diloxanide-3062 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

190 genes differentially expressed following the diloxanide-3062 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
ACOXL acyl-CoA oxidase-like
ACTA2 actin, alpha 2, smooth muscle, aorta
ADRB1 adrenoceptor beta 1
AKAP6 A kinase (PRKA) anchor protein 6
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALOX15B arachidonate 15-lipoxygenase, type B
APOA4 apolipoprotein A-IV
ARTN artemin
ATP10B ATPase, class V, type 10B
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP9A ATPase, class II, type 9A
C7ORF26 chromosome 7 open reading frame 26
C9ORF116 chromosome 9 open reading frame 116
CCL22 chemokine (C-C motif) ligand 22
CCR7 chemokine (C-C motif) receptor 7
CDK2 cyclin-dependent kinase 2
CHGA chromogranin A
CLEC10A C-type lectin domain family 10, member A
COL5A1 collagen, type V, alpha 1
CRISP2 cysteine-rich secretory protein 2
CRYBB1 crystallin, beta B1
CSN2 casein beta
CXCL3 chemokine (C-X-C motif) ligand 3
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DMC1 DNA meiotic recombinase 1
DNALI1 dynein, axonemal, light intermediate chain 1
EPB41 erythrocyte membrane protein band 4.1
EXT1 exostosin glycosyltransferase 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FGFR2 fibroblast growth factor receptor 2
FSTL4 follistatin-like 4
GLRA2 glycine receptor, alpha 2
GPR35 G protein-coupled receptor 35
HES1 hes family bHLH transcription factor 1
HOXD13 homeobox D13
HRG histidine-rich glycoprotein
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IL1RN interleukin 1 receptor antagonist
ITGB8 integrin, beta 8
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF1A kinesin family member 1A
KIF1C kinesin family member 1C
KLC2 kinesin light chain 2
KRT14 keratin 14, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMA3 laminin, alpha 3
LARGE like-glycosyltransferase
LHX1 LIM homeobox 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOXL1 lysyl oxidase-like 1
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPT microtubule-associated protein tau
MCF2 MCF.2 cell line derived transforming sequence
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MOXD1 monooxygenase, DBH-like 1
MTCP1 mature T-cell proliferation 1
MYLK myosin light chain kinase
NMUR1 neuromedin U receptor 1
NRG1 neuregulin 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PBOV1 prostate and breast cancer overexpressed 1
PDE11A phosphodiesterase 11A
PKP3 plakophilin 3
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRM1 protamine 1
PRM2 protamine 2
PVR poliovirus receptor
RBBP4 retinoblastoma binding protein 4
RBM12B-AS1 RBM12B antisense RNA 1
REG1A regenerating islet-derived 1 alpha
RIBC2 RIB43A domain with coiled-coils 2
RIPPLY3 ripply transcriptional repressor 3
RPL10L ribosomal protein L10-like
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOX5 SRY (sex determining region Y)-box 5
SPTBN5 spectrin, beta, non-erythrocytic 5
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
TCAF1 TRPM8 channel-associated factor 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TSHR thyroid stimulating hormone receptor
WNT1 wingless-type MMTV integration site family, member 1
WNT8B wingless-type MMTV integration site family, member 8B
ZNF259P1 zinc finger protein 259 pseudogene 1

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ALS2CL ALS2 C-terminal like
AMDHD2 amidohydrolase domain containing 2
AMPH amphiphysin
ANKRD55 ankyrin repeat domain 55
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARR3 arrestin 3, retinal (X-arrestin)
ATG10 autophagy related 10
BAG4 BCL2-associated athanogene 4
BGLAP bone gamma-carboxyglutamate (gla) protein
BHMT2 betaine--homocysteine S-methyltransferase 2
C4BPA complement component 4 binding protein, alpha
CCDC186 coiled-coil domain containing 186
CD300C CD300c molecule
CD37 CD37 molecule
CDY1 chromodomain protein, Y-linked, 1
CECR1 cat eye syndrome chromosome region, candidate 1
CLEC4E C-type lectin domain family 4, member E
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAH17 dynein, axonemal, heavy chain 17
DTX2 deltex 2, E3 ubiquitin ligase
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EMILIN2 elastin microfibril interfacer 2
EXO5 exonuclease 5
FAM131A family with sequence similarity 131, member A
FBXL7 F-box and leucine-rich repeat protein 7
FHL3 four and a half LIM domains 3
FKBP9 FK506 binding protein 9, 63 kDa
FOXN2 forkhead box N2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
GIF gastric intrinsic factor (vitamin B synthesis)
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPATCH2L G patch domain containing 2-like
GPC3 glypican 3
GTF2IRD1 GTF2I repeat domain containing 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1B histone cluster 1, H1b
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INCENP inner centromere protein antigens 135/155kDa
KIAA0753 KIAA0753
KLHL21 kelch-like family member 21
LTBP2 latent transforming growth factor beta binding protein 2
LZTR1 leucine-zipper-like transcription regulator 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYBPH myosin binding protein H
NABP1 nucleic acid binding protein 1
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NFE2L3 nuclear factor, erythroid 2-like 3
NOL10 nucleolar protein 10
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PARP16 poly (ADP-ribose) polymerase family, member 16
PER3 period circadian clock 3
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
QSER1 glutamine and serine rich 1
RAB17 RAB17, member RAS oncogene family
RASAL2 RAS protein activator like 2
RHOB ras homolog family member B
S100A12 S100 calcium binding protein A12
SCG5 secretogranin V
SCGB2A2 secretoglobin, family 2A, member 2
SLAMF7 SLAM family member 7
SLC17A2 solute carrier family 17, member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35F6 solute carrier family 35, member F6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNX15 sorting nexin 15
SPATA20 spermatogenesis associated 20
SPATA2L spermatogenesis associated 2-like
SPINT1 serine peptidase inhibitor, Kunitz type 1
SSBP3 single stranded DNA binding protein 3
STAP1 signal transducing adaptor family member 1
STATH statherin
SYCP2 synaptonemal complex protein 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCTA T-cell leukemia translocation altered
TEC tec protein tyrosine kinase
THEM6 thioesterase superfamily member 6
TMEM242 transmembrane protein 242
TRPS1 trichorhinophalangeal syndrome I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC30A tetratricopeptide repeat domain 30A
TUBB2A tubulin, beta 2A class IIa
USB1 U6 snRNA biogenesis 1
USP53 ubiquitin specific peptidase 53
WASF3 WAS protein family, member 3
WDR62 WD repeat domain 62
ZNF219 zinc finger protein 219
ZNF492 zinc finger protein 492
ZNF768 zinc finger protein 768