| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the dinoprost-2446 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ADGRG3 | adhesion G protein-coupled receptor G3 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| AREG | amphiregulin |
| ARL4C | ADP-ribosylation factor-like 4C |
| AVPI1 | arginine vasopressin-induced 1 |
| AXL | AXL receptor tyrosine kinase |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CAT | catalase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD38 | CD38 molecule |
| CD86 | CD86 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHN2 | chimerin 2 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| COL4A2 | collagen, type IV, alpha 2 |
| CREM | cAMP responsive element modulator |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK4 | dedicator of cytokinesis 4 |
| DUSP4 | dual specificity phosphatase 4 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EML2 | echinoderm microtubule associated protein like 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| FADS3 | fatty acid desaturase 3 |
| FAM131A | family with sequence similarity 131, member A |
| FBLN1 | fibulin 1 |
| FBXO31 | F-box protein 31 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FPR1 | formyl peptide receptor 1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GALC | galactosylceramidase |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPR182 | G protein-coupled receptor 182 |
| GPR183 | G protein-coupled receptor 183 |
| GPR65 | G protein-coupled receptor 65 |
| GRAMD1B | GRAM domain containing 1B |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HMGB3 | high mobility group box 3 |
| HOXA1 | homeobox A1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL10RA | interleukin 10 receptor, alpha |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KYNU | kynureninase |
| LIF | leukemia inhibitory factor |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| MCAM | melanoma cell adhesion molecule |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MX2 | MX dynamin-like GTPase 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| OSM | oncostatin M |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLK3 | polo-like kinase 3 |
| PLSCR1 | phospholipid scramblase 1 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
| RASAL2 | RAS protein activator like 2 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| SAFB | scaffold attachment factor B |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDC2 | syndecan 2 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH2D2A | SH2 domain containing 2A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBC1D2 | TBC1 domain family, member 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THBS1 | thrombospondin 1 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| TRPS1 | trichorhinophalangeal syndrome I |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| AGBL5 | ATP/GTP binding protein-like 5 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMC6 | armadillo repeat containing 6 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BSPRY | B-box and SPRY domain containing |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA2 | carbonic anhydrase II |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC86 | coiled-coil domain containing 86 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| COQ6 | coenzyme Q6 monooxygenase |
| DDN | dendrin |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEAF1 | DEAF1 transcription factor |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DSPP | dentin sialophosphoprotein |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EMID1 | EMI domain containing 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ENAH | enabled homolog (Drosophila) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM127B | family with sequence similarity 127, member B |
| FAM204A | family with sequence similarity 204, member A |
| FAM208B | family with sequence similarity 208, member B |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FLT4 | fms-related tyrosine kinase 4 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GALK1 | galactokinase 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR27 | G protein-coupled receptor 27 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2AI | histone cluster 1, H2ai |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| IL2 | interleukin 2 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| KLHL21 | kelch-like family member 21 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC257152 | uncharacterized LOC257152 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MYBPH | myosin binding protein H |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NEUROD4 | neuronal differentiation 4 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OLFML2A | olfactomedin-like 2A |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PDE12 | phosphodiesterase 12 |
| PDGFD | platelet derived growth factor D |
| PDGFRL | platelet-derived growth factor receptor-like |
| PEX26 | peroxisomal biogenesis factor 26 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PRDM13 | PR domain containing 13 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RCAN3 | RCAN family member 3 |
| RECQL4 | RecQ protein-like 4 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SETD1A | SET domain containing 1A |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| SURF2 | surfeit 2 |
| SV2A | synaptic vesicle glycoprotein 2A |
| TAGLN | transgelin |
| THEM6 | thioesterase superfamily member 6 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) |
| TMEM104 | transmembrane protein 104 |
| TMEM254 | transmembrane protein 254 |
| TMEM53 | transmembrane protein 53 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TSC22D4 | TSC22 domain family, member 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUFT1 | tuftelin 1 |
| UPK3A | uroplakin 3A |
| VEGFC | vascular endothelial growth factor C |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| WDR62 | WD repeat domain 62 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF134 | zinc finger protein 134 |
| ZNF428 | zinc finger protein 428 |
| ZNF493 | zinc finger protein 493 |
