dinoprost-3308 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the dinoprost-3308 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
AIRE autoimmune regulator
ALOX5 arachidonate 5-lipoxygenase
ANKH ANKH inorganic pyrophosphate transport regulator
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARL4D ADP-ribosylation factor-like 4D
ARTN artemin
ATM ATM serine/threonine kinase
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCORL1 BCL6 corepressor-like 1
C17ORF53 chromosome 17 open reading frame 53
C9ORF40 chromosome 9 open reading frame 40
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC134 coiled-coil domain containing 134
CD8A CD8a molecule
CDK14 cyclin-dependent kinase 14
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CFLAR CASP8 and FADD-like apoptosis regulator
COL17A1 collagen, type XVII, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CTNS cystinosin, lysosomal cystine transporter
DCN decorin
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMXL2 Dmx-like 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP9 dual specificity phosphatase 9
ERP44 endoplasmic reticulum protein 44
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXG1 forkhead box G1
FSHB follicle stimulating hormone, beta polypeptide
GCKR glucokinase (hexokinase 4) regulator
GFOD2 glucose-fructose oxidoreductase domain containing 2
GJC2 gap junction protein, gamma 2, 47kDa
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPC1 glypican 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HFE hemochromatosis
HIPK2 homeodomain interacting protein kinase 2
HIST1H1D histone cluster 1, H1d
HIST1H4C histone cluster 1, H4c
HLF hepatic leukemia factor
HP1BP3 heterochromatin protein 1, binding protein 3
IL22 interleukin 22
IL6ST interleukin 6 signal transducer
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM5A lysine (K)-specific demethylase 5A
KIAA0319L KIAA0319-like
KRT16 keratin 16, type I
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAX MYC associated factor X
MFGE8 milk fat globule-EGF factor 8 protein
MMP11 matrix metallopeptidase 11
N4BP3 NEDD4 binding protein 3
NF2 neurofibromin 2 (merlin)
NUP188 nucleoporin 188kDa
OSMR oncostatin M receptor
PCSK6 proprotein convertase subtilisin/kexin type 6
PHF1 PHD finger protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
POLL polymerase (DNA directed), lambda
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRDM10 PR domain containing 10
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RASA3 RAS p21 protein activator 3
RBL2 retinoblastoma-like 2
RFPL3 ret finger protein-like 3
RHOH ras homolog family member H
RIMS2 regulating synaptic membrane exocytosis 2
RIMS3 regulating synaptic membrane exocytosis 3
RNFT1 ring finger protein, transmembrane 1
RPAIN RPA interacting protein
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RSU1 Ras suppressor protein 1
RUNX1 runt-related transcription factor 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SGCE sarcoglycan, epsilon
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX13 sorting nexin 13
SPATA5L1 spermatogenesis associated 5-like 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D29 TBC1 domain family, member 29
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TSPAN9 tetraspanin 9
VASH2 vasohibin 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
AHNAK2 AHNAK nucleoprotein 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARMC4 armadillo repeat containing 4
ARRB2 arrestin, beta 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C11ORF30 chromosome 11 open reading frame 30
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF54 chromosome 2 open reading frame 54
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD3EAP CD3e molecule, epsilon associated protein
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CLGN calmegin
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGKD diacylglycerol kinase, delta 130kDa
DPY19L1P1 DPY19L1 pseudogene 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPHA2 EPH receptor A2
ERCC5 excision repair cross-complementation group 5
EXD3 exonuclease 3'-5' domain containing 3
FAM169A family with sequence similarity 169, member A
FBRS fibrosin
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ22184
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR87 G protein-coupled receptor 87
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HYI hydroxypyruvate isomerase (putative)
IMPACT impact RWD domain protein
IQSEC2 IQ motif and Sec7 domain 2
IRF9 interferon regulatory factor 9
ITPKC inositol-trisphosphate 3-kinase C
KLF7 Kruppel-like factor 7 (ubiquitous)
LONP2 lon peptidase 2, peroxisomal
LRP5L low density lipoprotein receptor-related protein 5-like
LTC4S leukotriene C4 synthase
MAP9 microtubule-associated protein 9
MAST3 microtubule associated serine/threonine kinase 3
MICALL2 MICAL-like 2
MRPL44 mitochondrial ribosomal protein L44
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
MYBBP1A MYB binding protein (P160) 1a
NES nestin
NXPH4 neurexophilin 4
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PC pyruvate carboxylase
PCBP4 poly(rC) binding protein 4
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RIN2 Ras and Rab interactor 2
RNF43 ring finger protein 43
RPAP1 RNA polymerase II associated protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
SECTM1 secreted and transmembrane 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIDT1 SID1 transmembrane family, member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SREK1IP1 SREK1-interacting protein 1
STAB2 stabilin 2
STRA6 stimulated by retinoic acid 6
SUN2 Sad1 and UNC84 domain containing 2
SYT17 synaptotagmin XVII
TAOK1 TAO kinase 1
TBX19 T-box 19
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM53 transmembrane protein 53
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN5 tetraspanin 5
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
WDR91 WD repeat domain 91
ZBED1 zinc finger, BED-type containing 1
ZIC3 Zic family member 3
ZNF134 zinc finger protein 134
ZNF137P zinc finger protein 137, pseudogene
ZNF532 zinc finger protein 532