dilazep-3665 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the dilazep-3665 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AFF2 AF4/FMR2 family, member 2
ALDOB aldolase B, fructose-bisphosphate
ALOX12 arachidonate 12-lipoxygenase
AMH anti-Mullerian hormone
AQP3 aquaporin 3 (Gill blood group)
ARMC4 armadillo repeat containing 4
ATP10B ATPase, class V, type 10B
BAAT bile acid CoA:amino acid N-acyltransferase
BMP7 bone morphogenetic protein 7
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C8A complement component 8, alpha polypeptide
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CCDC132 coiled-coil domain containing 132
CCL16 chemokine (C-C motif) ligand 16
CCL27 chemokine (C-C motif) ligand 27
CFAP45 cilia and flagella associated protein 45
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLIC5 chloride intracellular channel 5
COL9A3 collagen, type IX, alpha 3
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSNK1G1 casein kinase 1, gamma 1
CYBA cytochrome b-245, alpha polypeptide
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
ECE1 endothelin converting enzyme 1
EPS8L1 EPS8-like 1
FSCN3 fascin actin-bundling protein 3, testicular
FXYD1 FXYD domain containing ion transport regulator 1
GAP43 growth associated protein 43
GAS7 growth arrest-specific 7
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GSTTP1 glutathione S-transferase theta pseudogene 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST3H3 histone cluster 3, H3
IFNA1 interferon, alpha 1
IL1A interleukin 1, alpha
INADL InaD-like (Drosophila)
IQGAP2 IQ motif containing GTPase activating protein 2
ITM2A integral membrane protein 2A
KANK1 KN motif and ankyrin repeat domains 1
KIAA0319L KIAA0319-like
LDHC lactate dehydrogenase C
LRRC15 leucine rich repeat containing 15
LRRC17 leucine rich repeat containing 17
LYRM9 LYR motif containing 9
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC5R melanocortin 5 receptor
MFAP3L microfibrillar-associated protein 3-like
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MNMIP1 manchette microtubule inner protein 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
MUC3B mucin 3B, cell surface associated
MYO7B myosin VIIB
NCAM1 neural cell adhesion molecule 1
OMG oligodendrocyte myelin glycoprotein
PDLIM3 PDZ and LIM domain 3
PGAP3 post-GPI attachment to proteins 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIP prolactin-induced protein
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PROX1 prospero homeobox 1
PTGDR2 prostaglandin D2 receptor 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
QPCT glutaminyl-peptide cyclotransferase
RABEP2 rabaptin, RAB GTPase binding effector protein 2
REC8 REC8 meiotic recombination protein
RGSL1 regulator of G-protein signaling like 1
RPL18 ribosomal protein L18
RPS4Y1 ribosomal protein S4, Y-linked 1
RSU1 Ras suppressor protein 1
RUNX1 runt-related transcription factor 1
SCN3B sodium channel, voltage gated, type III beta subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLITRK3 SLIT and NTRK-like family, member 3
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOGA1 suppressor of glucose, autophagy associated 1
SPEF1 sperm flagellar 1
SPRR2B small proline-rich protein 2B
SYNJ2 synaptojanin 2
SYT11 synaptotagmin XI
TAPBP TAP binding protein (tapasin)
THY1 Thy-1 cell surface antigen
TK2 thymidine kinase 2, mitochondrial
TLR5 toll-like receptor 5
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPP1 tripeptidyl peptidase I
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TTC38 tetratricopeptide repeat domain 38
TTLL3 tubulin tyrosine ligase-like family member 3
TXK TXK tyrosine kinase
VIPR1 vasoactive intestinal peptide receptor 1
ZNF407 zinc finger protein 407
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADAP2 ArfGAP with dual PH domains 2
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BIRC3 baculoviral IAP repeat containing 3
C11ORF63 chromosome 11 open reading frame 63
C17ORF53 chromosome 17 open reading frame 53
CA9 carbonic anhydrase IX
CADPS2 Ca++-dependent secretion activator 2
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CAPN15 calpain 15
CBX8 chromobox homolog 8
CCDC106 coiled-coil domain containing 106
CHMP6 charged multivesicular body protein 6
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL6 chemokine (C-X-C motif) ligand 6
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFNA3 ephrin-A3
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHA4 EPH receptor A4
FAM188A family with sequence similarity 188, member A
FAM50B family with sequence similarity 50, member B
GAL3ST4 galactose-3-O-sulfotransferase 4
GALK1 galactokinase 1
GBX2 gastrulation brain homeobox 2
GJC1 gap junction protein, gamma 1, 45kDa
GPR1 G protein-coupled receptor 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
HAS2 hyaluronan synthase 2
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IL17RB interleukin 17 receptor B
IL33 interleukin 33
IL6 interleukin 6
IL7R interleukin 7 receptor
KRT15 keratin 15, type I
LHX6 LIM homeobox 6
LRRC61 leucine rich repeat containing 61
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAL mal, T-cell differentiation protein
MEIS3P1 Meis homeobox 3 pseudogene 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MLYCD malonyl-CoA decarboxylase
MMP3 matrix metallopeptidase 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MT1M metallothionein 1M
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL6 nucleolar protein 6 (RNA-associated)
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
OSGIN1 oxidative stress induced growth inhibitor 1
POLM polymerase (DNA directed), mu
PRPH peripherin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RHOBTB1 Rho-related BTB domain containing 1
RIPPLY3 ripply transcriptional repressor 3
RNF146 ring finger protein 146
RNF31 ring finger protein 31
RPA4 replication protein A4, 30kDa
RPL13P5 ribosomal protein L13 pseudogene 5
RPP25 ribonuclease P/MRP 25kDa subunit
SCARA3 scavenger receptor class A, member 3
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLITRK5 SLIT and NTRK-like family, member 5
SMO smoothened, frizzled class receptor
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
TFCP2L1 transcription factor CP2-like 1
TLR2 toll-like receptor 2
TMEM121 transmembrane protein 121
TMEM209 transmembrane protein 209
TMEM40 transmembrane protein 40
TPST2 tyrosylprotein sulfotransferase 2
TSKU tsukushi, small leucine rich proteoglycan
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR4 WD repeat domain 4
WNT7A wingless-type MMTV integration site family, member 7A
ZNF215 zinc finger protein 215
ZNF350 zinc finger protein 350
ZNF510 zinc finger protein 510
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768