| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the dimenhydrinate-5450 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIM2 | absent in melanoma 2 |
| ANAPC13 | anaphase promoting complex subunit 13 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CALCR | calcitonin receptor |
| CCDC7 | coiled-coil domain containing 7 |
| CCDC87 | coiled-coil domain containing 87 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD47 | CD47 molecule |
| CD53 | CD53 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDK14 | cyclin-dependent kinase 14 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIB2 | calcium and integrin binding family member 2 |
| CLDN11 | claudin 11 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRMP1 | collapsin response mediator protein 1 |
| DICER1 | dicer 1, ribonuclease type III |
| DMBT1 | deleted in malignant brain tumors 1 |
| EPHB2 | EPH receptor B2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| F12 | coagulation factor XII (Hageman factor) |
| FAM182B | family with sequence similarity 182, member B |
| FAM204A | family with sequence similarity 204, member A |
| FRMD1 | FERM domain containing 1 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GPR22 | G protein-coupled receptor 22 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HDAC7 | histone deacetylase 7 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| INE1 | inactivation escape 1 (non-protein coding) |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0319L | KIAA0319-like |
| KRT15 | keratin 15, type I |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LRRC14 | leucine rich repeat containing 14 |
| MAGEA5 | melanoma antigen family A5 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP4 | microtubule-associated protein 4 |
| MBTD1 | mbt domain containing 1 |
| MEF2D | myocyte enhancer factor 2D |
| MPPE1 | metallophosphoesterase 1 |
| MST1L | macrophage stimulating 1-like |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
| NF1 | neurofibromin 1 |
| NFIB | nuclear factor I/B |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRL | neural retina leucine zipper |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCM1 | pericentriolar material 1 |
| PDE10A | phosphodiesterase 10A |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PEX3 | peroxisomal biogenesis factor 3 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PML | promyelocytic leukemia |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRKCA | protein kinase C, alpha |
| PTN | pleiotrophin |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RASL11B | RAS-like, family 11, member B |
| RORA | RAR-related orphan receptor A |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RRBP1 | ribosome binding protein 1 |
| RS1 | retinoschisin 1 |
| S100A7 | S100 calcium binding protein A7 |
| SDS | serine dehydratase |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STIM1 | stromal interaction molecule 1 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TSC22D4 | TSC22 domain family, member 4 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZDHHC8P1 | zinc finger, DHHC-type containing 8 pseudogene 1 |
| ZNF3 | zinc finger protein 3 |
| ZNF516 | zinc finger protein 516 |
| ZNF589 | zinc finger protein 589 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACTL8 | actin-like 8 |
| ADCK4 | aarF domain containing kinase 4 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALPK1 | alpha-kinase 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARMC4 | armadillo repeat containing 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BST2 | bone marrow stromal cell antigen 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAPN5 | calpain 5 |
| CBX8 | chromobox homolog 8 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLSPN | claspin |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CST6 | cystatin E/M |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EFNA3 | ephrin-A3 |
| FAM212B | family with sequence similarity 212, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FOSL1 | FOS-like antigen 1 |
| FOXN2 | forkhead box N2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GLCE | glucuronic acid epimerase |
| GPR143 | G protein-coupled receptor 143 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4D | histone cluster 1, H4d |
| HOXC5 | homeobox C5 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IQCG | IQ motif containing G |
| IRF1 | interferon regulatory factor 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA0754 | KIAA0754 |
| KLF2 | Kruppel-like factor 2 |
| KLHL25 | kelch-like family member 25 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCDHB13 | protocadherin beta 13 |
| PDE8B | phosphodiesterase 8B |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PITX2 | paired-like homeodomain 2 |
| PLCG1 | phospholipase C, gamma 1 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RLN1 | relaxin 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RWDD3 | RWD domain containing 3 |
| SAMHD1 | SAM domain and HD domain 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDC3 | syndecan 3 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SH2D4A | SH2 domain containing 4A |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STEAP4 | STEAP family member 4 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM19 | transmembrane protein 19 |
| TMEM209 | transmembrane protein 209 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TSGA10 | testis specific, 10 |
| VEGFC | vascular endothelial growth factor C |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF254 | zinc finger protein 254 |
| ZNF446 | zinc finger protein 446 |
| ZNF701 | zinc finger protein 701 |
| ZNF85 | zinc finger protein 85 |
