diloxanide-3399 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the diloxanide-3399 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRL1 adhesion G protein-coupled receptor L1
AIRE autoimmune regulator
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARID5A AT rich interactive domain 5A (MRF1-like)
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
C17ORF53 chromosome 17 open reading frame 53
C22ORF46 chromosome 22 open reading frame 46
C2CD2L C2CD2-like
CA1 carbonic anhydrase I
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD84 CD84 molecule
CD8A CD8a molecule
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CNTN1 contactin 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYSLTR2 cysteinyl leukotriene receptor 2
DGCR8 DGCR8 microprocessor complex subunit
DKFZP434C153 DKFZP434C153 protein
DNASE1L2 deoxyribonuclease I-like 2
EAF2 ELL associated factor 2
EPS8L3 EPS8-like 3
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
FBXO4 F-box protein 4
FGFBP1 fibroblast growth factor binding protein 1
FHL1 four and a half LIM domains 1
FMOD fibromodulin
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GM2A GM2 ganglioside activator
GPR3 G protein-coupled receptor 3
GREB1L growth regulation by estrogen in breast cancer-like
GRIK5 glutamate receptor, ionotropic, kainate 5
GRPR gastrin-releasing peptide receptor
GSTP1 glutathione S-transferase pi 1
HDLBP high density lipoprotein binding protein
HIPK2 homeodomain interacting protein kinase 2
HLF hepatic leukemia factor
IL17RC interleukin 17 receptor C
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL36R interleukin 36 receptor
ING2 inhibitor of growth family, member 2
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGA8 integrin, alpha 8
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF5A kinesin family member 5A
KRT20 keratin 20, type I
KRT37 keratin 37, type I
KRT8 keratin 8, type II
LEPR leptin receptor
LTK leukocyte receptor tyrosine kinase
MALL mal, T-cell differentiation protein-like
MAP1A microtubule-associated protein 1A
MAP2 microtubule-associated protein 2
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIIP migration and invasion inhibitory protein
MRPL41 mitochondrial ribosomal protein L41
MTA2 metastasis associated 1 family, member 2
MYL10 myosin, light chain 10, regulatory
NEUROD2 neuronal differentiation 2
NRF1 nuclear respiratory factor 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NXPH3 neurexophilin 3
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PIP prolactin-induced protein
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG3 pregnancy specific beta-1-glycoprotein 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SARM1 sterile alpha and TIR motif containing 1
SIPA1 signal-induced proliferation-associated 1
SIRPB1 signal-regulatory protein beta 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SOCS3 suppressor of cytokine signaling 3
SPRR1A small proline-rich protein 1A
SRSF7 serine/arginine-rich splicing factor 7
STS steroid sulfatase (microsomal), isozyme S
SYNDIG1 synapse differentiation inducing 1
TAC3 tachykinin 3
TBXA2R thromboxane A2 receptor
THY1 Thy-1 cell surface antigen
TJAP1 tight junction associated protein 1 (peripheral)
TMEM212 transmembrane protein 212
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UNC5B unc-5 homolog B (C. elegans)
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF155 zinc finger protein 155
ZNF646 zinc finger protein 646
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AHNAK2 AHNAK nucleoprotein 2
ANKH ANKH inorganic pyrophosphate transport regulator
APOLD1 apolipoprotein L domain containing 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
AUTS2 autism susceptibility candidate 2
C14ORF79 chromosome 14 open reading frame 79
C5AR1 complement component 5a receptor 1
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAPN5 calpain 5
CD79B CD79b molecule, immunoglobulin-associated beta
CDON cell adhesion associated, oncogene regulated
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CLEC4E C-type lectin domain family 4, member E
CLGN calmegin
CNPY4 canopy FGF signaling regulator 4
CRIP1 cysteine-rich protein 1 (intestinal)
CRY2 cryptochrome circadian clock 2
CUZD1 CUB and zona pellucida-like domains 1
DMTN dematin actin binding protein
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNM3 dynamin 3
DUSP13 dual specificity phosphatase 13
DYM dymeclin
EMID1 EMI domain containing 1
FAM131A family with sequence similarity 131, member A
FAM155A family with sequence similarity 155, member A
FSCN3 fascin actin-bundling protein 3, testicular
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GLDC glycine dehydrogenase (decarboxylating)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2BC histone cluster 1, H2bc
HIST1H4E histone cluster 1, H4e
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HYAL3 hyaluronoglucosaminidase 3
IMPG2 interphotoreceptor matrix proteoglycan 2
INO80D INO80 complex subunit D
INSIG2 insulin induced gene 2
ITPKA inositol-trisphosphate 3-kinase A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LOC157562 uncharacterized LOC157562
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MEFV Mediterranean fever
MSI1 musashi RNA-binding protein 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NKX3-2 NK3 homeobox 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NT5DC3 5'-nucleotidase domain containing 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OXCT2 3-oxoacid CoA transferase 2
PADI1 peptidyl arginine deiminase, type I
PALM paralemmin
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PDIA3 protein disulfide isomerase family A, member 3
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMEL premelanosome protein
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QPCT glutaminyl-peptide cyclotransferase
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARS arginyl-tRNA synthetase
RHOBTB2 Rho-related BTB domain containing 2
RND1 Rho family GTPase 1
RNF43 ring finger protein 43
RPAP1 RNA polymerase II associated protein 1
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCARA3 scavenger receptor class A, member 3
SCN1B sodium channel, voltage gated, type I beta subunit
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC16A4 solute carrier family 16, member 4
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SOX3 SRY (sex determining region Y)-box 3
SPRR2B small proline-rich protein 2B
SSTR4 somatostatin receptor 4
TBKBP1 TBK1 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCP10 t-complex 10
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TICAM1 toll-like receptor adaptor molecule 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPRSS4 transmembrane protease, serine 4
TUBA3C tubulin, alpha 3c
ZDHHC14 zinc finger, DHHC-type containing 14
ZFHX4 zinc finger homeobox 4
ZNF286A zinc finger protein 286A