| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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190 genes differentially expressed following the diloxanide-3062 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE | angiotensin I converting enzyme |
| ACOXL | acyl-CoA oxidase-like |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADRB1 | adrenoceptor beta 1 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| APOA4 | apolipoprotein A-IV |
| ARTN | artemin |
| ATP10B | ATPase, class V, type 10B |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| ATP9A | ATPase, class II, type 9A |
| C7ORF26 | chromosome 7 open reading frame 26 |
| C9ORF116 | chromosome 9 open reading frame 116 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CDK2 | cyclin-dependent kinase 2 |
| CHGA | chromogranin A |
| CLEC10A | C-type lectin domain family 10, member A |
| COL5A1 | collagen, type V, alpha 1 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CRYBB1 | crystallin, beta B1 |
| CSN2 | casein beta |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DMC1 | DNA meiotic recombinase 1 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| EPB41 | erythrocyte membrane protein band 4.1 |
| EXT1 | exostosin glycosyltransferase 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FSTL4 | follistatin-like 4 |
| GLRA2 | glycine receptor, alpha 2 |
| GPR35 | G protein-coupled receptor 35 |
| HES1 | hes family bHLH transcription factor 1 |
| HOXD13 | homeobox D13 |
| HRG | histidine-rich glycoprotein |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IL1RN | interleukin 1 receptor antagonist |
| ITGB8 | integrin, beta 8 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF1A | kinesin family member 1A |
| KIF1C | kinesin family member 1C |
| KLC2 | kinesin light chain 2 |
| KRT14 | keratin 14, type I |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAMA3 | laminin, alpha 3 |
| LARGE | like-glycosyltransferase |
| LHX1 | LIM homeobox 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL1 | lysyl oxidase-like 1 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAPT | microtubule-associated protein tau |
| MCF2 | MCF.2 cell line derived transforming sequence |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MOXD1 | monooxygenase, DBH-like 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MYLK | myosin light chain kinase |
| NMUR1 | neuromedin U receptor 1 |
| NRG1 | neuregulin 1 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PDE11A | phosphodiesterase 11A |
| PKP3 | plakophilin 3 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRM1 | protamine 1 |
| PRM2 | protamine 2 |
| PVR | poliovirus receptor |
| RBBP4 | retinoblastoma binding protein 4 |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| REG1A | regenerating islet-derived 1 alpha |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RPL10L | ribosomal protein L10-like |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SOX5 | SRY (sex determining region Y)-box 5 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| ST8SIA1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TSHR | thyroid stimulating hormone receptor |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZNF259P1 | zinc finger protein 259 pseudogene 1 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ALS2CL | ALS2 C-terminal like |
| AMDHD2 | amidohydrolase domain containing 2 |
| AMPH | amphiphysin |
| ANKRD55 | ankyrin repeat domain 55 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATG10 | autophagy related 10 |
| BAG4 | BCL2-associated athanogene 4 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| C4BPA | complement component 4 binding protein, alpha |
| CCDC186 | coiled-coil domain containing 186 |
| CD300C | CD300c molecule |
| CD37 | CD37 molecule |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EMILIN2 | elastin microfibril interfacer 2 |
| EXO5 | exonuclease 5 |
| FAM131A | family with sequence similarity 131, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FHL3 | four and a half LIM domains 3 |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FOXN2 | forkhead box N2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPATCH2L | G patch domain containing 2-like |
| GPC3 | glypican 3 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H1B | histone cluster 1, H1b |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| INCENP | inner centromere protein antigens 135/155kDa |
| KIAA0753 | KIAA0753 |
| KLHL21 | kelch-like family member 21 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYBPH | myosin binding protein H |
| NABP1 | nucleic acid binding protein 1 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOL10 | nucleolar protein 10 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PER3 | period circadian clock 3 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PROCR | protein C receptor, endothelial |
| PROS1 | protein S (alpha) |
| QSER1 | glutamine and serine rich 1 |
| RAB17 | RAB17, member RAS oncogene family |
| RASAL2 | RAS protein activator like 2 |
| RHOB | ras homolog family member B |
| S100A12 | S100 calcium binding protein A12 |
| SCG5 | secretogranin V |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLAMF7 | SLAM family member 7 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNX15 | sorting nexin 15 |
| SPATA20 | spermatogenesis associated 20 |
| SPATA2L | spermatogenesis associated 2-like |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| STAP1 | signal transducing adaptor family member 1 |
| STATH | statherin |
| SYCP2 | synaptonemal complex protein 2 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TCTA | T-cell leukemia translocation altered |
| TEC | tec protein tyrosine kinase |
| THEM6 | thioesterase superfamily member 6 |
| TMEM242 | transmembrane protein 242 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBB2A | tubulin, beta 2A class IIa |
| USB1 | U6 snRNA biogenesis 1 |
| USP53 | ubiquitin specific peptidase 53 |
| WASF3 | WAS protein family, member 3 |
| WDR62 | WD repeat domain 62 |
| ZNF219 | zinc finger protein 219 |
| ZNF492 | zinc finger protein 492 |
| ZNF768 | zinc finger protein 768 |