| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the dilazep-3665 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AFF2 | AF4/FMR2 family, member 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX12 | arachidonate 12-lipoxygenase |
| AMH | anti-Mullerian hormone |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARMC4 | armadillo repeat containing 4 |
| ATP10B | ATPase, class V, type 10B |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BMP7 | bone morphogenetic protein 7 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C8A | complement component 8, alpha polypeptide |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CCDC132 | coiled-coil domain containing 132 |
| CCL16 | chemokine (C-C motif) ligand 16 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLIC5 | chloride intracellular channel 5 |
| COL9A3 | collagen, type IX, alpha 3 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| ECE1 | endothelin converting enzyme 1 |
| EPS8L1 | EPS8-like 1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FXYD1 | FXYD domain containing ion transport regulator 1 |
| GAP43 | growth associated protein 43 |
| GAS7 | growth arrest-specific 7 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HIST3H3 | histone cluster 3, H3 |
| IFNA1 | interferon, alpha 1 |
| IL1A | interleukin 1, alpha |
| INADL | InaD-like (Drosophila) |
| IQGAP2 | IQ motif containing GTPase activating protein 2 |
| ITM2A | integral membrane protein 2A |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KIAA0319L | KIAA0319-like |
| LDHC | lactate dehydrogenase C |
| LRRC15 | leucine rich repeat containing 15 |
| LRRC17 | leucine rich repeat containing 17 |
| LYRM9 | LYR motif containing 9 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MC5R | melanocortin 5 receptor |
| MFAP3L | microfibrillar-associated protein 3-like |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MUC3B | mucin 3B, cell surface associated |
| MYO7B | myosin VIIB |
| NCAM1 | neural cell adhesion molecule 1 |
| OMG | oligodendrocyte myelin glycoprotein |
| PDLIM3 | PDZ and LIM domain 3 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIP | prolactin-induced protein |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PROX1 | prospero homeobox 1 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| QPCT | glutaminyl-peptide cyclotransferase |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| REC8 | REC8 meiotic recombination protein |
| RGSL1 | regulator of G-protein signaling like 1 |
| RPL18 | ribosomal protein L18 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RSU1 | Ras suppressor protein 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCN3B | sodium channel, voltage gated, type III beta subunit |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLITRK3 | SLIT and NTRK-like family, member 3 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPEF1 | sperm flagellar 1 |
| SPRR2B | small proline-rich protein 2B |
| SYNJ2 | synaptojanin 2 |
| SYT11 | synaptotagmin XI |
| TAPBP | TAP binding protein (tapasin) |
| THY1 | Thy-1 cell surface antigen |
| TK2 | thymidine kinase 2, mitochondrial |
| TLR5 | toll-like receptor 5 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TPP1 | tripeptidyl peptidase I |
| TRIM29 | tripartite motif containing 29 |
| TRIM3 | tripartite motif containing 3 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TXK | TXK tyrosine kinase |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZNF407 | zinc finger protein 407 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CA9 | carbonic anhydrase IX |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CAPN15 | calpain 15 |
| CBX8 | chromobox homolog 8 |
| CCDC106 | coiled-coil domain containing 106 |
| CHMP6 | charged multivesicular body protein 6 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CORO1A | coronin, actin binding protein, 1A |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIO3 | deiodinase, iodothyronine, type III |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EFNA3 | ephrin-A3 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EPHA4 | EPH receptor A4 |
| FAM188A | family with sequence similarity 188, member A |
| FAM50B | family with sequence similarity 50, member B |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALK1 | galactokinase 1 |
| GBX2 | gastrulation brain homeobox 2 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPR1 | G protein-coupled receptor 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HAS2 | hyaluronan synthase 2 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| IL17RB | interleukin 17 receptor B |
| IL33 | interleukin 33 |
| IL6 | interleukin 6 |
| IL7R | interleukin 7 receptor |
| KRT15 | keratin 15, type I |
| LHX6 | LIM homeobox 6 |
| LRRC61 | leucine rich repeat containing 61 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAL | mal, T-cell differentiation protein |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MLYCD | malonyl-CoA decarboxylase |
| MMP3 | matrix metallopeptidase 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MT1M | metallothionein 1M |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| POLM | polymerase (DNA directed), mu |
| PRPH | peripherin |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTHLH | parathyroid hormone-like hormone |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RNF146 | ring finger protein 146 |
| RNF31 | ring finger protein 31 |
| RPA4 | replication protein A4, 30kDa |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SCARA3 | scavenger receptor class A, member 3 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMO | smoothened, frizzled class receptor |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TLR2 | toll-like receptor 2 |
| TMEM121 | transmembrane protein 121 |
| TMEM209 | transmembrane protein 209 |
| TMEM40 | transmembrane protein 40 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDR4 | WD repeat domain 4 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZNF215 | zinc finger protein 215 |
| ZNF350 | zinc finger protein 350 |
| ZNF510 | zinc finger protein 510 |
| ZNF675 | zinc finger protein 675 |
| ZNF76 | zinc finger protein 76 |
| ZNF768 | zinc finger protein 768 |