dimeric iga immunoglobulin complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. (Gene Ontology, GO_0071750)
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3 proteins localized to the dimeric iga immunoglobulin complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) 0.237908
IGHA1 immunoglobulin heavy constant alpha 1 0.237908
JCHAIN joining chain of multimeric IgA and IgM 0.237908