| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the dilazep-7364 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ADCY6 | adenylate cyclase 6 |
| AIM1L | absent in melanoma 1-like |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CALML4 | calmodulin-like 4 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC7 | coiled-coil domain containing 7 |
| CDC42 | cell division cycle 42 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLDN11 | claudin 11 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| DCTN1 | dynactin 1 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EPHB2 | EPH receptor B2 |
| ETV1 | ets variant 1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF13 | fibroblast growth factor 13 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FMO5 | flavin containing monooxygenase 5 |
| FZD1 | frizzled class receptor 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GTPBP1 | GTP binding protein 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3H | histone cluster 1, H3h |
| HIST3H2A | histone cluster 3, H2a |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC4 | homeobox C4 |
| HRK | harakiri, BCL2 interacting protein |
| INSIG1 | insulin induced gene 1 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KIAA0319L | KIAA0319-like |
| LDLR | low density lipoprotein receptor |
| LGMN | legumain |
| LOC157562 | uncharacterized LOC157562 |
| LPIN1 | lipin 1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| METTL7A | methyltransferase like 7A |
| MRPL57 | mitochondrial ribosomal protein L57 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| OPTN | optineurin |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRPH | peripherin |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB6A | RAB6A, member RAS oncogene family |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPAIN | RPA interacting protein |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RRBP1 | ribosome binding protein 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TAOK1 | TAO kinase 1 |
| TBCD | tubulin folding cofactor D |
| TDRKH | tudor and KH domain containing |
| TESK2 | testis-specific kinase 2 |
| TEX261 | testis expressed 261 |
| TMEM242 | transmembrane protein 242 |
| TRIM14 | tripartite motif containing 14 |
| TWF1 | twinfilin actin binding protein 1 |
| TXNRD3 | thioredoxin reductase 3 |
| UBE3B | ubiquitin protein ligase E3B |
| UBN1 | ubinuclein 1 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF277 | zinc finger protein 277 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ALPK1 | alpha-kinase 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| CAPN15 | calpain 15 |
| CBX7 | chromobox homolog 7 |
| CCDC106 | coiled-coil domain containing 106 |
| CDH7 | cadherin 7, type 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DLL3 | delta-like 3 (Drosophila) |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DUSP8 | dual specificity phosphatase 8 |
| ECM1 | extracellular matrix protein 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV4 | ets variant 4 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM155A | family with sequence similarity 155, member A |
| FAM188A | family with sequence similarity 188, member A |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HAS2 | hyaluronan synthase 2 |
| HOMER2 | homer scaffolding protein 2 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL24 | interleukin 24 |
| IL6 | interleukin 6 |
| INHBA | inhibin, beta A |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIF16B | kinesin family member 16B |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL3 | kelch-like family member 3 |
| LMNB1 | lamin B1 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MCRS1 | microspherule protein 1 |
| MED22 | mediator complex subunit 22 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MPI | mannose phosphate isomerase |
| MYO1D | myosin ID |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NPR3 | natriuretic peptide receptor 3 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLA2G15 | phospholipase A2, group XV |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PTGFR | prostaglandin F receptor (FP) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RECQL4 | RecQ protein-like 4 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SCAI | suppressor of cancer cell invasion |
| SCEL | sciellin |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETBP1 | SET binding protein 1 |
| SH2D4A | SH2 domain containing 4A |
| SIRT6 | sirtuin 6 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMAD7 | SMAD family member 7 |
| ST5 | suppression of tumorigenicity 5 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLN1 | talin 1 |
| TMEM183A | transmembrane protein 183A |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNS2 | tensin 2 |
| WDR4 | WD repeat domain 4 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF350 | zinc finger protein 350 |
| ZNF354A | zinc finger protein 354A |
| ZNF629 | zinc finger protein 629 |