dilated cardiomyopathy Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An intrinsic cardiomyopathy that results in damage to the myocardium causing the heart to pump blood inefficiently.|A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.|decreased function of the heart associated with cardiac enlargement and congestive heart failure (Experimental Factor Ontology, EFO_0000407)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:12930
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Genes

12 genes associated with the disease dilated cardiomyopathy in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 1.70767
BAG3 BCL2-associated athanogene 3 1.6622
ZBTB17 zinc finger and BTB domain containing 17 1.50906
HCG22 HLA complex group 22 1.35253
AKAP13 A kinase (PRKA) anchor protein 13 1.30031
RUNX1 runt-related transcription factor 1 1.29761
ADD2 adducin 2 (beta) 1.28797
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 1.23283
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.16574
VWC2L von Willebrand factor C domain containing protein 2-like 0.837296
LOC100507462 uncharacterized LOC100507462 0.427749
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.423102