tumor protein, translationally-controlled 1 -3.90476
PUS3 pseudouridylate synthase 3 -3.89988
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 -3.89053
CUEDC1 CUE domain containing 1 -3.88954
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -3.88439
DCPS decapping enzyme, scavenger -3.87399
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -3.87168
PFN1 profilin 1 -3.86815
CMKLR1 chemerin chemokine-like receptor 1 -3.86333
SYN3 synapsin III -3.84061
UGT8 UDP glycosyltransferase 8 -3.83578
ENO2 enolase 2 (gamma, neuronal) -3.82305
MYT1 myelin transcription factor 1 -3.82282
NKAPD1 NKAP domain containing 1 -3.81533
GMFG glia maturation factor, gamma -3.80414
PCSK7 proprotein convertase subtilisin/kexin type 7 -3.79943
ARCN1 archain 1 -3.79678
IL5 interleukin 5 -3.78753
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -3.78145
TRAF2 TNF receptor-associated factor 2 -3.77143
CTF1 cardiotrophin 1 -3.76768
CCL15 chemokine (C-C motif) ligand 15 -3.76753
CRCP CGRP receptor component -3.76638
STAT4 signal transducer and activator of transcription 4 -3.76002
ZNF22 zinc finger protein 22 -3.74013
EDA ectodysplasin A -3.738
DAXX death-domain associated protein -3.73663
TRIM15 tripartite motif containing 15 -3.73157
BCL2A1 BCL2-related protein A1 -3.73021
ATP5F1E ATP synthase F1 subunit epsilon -3.715
CYRIB CYFIP related Rac1 interactor B -3.70388
CCNT1 cyclin T1 -3.70362
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -3.69478
ICOS inducible T-cell co-stimulator -3.69008
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -3.68967
TFF3 trefoil factor 3 (intestinal) -3.68856
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -3.68502
RORA RAR-related orphan receptor A -3.68359
NGDN neuroguidin, EIF4E binding protein -3.68226
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -3.6715
C1S complement component 1, s subcomponent -3.66662
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 -3.66456
PF4V1 platelet factor 4 variant 1 -3.664
GAS2 growth arrest-specific 2 -3.66356
CAPN1 calpain 1, (mu/I) large subunit -3.65703
TBCD tubulin folding cofactor D -3.65614
C2CD2L C2CD2-like -3.65115
FOXA2 forkhead box A2 -3.64497
GLS2 glutaminase 2 (liver, mitochondrial) -3.6438
GRAP2 GRB2-related adaptor protein 2 -3.63732
RRM1 ribonucleotide reductase M1 -3.63553
GTPBP4 GTP binding protein 4 -3.61936
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 -3.61689
RPL23A ribosomal protein L23a -3.61574
EVC Ellis van Creveld protein -3.61236
IPCEF1 interaction protein for cytohesin exchange factors 1 -3.60546
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 -3.60375
H2AX H2A.X variant histone -3.60094
MINDY3 MINDY lysine 48 deubiquitinase 3 -3.59286
ST7 suppression of tumorigenicity 7 -3.59259
SMIM7 small integral membrane protein 7 -3.5917
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -3.59054
BTF3P11 basic transcription factor 3 pseudogene 11 -3.58624
TBCA tubulin folding cofactor A -3.58184
PIH1D1 PIH1 domain containing 1 -3.57773
CCDC88C coiled-coil domain containing 88C -3.57022
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -3.5608
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -3.5538
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 -3.55366
IFNW1 interferon, omega 1 -3.55136
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -3.54808
KLHL28 kelch-like family member 28 -3.54767
PPP1R13B protein phosphatase 1, regulatory subunit 13B -3.54398
PMS2P4 postmeiotic segregation increased 2 pseudogene 4 -3.53876
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -3.53664
THYN1 thymocyte nuclear protein 1 -3.53481
C2 complement component 2 -3.53073
RPL11 ribosomal protein L11 -3.52888
ZNF202 zinc finger protein 202 -3.52832
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -3.52741
PLPPR1 phospholipid phosphatase related 1 -3.52005
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -3.51942
TCP10L t-complex 10-like -3.51889
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -3.51286
LGSN lengsin, lens protein with glutamine synthetase domain -3.5114
SNX19 sorting nexin 19 -3.50972
GALK2 galactokinase 2 -3.4993
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -3.49552
PCSK6 proprotein convertase subtilisin/kexin type 6 -3.49359
NCK1 NCK adaptor protein 1 -3.47291
CCNF cyclin F -3.4594
CETN1 centrin, EF-hand protein, 1 -3.44815
TOP3A topoisomerase (DNA) III alpha -3.44119
LCK LCK proto-oncogene, Src family tyrosine kinase -3.43824
GYPC glycophorin C (Gerbich blood group) -3.43129
LTA lymphotoxin alpha -3.43051
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -3.42851
EGFL6 EGF-like-domain, multiple 6 -3.42727
RPL19 ribosomal protein L19 -3.42134
ZNF254 zinc finger protein 254 -3.4187
IFITM3 interferon induced transmembrane protein 3 -3.41666
GALR1 galanin receptor 1 -3.41271
EIF3H eukaryotic translation initiation factor 3, subunit H -3.41244
PPA1 pyrophosphatase (inorganic) 1 -3.40951
RAB11A RAB11A, member RAS oncogene family -3.40692
FAM149A family with sequence similarity 149, member A -3.39896
TACR1 tachykinin receptor 1 -3.38741
LSM12 LSM12 homolog (S. cerevisiae) -3.38612
MIS18BP1 MIS18 binding protein 1 -3.38297
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -3.38016
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) -3.37981
PROX1 prospero homeobox 1 -3.37808
AGR2 anterior gradient 2 -3.37266
S100A6 S100 calcium binding protein A6 -3.37135
COX6C cytochrome c oxidase subunit VIc -3.37026
TEX12 testis expressed 12 -3.36982
SHLD2 shieldin complex subunit 2 -3.36295
ATP5ME ATP synthase membrane subunit e -3.35912
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 -3.35894
CHIA chitinase, acidic -3.3587
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 -3.35847
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -3.35485
PARP2 poly (ADP-ribose) polymerase 2 -3.35326
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -3.3426
CYTH3 cytohesin 3 -3.34184
POGLUT1 protein O-glucosyltransferase 1 -3.34131
LAD1 ladinin 1 -3.33346
RPL14 ribosomal protein L14 -3.32629
BCL2 B-cell CLL/lymphoma 2 -3.32532
TSPAN4 tetraspanin 4 -3.32478
ATP5IF1 ATP synthase inhibitory factor subunit 1 -3.31931
A4GNT alpha-1,4-N-acetylglucosaminyltransferase -3.31679
CCL4 chemokine (C-C motif) ligand 4 -3.31266
TSPAN2 tetraspanin 2 -3.31114
ANGPTL2 angiopoietin-like 2 -3.30916
HELZ helicase with zinc finger -3.30707
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -3.30423
KITLG KIT ligand -3.30251
RPL6 ribosomal protein L6 -3.30237
EBI3 Epstein-Barr virus induced 3 -3.30137
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -3.29872
C2ORF27A chromosome 2 open reading frame 27A -3.29705
CLSPN claspin -3.29021
AHCTF1 AT hook containing transcription factor 1 -3.28647
EGOT eosinophil granule ontogeny transcript (non-protein coding) -3.28191
CSF1 colony stimulating factor 1 (macrophage) -3.27942
NT5C3A 5'-nucleotidase, cytosolic IIIA -3.2788
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -3.27845
CALML4 calmodulin-like 4 -3.27838
RS1 retinoschisin 1 -3.27503
CD2 CD2 molecule -3.27436
MINAR1 membrane integral NOTCH2 associated receptor 1 -3.27421
CD247 CD247 molecule -3.27373
COQ8A coenzyme Q8A -3.26565
CXCR6 chemokine (C-X-C motif) receptor 6 -3.26241
VIL1 villin 1 -3.25954
KMT2A lysine (K)-specific methyltransferase 2A -3.2576
LINC01587 long intergenic non-protein coding RNA 1587 -3.25354
PLD1 phospholipase D1, phosphatidylcholine-specific -3.25157
CXCR2 chemokine (C-X-C motif) receptor 2 -3.25031
LONP2 lon peptidase 2, peroxisomal -3.2485
C4ORF19 chromosome 4 open reading frame 19 -3.24578
SAR1A secretion associated, Ras related GTPase 1A -3.24093
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -3.23687
SEC14L1P1 SEC14-like 1 pseudogene 1 -3.23679
DLG5 discs, large homolog 5 (Drosophila) -3.23434
ANKRD10 ankyrin repeat domain 10 -3.22809
MRPL57 mitochondrial ribosomal protein L57 -3.22769
ASXL1 additional sex combs like transcriptional regulator 1 -3.22724
CHD7 chromodomain helicase DNA binding protein 7 -3.22722
PRSS50 protease, serine, 50 -3.22666
ATP5PF ATP synthase peripheral stalk subunit F6 -3.22502
PBOV1 prostate and breast cancer overexpressed 1 -3.22167
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) -3.21444
CST7 cystatin F (leukocystatin) -3.2114
CLDN4 claudin 4 -3.21094
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -3.20522
ABI3BP ABI family, member 3 (NESH) binding protein -3.20522
IL32 interleukin 32 -3.20438
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -3.20253
ZW10 zw10 kinetochore protein -3.19508
KSR1 kinase suppressor of ras 1 -3.18787
MYO3A myosin IIIA -3.18603
CD8A CD8a molecule -3.1832
CHEK1 checkpoint kinase 1 -3.18252
OPLAH 5-oxoprolinase (ATP-hydrolysing) -3.18177
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -3.17756
CDK12 cyclin-dependent kinase 12 -3.17651
PTMA prothymosin, alpha -3.1659
PRDX2 peroxiredoxin 2 -3.16499
FOXI1 forkhead box I1 -3.16485
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -3.16426
GPATCH1 G patch domain containing 1 -3.16258
GIPC2 GIPC PDZ domain containing family, member 2 -3.16161
CD4 CD4 molecule -3.15696
GNAS GNAS complex locus -3.15155
THAP1 THAP domain containing, apoptosis associated protein 1 -3.15042
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -3.14316
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -3.13992
ATOH1 atonal homolog 1 (Drosophila) -3.13687
RBM7 RNA binding motif protein 7 -3.13406
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -3.13271
CDC20 cell division cycle 20 -3.13252
TUBB1 tubulin, beta 1 class VI -3.13063
LRRN3 leucine rich repeat neuronal 3 -3.12241
ULBP1 UL16 binding protein 1 -3.12121
TAS2R1 taste receptor, type 2, member 1 -3.11951
SRCAP Snf2-related CREBBP activator protein -3.11749
TRPA1 transient receptor potential cation channel, subfamily A, member 1 -3.11628
ACAT1 acetyl-CoA acetyltransferase 1 -3.11383
NMT2 N-myristoyltransferase 2 -3.11169
CCL20 chemokine (C-C motif) ligand 20 -3.10085
NKG7 natural killer cell granule protein 7 -3.09845
SLC43A3 solute carrier family 43, member 3 -3.09799
RNF32 ring finger protein 32 -3.09662
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -3.09624
NUMA1 nuclear mitotic apparatus protein 1 -3.09474
MOG myelin oligodendrocyte glycoprotein -3.09383
GPX7 glutathione peroxidase 7 -3.0902
BTG1 B-cell translocation gene 1, anti-proliferative -3.08723
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -3.08447
H1-6 H1.6 linker histone, cluster member -3.07725
SMCP sperm mitochondria-associated cysteine-rich protein -3.07274
HINFP histone H4 transcription factor -3.07058
RPL22 ribosomal protein L22 -3.06942
BCL2L14 BCL2-like 14 (apoptosis facilitator) -3.06936
KCTD9 potassium channel tetramerization domain containing 9 -3.06795
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) -3.0658
ADIPOR2 adiponectin receptor 2 -3.06373
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 -3.05938
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 -3.05332
ACAA1 acetyl-CoA acyltransferase 1 -3.04932
EPHX3 epoxide hydrolase 3 -3.04687
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -3.04549
RPL10A ribosomal protein L10a -3.04536
LOC202181 SUMO-interacting motifs containing 1 pseudogene -3.04076
SLC44A1 solute carrier family 44 (choline transporter), member 1 -3.04056
IFT46 intraflagellar transport 46 -3.04014
PPIB peptidylprolyl isomerase B (cyclophilin B) -3.03913
BRD2 bromodomain containing 2 -3.03777
KLRD1 killer cell lectin-like receptor subfamily D, member 1 -3.03565
PROZ protein Z, vitamin K-dependent plasma glycoprotein -3.03292
ASIC4 acid sensing (proton gated) ion channel family member 4 -3.0271
HOOK2 hook microtubule-tethering protein 2 -3.02574
PPA2 pyrophosphatase (inorganic) 2 -3.02554
SIRPB1 signal-regulatory protein beta 1 -3.02338
KRT33A keratin 33A, type I -3.02132
SORBS2 sorbin and SH3 domain containing 2 -3.01605
HLA-DMA major histocompatibility complex, class II, DM alpha -3.01464
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -3.00293