dilazep-7364 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dilazep-7364 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADCY6 adenylate cyclase 6
AIM1L absent in melanoma 1-like
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASB1 ankyrin repeat and SOCS box containing 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
C4ORF29 chromosome 4 open reading frame 29
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALML4 calmodulin-like 4
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC7 coiled-coil domain containing 7
CDC42 cell division cycle 42
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CIDEC cell death-inducing DFFA-like effector c
CLDN11 claudin 11
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCTN1 dynactin 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EPHB2 EPH receptor B2
ETV1 ets variant 1
FBXL7 F-box and leucine-rich repeat protein 7
FGF13 fibroblast growth factor 13
FGFR2 fibroblast growth factor receptor 2
FMO5 flavin containing monooxygenase 5
FZD1 frizzled class receptor 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GTPBP1 GTP binding protein 1
HIST1H2BG histone cluster 1, H2bg
HIST1H3H histone cluster 1, H3h
HIST3H2A histone cluster 3, H2a
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMHA1 histocompatibility (minor) HA-1
HOXC4 homeobox C4
HRK harakiri, BCL2 interacting protein
INSIG1 insulin induced gene 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIAA0319L KIAA0319-like
LDLR low density lipoprotein receptor
LGMN legumain
LOC157562 uncharacterized LOC157562
LPIN1 lipin 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK4 MAP/microtubule affinity-regulating kinase 4
METTL7A methyltransferase like 7A
MRPL57 mitochondrial ribosomal protein L57
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OPTN optineurin
PGAP1 post-GPI attachment to proteins 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLAG1 pleiomorphic adenoma gene 1
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRPH peripherin
PRUNE2 prune homolog 2 (Drosophila)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRE protein tyrosine phosphatase, receptor type, E
PVT1 Pvt1 oncogene (non-protein coding)
RAB6A RAB6A, member RAS oncogene family
RBMS3 RNA binding motif, single stranded interacting protein 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAIN RPA interacting protein
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRBP1 ribosome binding protein 1
SAMD4A sterile alpha motif domain containing 4A
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SMG7 SMG7 nonsense mediated mRNA decay factor
SND1-IT1 SND1 intronic transcript 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SREBF2 sterol regulatory element binding transcription factor 2
STARD3 StAR-related lipid transfer (START) domain containing 3
TAOK1 TAO kinase 1
TBCD tubulin folding cofactor D
TDRKH tudor and KH domain containing
TESK2 testis-specific kinase 2
TEX261 testis expressed 261
TMEM242 transmembrane protein 242
TRIM14 tripartite motif containing 14
TWF1 twinfilin actin binding protein 1
TXNRD3 thioredoxin reductase 3
UBE3B ubiquitin protein ligase E3B
UBN1 ubinuclein 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZBTB40 zinc finger and BTB domain containing 40
ZC2HC1C zinc finger, C2HC-type containing 1C
ZDHHC14 zinc finger, DHHC-type containing 14
ZER1 zyg-11 related, cell cycle regulator
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF277 zinc finger protein 277
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ALPK1 alpha-kinase 1
APLP1 amyloid beta (A4) precursor-like protein 1
BAHD1 bromo adjacent homology domain containing 1
BAK1 BCL2-antagonist/killer 1
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC3 baculoviral IAP repeat containing 3
C11ORF80 chromosome 11 open reading frame 80
C16ORF59 chromosome 16 open reading frame 59
C1ORF106 chromosome 1 open reading frame 106
CAPN15 calpain 15
CBX7 chromobox homolog 7
CCDC106 coiled-coil domain containing 106
CDH7 cadherin 7, type 2
CDON cell adhesion associated, oncogene regulated
CLCF1 cardiotrophin-like cytokine factor 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLL3 delta-like 3 (Drosophila)
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DUSP8 dual specificity phosphatase 8
ECM1 extracellular matrix protein 1
ELP6 elongator acetyltransferase complex subunit 6
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM155A family with sequence similarity 155, member A
FAM188A family with sequence similarity 188, member A
GRWD1 glutamate-rich WD repeat containing 1
HAS2 hyaluronan synthase 2
HOMER2 homer scaffolding protein 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL24 interleukin 24
IL6 interleukin 6
INHBA inhibin, beta A
KATNBL1 katanin p80 subunit B-like 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD15 potassium channel tetramerization domain containing 15
KIF16B kinesin family member 16B
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL3 kelch-like family member 3
LMNB1 lamin B1
LPAR6 lysophosphatidic acid receptor 6
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP5 low density lipoprotein receptor-related protein 5
MCRS1 microspherule protein 1
MED22 mediator complex subunit 22
MFGE8 milk fat globule-EGF factor 8 protein
MPI mannose phosphate isomerase
MYO1D myosin ID
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPR3 natriuretic peptide receptor 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
ODF2 outer dense fiber of sperm tails 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PARD6A par-6 family cell polarity regulator alpha
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PELP1 proline, glutamate and leucine rich protein 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLA2G15 phospholipase A2, group XV
PMEPA1 prostate transmembrane protein, androgen induced 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PTGFR prostaglandin F receptor (FP)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RECQL4 RecQ protein-like 4
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCAI suppressor of cancer cell invasion
SCEL sciellin
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETBP1 SET binding protein 1
SH2D4A SH2 domain containing 4A
SIRT6 sirtuin 6
SLC25A40 solute carrier family 25, member 40
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMA4 glucuronidase, beta pseudogene
SMAD7 SMAD family member 7
ST5 suppression of tumorigenicity 5
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TMEM183A transmembrane protein 183A
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNS2 tensin 2
WDR4 WD repeat domain 4
ZMYM3 zinc finger, MYM-type 3
ZNF204P zinc finger protein 204, pseudogene
ZNF350 zinc finger protein 350
ZNF354A zinc finger protein 354A
ZNF629 zinc finger protein 629