| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dihydrostreptomycin-5751 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACAN | aggrecan |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| AFF4 | AF4/FMR2 family, member 4 |
| AGRP | agouti related neuropeptide |
| AHNAK | AHNAK nucleoprotein |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARL3 | ADP-ribosylation factor-like 3 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CCPG1 | cell cycle progression 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLEC4E | C-type lectin domain family 4, member E |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| CYTH3 | cytohesin 3 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| ECE1 | endothelin converting enzyme 1 |
| EDA | ectodysplasin A |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM49B | family with sequence similarity 49, member B |
| FBXO22 | F-box protein 22 |
| FKBP15 | FK506 binding protein 15, 133kDa |
| FRMD1 | FERM domain containing 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GK2 | glycerol kinase 2 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GRAP | GRB2-related adaptor protein |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
| GSTA3 | glutathione S-transferase alpha 3 |
| HNF1B | HNF1 homeobox B |
| HOXB3 | homeobox B3 |
| HOXD11 | homeobox D11 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF12 | Kruppel-like factor 12 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MEFV | Mediterranean fever |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MLN | motilin |
| MTMR8 | myotubularin related protein 8 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NCOR2 | nuclear receptor corepressor 2 |
| NDNF | neuron-derived neurotrophic factor |
| NF1 | neurofibromin 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NRF1 | nuclear respiratory factor 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PIP | prolactin-induced protein |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PML | promyelocytic leukemia |
| POMT2 | protein-O-mannosyltransferase 2 |
| PON1 | paraoxonase 1 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RPL3L | ribosomal protein L3-like |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOCS3 | suppressor of cytokine signaling 3 |
| SPTB | spectrin, beta, erythrocytic |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAT4 | signal transducer and activator of transcription 4 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TFEB | transcription factor EB |
| TLR1 | toll-like receptor 1 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM206 | transmembrane protein 206 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF343 | zinc finger protein 343 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCNJ | cyclin J |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CENPO | centromere protein O |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CORT | cortistatin |
| CRLF1 | cytokine receptor-like factor 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DIXDC1 | DIX domain containing 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EPHA4 | EPH receptor A4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GBX2 | gastrulation brain homeobox 2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPATCH2L | G patch domain containing 2-like |
| GRAMD1C | GRAM domain containing 1C |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BM | histone cluster 1, H2bm |
| HMG20A | high mobility group 20A |
| IL6 | interleukin 6 |
| IPO8 | importin 8 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA0754 | KIAA0754 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL12 | kelch-like family member 12 |
| KRT9 | keratin 9, type I |
| LHX6 | LIM homeobox 6 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGEB2 | melanoma antigen family B2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MT1M | metallothionein 1M |
| MTA2 | metastasis associated 1 family, member 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OCLN | occludin |
| P3H2 | prolyl 3-hydroxylase 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF146 | ring finger protein 146 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RRAGB | Ras-related GTP binding B |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| TBC1D12 | TBC1 domain family, member 12 |
| TBC1D19 | TBC1 domain family, member 19 |
| TMC7 | transmembrane channel-like 7 |
| TMEM209 | transmembrane protein 209 |
| TNS2 | tensin 2 |
| TOM1 | target of myb1 (chicken) |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBB2B | tubulin, beta 2B class IIb |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UGT8 | UDP glycosyltransferase 8 |
| UNKL | unkempt family zinc finger-like |
| USP20 | ubiquitin specific peptidase 20 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZNF230 | zinc finger protein 230 |
| ZNF253 | zinc finger protein 253 |
| ZNF480 | zinc finger protein 480 |
| ZNF671 | zinc finger protein 671 |
