dimenhydrinate-6352 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the dimenhydrinate-6352 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADORA1 adenosine A1 receptor
AIM2 absent in melanoma 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANKLE2 ankyrin repeat and LEM domain containing 2
APOLD1 apolipoprotein L domain containing 1
ART1 ADP-ribosyltransferase 1
ATAT1 alpha tubulin acetyltransferase 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BOLA1 bolA family member 1
BTD biotinidase
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C17ORF70 chromosome 17 open reading frame 70
C21ORF2 chromosome 21 open reading frame 2
C22ORF24 chromosome 22 open reading frame 24
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD34 CD34 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CNOT4 CCR4-NOT transcription complex, subunit 4
CRTC1 CREB regulated transcription coactivator 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYLD cylindromatosis (turban tumor syndrome)
DCAKD dephospho-CoA kinase domain containing
DHRS12 dehydrogenase/reductase (SDR family) member 12
E2F4 E2F transcription factor 4, p107/p130-binding
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EMP1 epithelial membrane protein 1
ERC2-IT1 ERC2 intronic transcript 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
HIST1H1D histone cluster 1, H1d
HOXC10 homeobox C10
HSDL2 hydroxysteroid dehydrogenase like 2
IFT122 intraflagellar transport 122
IL11 interleukin 11
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KPNA6 karyopherin alpha 6 (importin alpha 7)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMC2 laminin, gamma 2
LRRN3 leucine rich repeat neuronal 3
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP2K7 mitogen-activated protein kinase kinase 7
METTL16 methyltransferase like 16
MKL1 megakaryoblastic leukemia (translocation) 1
MSL3 male-specific lethal 3 homolog (Drosophila)
MXD4 MAX dimerization protein 4
NEB nebulin
NF2 neurofibromin 2 (merlin)
NOP16 NOP16 nucleolar protein
NRP2 neuropilin 2
NUMA1 nuclear mitotic apparatus protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PHF20 PHD finger protein 20
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAA phospholipase A2-activating protein
PLCG1 phospholipase C, gamma 1
PLD1 phospholipase D1, phosphatidylcholine-specific
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POM121 POM121 transmembrane nucleoporin
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTN pleiotrophin
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB3B RAB3B, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RIN3 Ras and Rab interactor 3
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERHL2 serine hydrolase-like 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIDT2 SID1 transmembrane family, member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SZRD1 SUZ RNA binding domain containing 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TEF thyrotrophic embryonic factor
TGFB2 transforming growth factor, beta 2
TNN tenascin N
UBE4B ubiquitination factor E4B
UBQLN4 ubiquilin 4
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VARS valyl-tRNA synthetase
VAV3 vav 3 guanine nucleotide exchange factor
VIPR2 vasoactive intestinal peptide receptor 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YOD1 YOD1 deubiquitinase
ZER1 zyg-11 related, cell cycle regulator

decreased expression

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMCX2 armadillo repeat containing, X-linked 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
C1R complement component 1, r subcomponent
C8ORF60 chromosome 8 open reading frame 60
CCDC69 coiled-coil domain containing 69
CDH3 cadherin 3, type 1, P-cadherin (placental)
CLEC2B C-type lectin domain family 2, member B
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRELD1 cysteine-rich with EGF-like domains 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCAF4 DDB1 and CUL4 associated factor 4
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
EFTUD1 elongation factor Tu GTP binding domain containing 1
EGF epidermal growth factor
EN2 engrailed homeobox 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FA2H fatty acid 2-hydroxylase
FAM186A family with sequence similarity 186, member A
FBXL6 F-box and leucine-rich repeat protein 6
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FOXA1 forkhead box A1
GPR39 G protein-coupled receptor 39
HIST1H2AJ histone cluster 1, H2aj
HOMER2 homer scaffolding protein 2
HOXB9 homeobox B9
HOXC4 homeobox C4
HOXC8 homeobox C8
HYI hydroxypyruvate isomerase (putative)
IL11RA interleukin 11 receptor, alpha
ITGA10 integrin, alpha 10
KDM4D lysine (K)-specific demethylase 4D
KDM5C lysine (K)-specific demethylase 5C
LAMA5 laminin, alpha 5
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC8E leucine rich repeat containing 8 family, member E
LYPD1 LY6/PLAUR domain containing 1
MAPK12 mitogen-activated protein kinase 12
MBIP MAP3K12 binding inhibitory protein 1
MBTD1 mbt domain containing 1
MYOZ3 myozenin 3
NBAS neuroblastoma amplified sequence
NDRG4 NDRG family member 4
NR1H3 nuclear receptor subfamily 1, group H, member 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PC pyruvate carboxylase
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE12 phosphodiesterase 12
PEX26 peroxisomal biogenesis factor 26
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
POMT2 protein-O-mannosyltransferase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF31 ring finger protein 31
RUSC2 RUN and SH3 domain containing 2
SCPEP1 serine carboxypeptidase 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHROOM2 shroom family member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC46A3 solute carrier family 46, member 3
SLITRK5 SLIT and NTRK-like family, member 5
STX1A syntaxin 1A (brain)
SYTL2 synaptotagmin-like 2
THOC6 THO complex 6
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TM7SF2 transmembrane 7 superfamily member 2
TMEM121 transmembrane protein 121
TMEM209 transmembrane protein 209
TMEM8B transmembrane protein 8B
TPCN1 two pore segment channel 1
TRIM58 tripartite motif containing 58
TRIM66 tripartite motif containing 66
UBTD1 ubiquitin domain containing 1
WDR46 WD repeat domain 46
YIPF1 Yip1 domain family, member 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZMAT5 zinc finger, matrin-type 5
ZNF350 zinc finger protein 350
ZNF408 zinc finger protein 408
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZNF768 zinc finger protein 768
ZNF862 zinc finger protein 862
ZXDC ZXD family zinc finger C