dimenhydrinate-2400 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dimenhydrinate-2400 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADD2 adducin 2 (beta)
ADGB androglobin
ADGRD2 adhesion G protein-coupled receptor D2
AGFG1 ArfGAP with FG repeats 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX5 arachidonate 5-lipoxygenase
ANGPTL2 angiopoietin-like 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASGR2 asialoglycoprotein receptor 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C11ORF16 chromosome 11 open reading frame 16
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMKV CaM kinase-like vesicle-associated
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL23 chemokine (C-C motif) ligand 23
CD24 CD24 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDC42 cell division cycle 42
CEP164 centrosomal protein 164kDa
CNOT3 CCR4-NOT transcription complex, subunit 3
CREM cAMP responsive element modulator
CTSF cathepsin F
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
DMWD dystrophia myotonica, WD repeat containing
DNMBP dynamin binding protein
DST dystonin
EFNA3 ephrin-A3
EPS8L3 EPS8-like 3
ETV7 ets variant 7
EXOC6B exocyst complex component 6B
F12 coagulation factor XII (Hageman factor)
FAM49B family with sequence similarity 49, member B
FAS Fas cell surface death receptor
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOXO4 forkhead box O4
FZD6 frizzled class receptor 6
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAB1 GRB2-associated binding protein 1
GCH1 GTP cyclohydrolase 1
GPX2 glutathione peroxidase 2
HDAC7 histone deacetylase 7
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL12RB2 interleukin 12 receptor, beta 2
INPP5K inositol polyphosphate-5-phosphatase K
KCNIP1 Kv channel interacting protein 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM7A lysine (K)-specific demethylase 7A
KHSRP KH-type splicing regulatory protein
KIF1C kinesin family member 1C
LAMA1 laminin, alpha 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MKL2 MKL/myocardin-like 2
NEBL nebulette
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OLFM1 olfactomedin 1
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PAIP2B poly(A) binding protein interacting protein 2B
PARP12 poly (ADP-ribose) polymerase family, member 12
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF7 PHD finger protein 7
PHLDB1 pleckstrin homology-like domain, family B, member 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTCRA pre T-cell antigen receptor alpha
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
SCAMP5 secretory carrier membrane protein 5
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLIT2 slit homolog 2 (Drosophila)
SNX13 sorting nexin 13
SPRR1B small proline-rich protein 1B
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SS18 synovial sarcoma translocation, chromosome 18
STC1 stanniocalcin 1
STRN striatin, calmodulin binding protein
STS steroid sulfatase (microsomal), isozyme S
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBKBP1 TBK1 binding protein 1
TGFBR3 transforming growth factor, beta receptor III
THBS3 thrombospondin 3
TMEM180 transmembrane protein 180
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPTE transmembrane phosphatase with tensin homology
TRIM23 tripartite motif containing 23
TSC22D4 TSC22 domain family, member 4
TUBA8 tubulin, alpha 8
USB1 U6 snRNA biogenesis 1
ZBTB25 zinc finger and BTB domain containing 25
ZNF365 zinc finger protein 365

decreased expression

Symbol Name
ANKFY1 ankyrin repeat and FYVE domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOL6 apolipoprotein L, 6
APOLD1 apolipoprotein L domain containing 1
ATAD5 ATPase family, AAA domain containing 5
BAHD1 bromo adjacent homology domain containing 1
C1ORF95 chromosome 1 open reading frame 95
C4ORF29 chromosome 4 open reading frame 29
CBX4 chromobox homolog 4
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD82 CD82 molecule
CFAP44 cilia and flagella associated protein 44
CHMP6 charged multivesicular body protein 6
CIDEC cell death-inducing DFFA-like effector c
CLCN6 chloride channel, voltage-sensitive 6
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COLEC10 collectin sub-family member 10 (C-type lectin)
CPNE7 copine VII
CPTP ceramide-1-phosphate transfer protein
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CST3 cystatin C
CXCL2 chemokine (C-X-C motif) ligand 2
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
EML4 echinoderm microtubule associated protein like 4
FAM114A1 family with sequence similarity 114, member A1
FAM163A family with sequence similarity 163, member A
FAM184A family with sequence similarity 184, member A
FGL1 fibrinogen-like 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GPHN gephyrin
GPR27 G protein-coupled receptor 27
GRAMD4 GRAM domain containing 4
GSTCD glutathione S-transferase, C-terminal domain containing
GSTZ1 glutathione S-transferase zeta 1
HOPX HOP homeobox
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IP6K1 inositol hexakisphosphate kinase 1
IPO8 importin 8
KLF13 Kruppel-like factor 13
KLK5 kallikrein-related peptidase 5
LAX1 lymphocyte transmembrane adaptor 1
LOC100127972 uncharacterized LOC100127972
LRP2 low density lipoprotein receptor-related protein 2
LRP5 low density lipoprotein receptor-related protein 5
LSP1 lymphocyte-specific protein 1
LTBP2 latent transforming growth factor beta binding protein 2
MEGF8 multiple EGF-like-domains 8
METTL16 methyltransferase like 16
MPDU1 mannose-P-dolichol utilization defect 1
MRPL44 mitochondrial ribosomal protein L44
MTA2 metastasis associated 1 family, member 2
MXD3 MAX dimerization protein 3
NBEAL2 neurobeachin-like 2
NINJ1 ninjurin 1
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NRGN neurogranin (protein kinase C substrate, RC3)
NT5DC3 5'-nucleotidase domain containing 3
NTSR1 neurotensin receptor 1 (high affinity)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PODXL2 podocalyxin-like 2
POR P450 (cytochrome) oxidoreductase
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPT2 palmitoyl-protein thioesterase 2
PRKG2 protein kinase, cGMP-dependent, type II
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RIC8B RIC8 guanine nucleotide exchange factor B
RNF126P1 ring finger protein 126 pseudogene 1
SHARPIN SHANK-associated RH domain interactor
SLC22A14 solute carrier family 22, member 14
SLC22A18 solute carrier family 22, member 18
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPATA2L spermatogenesis associated 2-like
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STK25 serine/threonine kinase 25
TCTN2 tectonic family member 2
TESK1 testis-specific kinase 1
TOR4A torsin family 4, member A
TRAF2 TNF receptor-associated factor 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UGDH UDP-glucose 6-dehydrogenase
WFDC2 WAP four-disulfide core domain 2
XAB2 XPA binding protein 2
ZBED8 zinc finger, BED-type containing 8
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF250 zinc finger protein 250
ZNF428 zinc finger protein 428
ZNF551 zinc finger protein 551
ZNF747 zinc finger protein 747