dilazep-2294 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dilazep-2294 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
BDKRB1 bradykinin receptor B1
BGN biglycan
C14ORF79 chromosome 14 open reading frame 79
C19ORF66 chromosome 19 open reading frame 66
C8ORF60 chromosome 8 open reading frame 60
CALB2 calbindin 2
CD48 CD48 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP164 centrosomal protein 164kDa
COL7A1 collagen, type VII, alpha 1
CTSZ cathepsin Z
CYB5A cytochrome b5 type A (microsomal)
DGAT1 diacylglycerol O-acyltransferase 1
DGCR2 DiGeorge syndrome critical region gene 2
DNASE1 deoxyribonuclease I
EGR1 early growth response 1
ELL elongation factor RNA polymerase II
FAM212B family with sequence similarity 212, member B
FAP fibroblast activation protein, alpha
FGF4 fibroblast growth factor 4
FRMD1 FERM domain containing 1
FRMD4B FERM domain containing 4B
FSCN1 fascin actin-bundling protein 1
FST follistatin
GAS7 growth arrest-specific 7
GLS glutaminase
GPR153 G protein-coupled receptor 153
GPR50 G protein-coupled receptor 50
IDUA iduronidase, alpha-L-
INO80D INO80 complex subunit D
JMJD6 jumonji domain containing 6
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCTD17 potassium channel tetramerization domain containing 17
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1549L KIAA1549-like
KLHL22 kelch-like family member 22
KRT15 keratin 15, type I
KRT83 keratin 83, type II
LHX2 LIM homeobox 2
LINC00597 long intergenic non-protein coding RNA 597
LMAN1 lectin, mannose-binding, 1
LZTS1 leucine zipper, putative tumor suppressor 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MDFI MyoD family inhibitor
MID1 midline 1
MIER2 mesoderm induction early response 1, family member 2
MKL1 megakaryoblastic leukemia (translocation) 1
MLXIP MLX interacting protein
MTL5 metallothionein-like 5, testis-specific (tesmin)
NDN necdin, melanoma antigen (MAGE) family member
OR1E1 olfactory receptor, family 1, subfamily E, member 1
PCDH1 protocadherin 1
PCNX pecanex homolog (Drosophila)
PLXDC1 plexin domain containing 1
PLXNB3 plexin B3
PML promyelocytic leukemia
PPARD peroxisome proliferator-activated receptor delta
PRDX2 peroxiredoxin 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBBP9 retinoblastoma binding protein 9
RHBDD3 rhomboid domain containing 3
RPS3A ribosomal protein S3A
SAMD9 sterile alpha motif domain containing 9
SDC2 syndecan 2
SIRT4 sirtuin 4
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC38A7 solute carrier family 38, member 7
SPDEF SAM pointed domain containing ETS transcription factor
SPN sialophorin
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTB spectrin, beta, erythrocytic
STYK1 serine/threonine/tyrosine kinase 1
TCF3 transcription factor 3
TFDP3 transcription factor Dp family, member 3
TKTL1 transketolase-like 1
TLN1 talin 1
TM4SF5 transmembrane 4 L six family member 5
TMEM212 transmembrane protein 212
TNS1 tensin 1
TPK1 thiamin pyrophosphokinase 1
TPM3 tropomyosin 3
TSC22D4 TSC22 domain family, member 4
TYMP thymidine phosphorylase
UNC13A unc-13 homolog A (C. elegans)
UNC5B unc-5 homolog B (C. elegans)
UPK3A uroplakin 3A
UPK3B uroplakin 3B
VCX2 variable charge, X-linked 2
VIPR2 vasoactive intestinal peptide receptor 2
XYLT1 xylosyltransferase I
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSF2 acyl-CoA synthetase family member 2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB2 arrestin, beta 2
ASB9 ankyrin repeat and SOCS box containing 9
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTBD7 BTB (POZ) domain containing 7
BTF3P12 basic transcription factor 3 pseudogene 12
C2CD2 C2 calcium-dependent domain containing 2
C5AR2 complement component 5a receptor 2
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD83 CD83 molecule
CENPJ centromere protein J
CHML choroideremia-like (Rab escort protein 2)
CINP cyclin-dependent kinase 2 interacting protein
CLSPN claspin
CPTP ceramide-1-phosphate transfer protein
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTX4 deltex 4, E3 ubiquitin ligase
EML4 echinoderm microtubule associated protein like 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FBXO2 F-box protein 2
FKBP5 FK506 binding protein 5
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L2 galactosidase, beta 1-like 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX2 glutathione peroxidase 2
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
IFT140 intraflagellar transport 140
IRAK4 interleukin-1 receptor-associated kinase 4
ITPKB inositol-trisphosphate 3-kinase B
KIAA0895 KIAA0895
KLF11 Kruppel-like factor 11
KLF3 Kruppel-like factor 3 (basic)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MAGEF1 melanoma antigen family F1
MAST3 microtubule associated serine/threonine kinase 3
NABP2 nucleic acid binding protein 2
NFE2L3 nuclear factor, erythroid 2-like 3
NLRX1 NLR family member X1
OLFML3 olfactomedin-like 3
PCDHB13 protocadherin beta 13
PER3 period circadian clock 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMEL premelanosome protein
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RABL6 RAB, member RAS oncogene family-like 6
RFTN1 raftlin, lipid raft linker 1
RNF122 ring finger protein 122
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RWDD3 RWD domain containing 3
SLC12A8 solute carrier family 12, member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLMO1 slowmo homolog 1 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SPON2 spondin 2, extracellular matrix protein
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D17 TBC1 domain family, member 17
TESC tescalcin
TEX40 testis expressed 40
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TRIM25 tripartite motif containing 25
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPYL2 TSPY-like 2
VAX2 ventral anterior homeobox 2
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB48 zinc finger and BTB domain containing 48
ZBTB6 zinc finger and BTB domain containing 6
ZNF226 zinc finger protein 226
ZNF271P zinc finger protein 271, pseudogene
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN26 zinc finger and SCAN domain containing 26