dilated dorsal aorta Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description stretched or widened aperture of the luminal space of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation (Mammalian Phenotype Ontology, MP_0004068)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004068
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17 gene mutations causing the dilated dorsal aorta phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
CCM2 cerebral cavernous malformation 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CXADR coxsackie virus and adenovirus receptor
CYR61 cysteine-rich, angiogenic inducer, 61
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
KAT7 K(lysine) acetyltransferase 7
MEF2C myocyte enhancer factor 2C
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NGFR nerve growth factor receptor
PNPLA6 patatin-like phospholipase domain containing 6
RASIP1 Ras interacting protein 1
SCX scleraxis basic helix-loop-helix transcription factor
SMAD5 SMAD family member 5
TAL1 T-cell acute lymphocytic leukemia 1
TLL1 tolloid-like 1
ZMIZ1 zinc finger, MIZ-type containing 1