dilazep-2333 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dilazep-2333 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ATAT1 alpha tubulin acetyltransferase 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AXIN1 axin 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BTBD7 BTB (POZ) domain containing 7
C1ORF115 chromosome 1 open reading frame 115
C5 complement component 5
CD70 CD70 molecule
CD82 CD82 molecule
CDK13 cyclin-dependent kinase 13
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNR2 cannabinoid receptor 2 (macrophage)
CTC1 CTS telomere maintenance complex component 1
CTNND2 catenin (cadherin-associated protein), delta 2
CTSO cathepsin O
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DOK5 docking protein 5
E2F4 E2F transcription factor 4, p107/p130-binding
EFR3B EFR3 homolog B (S. cerevisiae)
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ERBB2 erb-b2 receptor tyrosine kinase 2
EXTL3 exostosin-like glycosyltransferase 3
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM63A family with sequence similarity 63, member A
FGF23 fibroblast growth factor 23
FGGY FGGY carbohydrate kinase domain containing
FHL1 four and a half LIM domains 1
FOXO1 forkhead box O1
GBP2 guanylate binding protein 2, interferon-inducible
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRIP2 glutamate receptor interacting protein 2
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HFE hemochromatosis
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H2BG histone cluster 1, H2bg
HIST1H2BJ histone cluster 1, H2bj
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ICOSLG inducible T-cell co-stimulator ligand
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
IQCC IQ motif containing C
IQSEC1 IQ motif and Sec7 domain 1
KYNU kynureninase
LARP7 La ribonucleoprotein domain family, member 7
LIMD2 LIM domain containing 2
LRP1 low density lipoprotein receptor-related protein 1
MAL mal, T-cell differentiation protein
MAP4 microtubule-associated protein 4
MARK4 MAP/microtubule affinity-regulating kinase 4
MAX MYC associated factor X
MMP9 matrix metallopeptidase 9
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
PAPPA2 pappalysin 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCGF2 polycomb group ring finger 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLK4 polo-like kinase 4
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTCH1 patched 1
PTCRA pre T-cell antigen receptor alpha
RAB35 RAB35, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCAN1 regulator of calcineurin 1
RGS3 regulator of G-protein signaling 3
RPL10L ribosomal protein L10-like
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SCLY selenocysteine lyase
SEC14L1 SEC14-like 1 (S. cerevisiae)
SIGLEC7 sialic acid binding Ig-like lectin 7
SIGLEC8 sialic acid binding Ig-like lectin 8
STS steroid sulfatase (microsomal), isozyme S
SYNJ2 synaptojanin 2
TBC1D2 TBC1 domain family, member 2
TBCD tubulin folding cofactor D
TCF3 transcription factor 3
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THRAP3 thyroid hormone receptor associated protein 3
TMC5 transmembrane channel-like 5
TMCO3 transmembrane and coiled-coil domains 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRAPPC9 trafficking protein particle complex 9
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSC22D3 TSC22 domain family, member 3
UHRF1BP1L UHRF1 binding protein 1-like
VCAM1 vascular cell adhesion molecule 1
VEGFC vascular endothelial growth factor C
ZNF428 zinc finger protein 428
ZNF675 zinc finger protein 675
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ALG12 ALG12, alpha-1,6-mannosyltransferase
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOBR apolipoprotein B receptor
ARRB2 arrestin, beta 2
ARSB arylsulfatase B
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BACE1 beta-site APP-cleaving enzyme 1
BAG4 BCL2-associated athanogene 4
BIK BCL2-interacting killer (apoptosis-inducing)
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF21 chromosome 11 open reading frame 21
C2CD2 C2 calcium-dependent domain containing 2
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN1 calpain 1, (mu/I) large subunit
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CLCN6 chloride channel, voltage-sensitive 6
CLDN15 claudin 15
CLEC7A C-type lectin domain family 7, member A
CSF1R colony stimulating factor 1 receptor
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXCR2 chemokine (C-X-C motif) receptor 2
DBF4B DBF4 zinc finger B
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DSPP dentin sialophosphoprotein
DUSP2 dual specificity phosphatase 2
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EFHC1 EF-hand domain (C-terminal) containing 1
EGLN2 egl-9 family hypoxia-inducible factor 2
ELP6 elongator acetyltransferase complex subunit 6
FHL3 four and a half LIM domains 3
FLJ21369 uncharacterized protein FLJ21369
GALE UDP-galactose-4-epimerase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRAMD1B GRAM domain containing 1B
GSTCD glutathione S-transferase, C-terminal domain containing
HINFP histone H4 transcription factor
HMGA2 high mobility group AT-hook 2
HSPA4L heat shock 70kDa protein 4-like
HYAL2 hyaluronoglucosaminidase 2
JMJD4 jumonji domain containing 4
KAT2B K(lysine) acetyltransferase 2B
LAX1 lymphocyte transmembrane adaptor 1
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC42 leucine rich repeat containing 42
MAP6D1 MAP6 domain containing 1
MAPK3 mitogen-activated protein kinase 3
MATK megakaryocyte-associated tyrosine kinase
MOCS3 molybdenum cofactor synthesis 3
MON1B MON1 secretory trafficking family member B
MPI mannose phosphate isomerase
NCS1 neuronal calcium sensor 1
NIPAL2 NIPA-like domain containing 2
NLK nemo-like kinase
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NTSR1 neurotensin receptor 1 (high affinity)
PDZD7 PDZ domain containing 7
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLM polymerase (DNA directed), mu
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBM42 RNA binding motif protein 42
RBM47 RNA binding motif protein 47
RETN resistin
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RNASE3 ribonuclease, RNase A family, 3
RWDD3 RWD domain containing 3
SETD1A SET domain containing 1A
SGMS1 sphingomyelin synthase 1
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC35E3 solute carrier family 35, member E3
SLFN12 schlafen family member 12
SPATS2 spermatogenesis associated, serine-rich 2
SPP1 secreted phosphoprotein 1
SREBF1 sterol regulatory element binding transcription factor 1
STAG3 stromal antigen 3
TASP1 taspase, threonine aspartase, 1
TCTN2 tectonic family member 2
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TMC7 transmembrane channel-like 7
TRIM5 tripartite motif containing 5
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSPAN13 tetraspanin 13
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC93B1 unc-93 homolog B1 (C. elegans)
USP19 ubiquitin specific peptidase 19
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WBP2 WW domain binding protein 2
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF37BP zinc finger protein 37B, pseudogene
ZNF701 zinc finger protein 701
ZNF8 zinc finger protein 8