| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the diltiazem-5309 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AFAP1 | actin filament associated protein 1 |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| ALCAM | activated leukocyte cell adhesion molecule |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATP11A | ATPase, class VI, type 11A |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BCL9 | B-cell CLL/lymphoma 9 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C19ORF60 | chromosome 19 open reading frame 60 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CDHR1 | cadherin-related family member 1 |
| CDK19 | cyclin-dependent kinase 19 |
| CENPO | centromere protein O |
| CEP162 | centrosomal protein 162kDa |
| CIC | capicua transcriptional repressor |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DTNA | dystrobrevin, alpha |
| EGFR | epidermal growth factor receptor |
| ESR1 | estrogen receptor 1 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FBXO22 | F-box protein 22 |
| FBXO9 | F-box protein 9 |
| FER | fer (fps/fes related) tyrosine kinase |
| FNDC3A | fibronectin type III domain containing 3A |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GATA4 | GATA binding protein 4 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HDLBP | high density lipoprotein binding protein |
| HLA-B | major histocompatibility complex, class I, B |
| HNMT | histamine N-methyltransferase |
| ING4 | inhibitor of growth family, member 4 |
| IRF4 | interferon regulatory factor 4 |
| KIF1C | kinesin family member 1C |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LRRC20 | leucine rich repeat containing 20 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LYST | lysosomal trafficking regulator |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MAP4 | microtubule-associated protein 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MFN2 | mitofusin 2 |
| MIEF1 | mitochondrial elongation factor 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSTF1 | osteoclast stimulating factor 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCNX | pecanex homolog (Drosophila) |
| PDAP1 | PDGFA associated protein 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PLA2G3 | phospholipase A2, group III |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRDX2 | peroxiredoxin 2 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PRR4 | proline rich 4 (lacrimal) |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RBPMS | RNA binding protein with multiple splicing |
| RGS10 | regulator of G-protein signaling 10 |
| RNF19B | ring finger protein 19B |
| RNF2 | ring finger protein 2 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| ROM1 | retinal outer segment membrane protein 1 |
| S100A4 | S100 calcium binding protein A4 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STK38L | serine/threonine kinase 38 like |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TDRKH | tudor and KH domain containing |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TMEM259 | transmembrane protein 259 |
| TNS2 | tensin 2 |
| TPMT | thiopurine S-methyltransferase |
| TREX1 | three prime repair exonuclease 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBE3A | ubiquitin protein ligase E3A |
| USP34 | ubiquitin specific peptidase 34 |
| VAX2 | ventral anterior homeobox 2 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF24 | zinc finger protein 24 |
| ZNF304 | zinc finger protein 304 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD10 | ankyrin repeat domain 10 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| AXIN1 | axin 1 |
| BRD9 | bromodomain containing 9 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC6 | coiled-coil domain containing 6 |
| CCDC94 | coiled-coil domain containing 94 |
| CHPF | chondroitin polymerizing factor |
| CLSPN | claspin |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COL9A2 | collagen, type IX, alpha 2 |
| CTSV | cathepsin V |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DUSP5 | dual specificity phosphatase 5 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EVPL | envoplakin |
| FCHSD2 | FCH and double SH3 domains 2 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FOXC1 | forkhead box C1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GAA | glucosidase, alpha; acid |
| GAB2 | GRB2-associated binding protein 2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRAMD4 | GRAM domain containing 4 |
| HAUS7 | HAUS augmin-like complex, subunit 7 |
| HIRIP3 | HIRA interacting protein 3 |
| HTT | huntingtin |
| ILK | integrin-linked kinase |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| LAMA3 | laminin, alpha 3 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MED15 | mediator complex subunit 15 |
| MEIS1 | Meis homeobox 1 |
| MITF | microphthalmia-associated transcription factor |
| MMP9 | matrix metallopeptidase 9 |
| MXRA7 | matrix-remodelling associated 7 |
| MYO9A | myosin IXA |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POMZP3 | POM121 and ZP3 fusion |
| PP14571 | uncharacterized LOC100130449 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTK6 | protein tyrosine kinase 6 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF113A | ring finger protein 113A |
| RNF31 | ring finger protein 31 |
| SHPK | sedoheptulokinase |
| SIK1 | salt-inducible kinase 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPHK1 | sphingosine kinase 1 |
| SRSF4 | serine/arginine-rich splicing factor 4 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TDRD1 | tudor domain containing 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM39B | transmembrane protein 39B |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| USP21 | ubiquitin specific peptidase 21 |
| WWC2 | WW and C2 domain containing 2 |
| XAB2 | XPA binding protein 2 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF106 | zinc finger protein 106 |
| ZNF282 | zinc finger protein 282 |
| ZNF331 | zinc finger protein 331 |
| ZNF557 | zinc finger protein 557 |
| ZNF586 | zinc finger protein 586 |
| ZNF692 | zinc finger protein 692 |
| ZNF7 | zinc finger protein 7 |
| ZNF8 | zinc finger protein 8 |
| ZNF862 | zinc finger protein 862 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |