diltiazem Gene Set

Dataset	Guide to Pharmacology Chemical Ligands of Receptors
Category	physical interactions
Type	ligand (chemical)
Description	A 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate in which both stereocentres have S configuration. A calcium-channel blocker and vasodilator, it is used as the hydrochloride in the management of angina pectoris and hypertension. (Chemical Entities of Biological Interest Ontology, CHEBI_101278)
External Link	http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2298
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Genes

6 receptors of the diltiazem ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Symbol	Name
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1F	calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit
KCNA1	potassium channel, voltage gated shaker related subfamily A, member 1
KCNA7	potassium channel, voltage gated shaker related subfamily A, member 7
KCNC1	potassium channel, voltage gated Shaw related subfamily C, member 1