| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the diltiazem-1948 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGAP32 | Rho GTPase activating protein 32 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| CALR | calreticulin |
| CBX6 | chromobox homolog 6 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| COPS7B | COP9 signalosome subunit 7B |
| COX7C | cytochrome c oxidase subunit VIIc |
| CRYM | crystallin, mu |
| DENND2A | DENN/MADD domain containing 2A |
| DUSP6 | dual specificity phosphatase 6 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 |
| EFNA1 | ephrin-A1 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FAM174B | family with sequence similarity 174, member B |
| GLRX3 | glutaredoxin 3 |
| HEATR6 | HEAT repeat containing 6 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HOXD9 | homeobox D9 |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| JUNB | jun B proto-oncogene |
| KLHL24 | kelch-like family member 24 |
| KRT81 | keratin 81, type II |
| LRRC61 | leucine rich repeat containing 61 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MECP2 | methyl CpG binding protein 2 |
| MICALL1 | MICAL-like 1 |
| MKS1 | Meckel syndrome, type 1 |
| MRPL9 | mitochondrial ribosomal protein L9 |
| MSH3 | mutS homolog 3 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NAP1L1 | nucleosome assembly protein 1-like 1 |
| NKIRAS2 | NFKB inhibitor interacting Ras-like 2 |
| OLFML2A | olfactomedin-like 2A |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLSCR3 | phospholipid scramblase 3 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRDM14 | PR domain containing 14 |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RGS16 | regulator of G-protein signaling 16 |
| RPL23A | ribosomal protein L23a |
| RPL27A | ribosomal protein L27a |
| RPL34 | ribosomal protein L34 |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| RPL7 | ribosomal protein L7 |
| RPLP0 | ribosomal protein, large, P0 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS10 | ribosomal protein S10 |
| RPS11 | ribosomal protein S11 |
| RPSA | ribosomal protein SA |
| RUSC2 | RUN and SH3 domain containing 2 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SFTPB | surfactant protein B |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SMC3 | structural maintenance of chromosomes 3 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SMYD5 | SMYD family member 5 |
| SUGP1 | SURP and G patch domain containing 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TMEM161A | transmembrane protein 161A |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TPMT | thiopurine S-methyltransferase |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TXN | thioredoxin |
| UNKL | unkempt family zinc finger-like |
| UQCRB | ubiquinol-cytochrome c reductase binding protein |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WSCD1 | WSC domain containing 1 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF580 | zinc finger protein 580 |
| ZNF747 | zinc finger protein 747 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| APOO | apolipoprotein O |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BMS1 | BMS1 ribosome biogenesis factor |
| BNC2 | basonuclin 2 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C12ORF49 | chromosome 12 open reading frame 49 |
| C1GALT1C1 | C1GALT1-specific chaperone 1 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 |
| CCDC28A | coiled-coil domain containing 28A |
| CCDC47 | coiled-coil domain containing 47 |
| CDC73 | cell division cycle 73 |
| CEP170B | centrosomal protein 170B |
| CISH | cytokine inducible SH2-containing protein |
| CLGN | calmegin |
| CNTNAP1 | contactin associated protein 1 |
| CPOX | coproporphyrinogen oxidase |
| CRIP2 | cysteine-rich protein 2 |
| CROT | carnitine O-octanoyltransferase |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DCTN4 | dynactin 4 (p62) |
| DDB1 | damage-specific DNA binding protein 1, 127kDa |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DPYD | dihydropyrimidine dehydrogenase |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM193B | family with sequence similarity 193, member B |
| FAM35A | family with sequence similarity 35, member A |
| FAM53B | family with sequence similarity 53, member B |
| FPGS | folylpolyglutamate synthase |
| FPGT | fucose-1-phosphate guanylyltransferase |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| FXN | frataxin |
| FZD6 | frizzled class receptor 6 |
| GBAS | glioblastoma amplified sequence |
| GCA | grancalcin, EF-hand calcium binding protein |
| GIN1 | gypsy retrotransposon integrase 1 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
| HIST1H2BC | histone cluster 1, H2bc |
| HOOK2 | hook microtubule-tethering protein 2 |
| HOXA5 | homeobox A5 |
| IFNA17 | interferon, alpha 17 |
| IFT88 | intraflagellar transport 88 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KIFC1 | kinesin family member C1 |
| KLHDC4 | kelch domain containing 4 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LETMD1 | LETM1 domain containing 1 |
| LYRM2 | LYR motif containing 2 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCOLN1 | mucolipin 1 |
| MICU2 | mitochondrial calcium uptake 2 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NCSTN | nicastrin |
| OSBPL11 | oxysterol binding protein-like 11 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PARG | poly (ADP-ribose) glycohydrolase |
| PGD | phosphogluconate dehydrogenase |
| PGM3 | phosphoglucomutase 3 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTCD3 | pentatricopeptide repeat domain 3 |
| RAB20 | RAB20, member RAS oncogene family |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RBBP5 | retinoblastoma binding protein 5 |
| RELN | reelin |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase |
| RNF167 | ring finger protein 167 |
| RPP14 | ribonuclease P/MRP 14kDa subunit |
| SDAD1 | SDA1 domain containing 1 |
| SEC24B | SEC24 family member B |
| SELT | selenoprotein T |
| SFT2D2 | SFT2 domain containing 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SMYD3 | SET and MYND domain containing 3 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMEM184C | transmembrane protein 184C |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| USP8 | ubiquitin specific peptidase 8 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| WBP2 | WW domain binding protein 2 |
| WRN | Werner syndrome, RecQ helicase-like |
| ZNF175 | zinc finger protein 175 |
| ZNF85 | zinc finger protein 85 |
