| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dihydrostreptomycin-6228 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADCY1 | adenylate cyclase 1 (brain) |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANGPTL2 | angiopoietin-like 2 |
| APOC1 | apolipoprotein C-I |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AURKA | aurora kinase A |
| BCL6 | B-cell CLL/lymphoma 6 |
| BIN1 | bridging integrator 1 |
| BTG2 | BTG family, member 2 |
| CEP104 | centrosomal protein 104kDa |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLDN1 | claudin 1 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL1A1 | collagen, type I, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CUL4B | cullin 4B |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| EXOC7 | exocyst complex component 7 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM110B | family with sequence similarity 110, member B |
| FLT4 | fms-related tyrosine kinase 4 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GID4 | GID complex subunit 4 |
| GLG1 | golgi glycoprotein 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GPATCH2L | G patch domain containing 2-like |
| GPR176 | G protein-coupled receptor 176 |
| GTPBP4 | GTP binding protein 4 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFT38 | intraflagellar transport 38 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL2 | interleukin 2 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IRF6 | interferon regulatory factor 6 |
| IZUMO4 | IZUMO family member 4 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MATN1 | matrilin 1, cartilage matrix protein |
| MED16 | mediator complex subunit 16 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MSR1 | macrophage scavenger receptor 1 |
| NKX3-1 | NK3 homeobox 1 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPHP4 | nephronophthisis 4 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLCH1 | phospholipase C, eta 1 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRF1 | perforin 1 (pore forming protein) |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RNF24 | ring finger protein 24 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D22A | TBC1 domain family, member 22A |
| TCTA | T-cell leukemia translocation altered |
| TFF2 | trefoil factor 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM161A | transmembrane protein 161A |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR91 | WD repeat domain 91 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF701 | zinc finger protein 701 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANKRD28 | ankyrin repeat domain 28 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATP13A2 | ATPase type 13A2 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| CAPG | capping protein (actin filament), gelsolin-like |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCNJ | cyclin J |
| CDK9 | cyclin-dependent kinase 9 |
| CLK1 | CDC-like kinase 1 |
| COQ6 | coenzyme Q6 monooxygenase |
| CORO2A | coronin, actin binding protein, 2A |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DENND4C | DENN/MADD domain containing 4C |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFHD2 | EF-hand domain family, member D2 |
| FAM155B | family with sequence similarity 155, member B |
| FAM63A | family with sequence similarity 63, member A |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HELZ | helicase with zinc finger |
| HMGB3 | high mobility group box 3 |
| ICK | intestinal cell (MAK-like) kinase |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| JADE1 | jade family PHD finger 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIF3B | kinesin family member 3B |
| KPTN | kaptin (actin binding protein) |
| LRRC49 | leucine rich repeat containing 49 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| METTL2B | methyltransferase like 2B |
| MICALL2 | MICAL-like 2 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MUTYH | mutY homolog |
| MYO9A | myosin IXA |
| NABP2 | nucleic acid binding protein 2 |
| NES | nestin |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PC | pyruvate carboxylase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDGFRL | platelet-derived growth factor receptor-like |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLH | polymerase (DNA directed), eta |
| POMZP3 | POM121 and ZP3 fusion |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR3 | proline rich 3 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB23 | RAB23, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM42 | RNA binding motif protein 42 |
| RBM4B | RNA binding motif protein 4B |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF113A | ring finger protein 113A |
| RNF146 | ring finger protein 146 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| STRN4 | striatin, calmodulin binding protein 4 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| THUMPD2 | THUMP domain containing 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM66 | tripartite motif containing 66 |
| TSPAN15 | tetraspanin 15 |
| UBXN6 | UBX domain protein 6 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZFHX3 | zinc finger homeobox 3 |
