| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the diltiazem-2032 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ACVRL1 | activin A receptor type II-like 1 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATG4B | autophagy related 4B, cysteine peptidase |
| ATN1 | atrophin 1 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| CCDC40 | coiled-coil domain containing 40 |
| CDK13 | cyclin-dependent kinase 13 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CLDN10 | claudin 10 |
| COL10A1 | collagen, type X, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CREM | cAMP responsive element modulator |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DSCR3 | Down syndrome critical region 3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ELMO2 | engulfment and cell motility 2 |
| EPHB2 | EPH receptor B2 |
| EPS8L1 | EPS8-like 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FBXO42 | F-box protein 42 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FSCN1 | fascin actin-bundling protein 1 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR107 | G protein-coupled receptor 107 |
| GPX2 | glutathione peroxidase 2 |
| HIST1H2BI | histone cluster 1, H2bi |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HNF1A | HNF1 homeobox A |
| HOXB5 | homeobox B5 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| HTRA1 | HtrA serine peptidase 1 |
| IFNA17 | interferon, alpha 17 |
| IFT27 | intraflagellar transport 27 |
| IGF1R | insulin-like growth factor 1 receptor |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KLHL12 | kelch-like family member 12 |
| LAD1 | ladinin 1 |
| LENEP | lens epithelial protein |
| LTB4R | leukotriene B4 receptor |
| LUZP1 | leucine zipper protein 1 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAX | MYC associated factor X |
| MED16 | mediator complex subunit 16 |
| MEF2C | myocyte enhancer factor 2C |
| METTL7A | methyltransferase like 7A |
| MPZ | myelin protein zero |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NADK | NAD kinase |
| NOTCH2 | notch 2 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| NXF2 | nuclear RNA export factor 2 |
| OCRL | oculocerebrorenal syndrome of Lowe |
| PALM | paralemmin |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLEC | plectin |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRSS22 | protease, serine, 22 |
| PRSS53 | protease, serine, 53 |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RGS1 | regulator of G-protein signaling 1 |
| RORC | RAR-related orphan receptor C |
| RPS11 | ribosomal protein S11 |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SFTPB | surfactant protein B |
| SH2D1A | SH2 domain containing 1A |
| SH3BP2 | SH3-domain binding protein 2 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SNTA1 | syntrophin, alpha 1 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SYT2 | synaptotagmin II |
| TBL1X | transducin (beta)-like 1X-linked |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| WIZ | widely interspaced zinc finger motifs |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZGPAT | zinc finger, CCCH-type with G patch domain |
| ZNF211 | zinc finger protein 211 |
| ZNF79 | zinc finger protein 79 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| AVEN | apoptosis, caspase activation inhibitor |
| AZI2 | 5-azacytidine induced 2 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C1D | C1D nuclear receptor corepressor |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CCDC6 | coiled-coil domain containing 6 |
| CD302 | CD302 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP72 | centrosomal protein 72kDa |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COCH | cochlin |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| COMMD8 | COMM domain containing 8 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) |
| CPOX | coproporphyrinogen oxidase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CTSD | cathepsin D |
| CYB5R3 | cytochrome b5 reductase 3 |
| DENND1B | DENN/MADD domain containing 1B |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| EMP3 | epithelial membrane protein 3 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| FAM222B | family with sequence similarity 222, member B |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FCHSD2 | FCH and double SH3 domains 2 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GLOD4 | glyoxalase domain containing 4 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 |
| GPN3 | GPN-loop GTPase 3 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HIRA | histone cell cycle regulator |
| HSPA4L | heat shock 70kDa protein 4-like |
| ITGAV | integrin, alpha V |
| JMJD4 | jumonji domain containing 4 |
| KIF20B | kinesin family member 20B |
| KIFC1 | kinesin family member C1 |
| KTN1 | kinectin 1 (kinesin receptor) |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 |
| LSM1 | LSM1, U6 small nuclear RNA associated |
| LYRM2 | LYR motif containing 2 |
| MAEA | macrophage erythroblast attacher |
| MAPK3 | mitogen-activated protein kinase 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| METTL18 | methyltransferase like 18 |
| MT1HL1 | metallothionein 1H-like 1 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| ORC2 | origin recognition complex, subunit 2 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PBK | PDZ binding kinase |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RARS | arginyl-tRNA synthetase |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RIOK2 | RIO kinase 2 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RWDD3 | RWD domain containing 3 |
| SERINC1 | serine incorporator 1 |
| SMNDC1 | survival motor neuron domain containing 1 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STK39 | serine threonine kinase 39 |
| TIPIN | TIMELESS interacting protein |
| TMEM14A | transmembrane protein 14A |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM168 | transmembrane protein 168 |
| TPCN1 | two pore segment channel 1 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TUBA1A | tubulin, alpha 1a |
| UBE3C | ubiquitin protein ligase E3C |
| VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZNF12 | zinc finger protein 12 |
| ZNF14 | zinc finger protein 14 |
| ZNF217 | zinc finger protein 217 |
| ZNF652 | zinc finger protein 652 |
| ZNF654 | zinc finger protein 654 |
| ZW10 | zw10 kinetochore protein |
