| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the diltiazem-6710 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ARL14 | ADP-ribosylation factor-like 14 |
| C5AR1 | complement component 5a receptor 1 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD209 | CD209 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| CLCA2 | chloride channel accessory 2 |
| COMT | catechol-O-methyltransferase |
| CTH | cystathionine gamma-lyase |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DICER1 | dicer 1, ribonuclease type III |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUX4L8 | double homeobox 4 like 8 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EMID1 | EMI domain containing 1 |
| ESR1 | estrogen receptor 1 |
| FAM149A | family with sequence similarity 149, member A |
| FOXO4 | forkhead box O4 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAN | gigaxonin |
| GAS7 | growth arrest-specific 7 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPR35 | G protein-coupled receptor 35 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HEMK1 | HemK methyltransferase family member 1 |
| HIST1H2AL | histone cluster 1, H2al |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IL11 | interleukin 11 |
| IL6 | interleukin 6 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KLK13 | kallikrein-related peptidase 13 |
| KRT14 | keratin 14, type I |
| KRTAP2-4 | keratin associated protein 2-4 |
| MAP7 | microtubule-associated protein 7 |
| MEGF6 | multiple EGF-like-domains 6 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTMR7 | myotubularin related protein 7 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NOX1 | NADPH oxidase 1 |
| NUP88 | nucleoporin 88kDa |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OCM2 | oncomodulin 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE10A | phosphodiesterase 10A |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 |
| PLXNB3 | plexin B3 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRDM12 | PR domain containing 12 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRTN3 | proteinase 3 |
| PTGES | prostaglandin E synthase |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| REG1P | regenerating islet-derived 1 pseudogene |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL14 | ribosomal protein L14 |
| RPLP2 | ribosomal protein, large, P2 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SOSTDC1 | sclerostin domain containing 1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STC1 | stanniocalcin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TDRD12 | tudor domain containing 12 |
| TSKS | testis-specific serine kinase substrate |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| XAF1 | XIAP associated factor 1 |
| ZNF446 | zinc finger protein 446 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BEX4 | brain expressed, X-linked 4 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CDC37L1 | cell division cycle 37-like 1 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDCA3 | cell division cycle associated 3 |
| CHM | choroideremia (Rab escort protein 1) |
| CLDN4 | claudin 4 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EMP3 | epithelial membrane protein 3 |
| ERF | Ets2 repressor factor |
| FAM53B | family with sequence similarity 53, member B |
| FAT4 | FAT atypical cadherin 4 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FNTB | farnesyltransferase, CAAX box, beta |
| GALK1 | galactokinase 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLOD4 | glyoxalase domain containing 4 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR176 | G protein-coupled receptor 176 |
| GTF2I | general transcription factor IIi |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4E | histone cluster 1, H4e |
| HMOX1 | heme oxygenase 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| KIAA0922 | KIAA0922 |
| KIAA1462 | KIAA1462 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LOC100127972 | uncharacterized LOC100127972 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MMP13 | matrix metallopeptidase 13 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MT2A | metallothionein 2A |
| MYL5 | myosin, light chain 5, regulatory |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDRG4 | NDRG family member 4 |
| NRSN2 | neurensin 2 |
| NUBP2 | nucleotide binding protein 2 |
| OLFML3 | olfactomedin-like 3 |
| OSMR | oncostatin M receptor |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PALMD | palmdelphin |
| PAX9 | paired box 9 |
| PDCD5 | programmed cell death 5 |
| PGD | phosphogluconate dehydrogenase |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLA2G15 | phospholipase A2, group XV |
| PLD3 | phospholipase D family, member 3 |
| PMVK | phosphomevalonate kinase |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RAB5B | RAB5B, member RAS oncogene family |
| RARS | arginyl-tRNA synthetase |
| RPL11 | ribosomal protein L11 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SELT | selenoprotein T |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TH | tyrosine hydroxylase |
| TMEM242 | transmembrane protein 242 |
| TRAPPC2L | trafficking protein particle complex 2-like |
| TRIM16 | tripartite motif containing 16 |
| TRIM25 | tripartite motif containing 25 |
| TWISTNB | TWIST neighbor |
| TXLNG | taxilin gamma |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF227 | zinc finger protein 227 |
| ZNF385D | zinc finger protein 385D |
