dinoprost-6308 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dinoprost-6308 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACTA1 actin, alpha 1, skeletal muscle
AIM2 absent in melanoma 2
ALAD aminolevulinate dehydratase
ALDOB aldolase B, fructose-bisphosphate
APOA4 apolipoprotein A-IV
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH7 cadherin 7, type 2
CDV3 CDV3 homolog (mouse)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC4A C-type lectin domain family 4, member A
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
CYB561 cytochrome b561
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DENND2A DENN/MADD domain containing 2A
DMTN dematin actin binding protein
DZIP1 DAZ interacting zinc finger protein 1
EHF ets homologous factor
EPHB2 EPH receptor B2
FLJ11292
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
GIMAP6 GTPase, IMAP family member 6
GK glycerol kinase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPC3 glypican 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTDC1 glycosyltransferase-like domain containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HOMER3 homer scaffolding protein 3
IGSF6 immunoglobulin superfamily, member 6
IL11 interleukin 11
KANK1 KN motif and ankyrin repeat domains 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD14 potassium channel tetramerization domain containing 14
KIAA0368 KIAA0368
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KPNA5 karyopherin alpha 5 (importin alpha 6)
LMBR1L limb development membrane protein 1-like
MAP7 microtubule-associated protein 7
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MATN1 matrilin 1, cartilage matrix protein
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFGE8 milk fat globule-EGF factor 8 protein
MYOZ3 myozenin 3
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NOVA2 neuro-oncological ventral antigen 2
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDH9 protocadherin 9
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PRB3 proline-rich protein BstNI subfamily 3
PRSS16 protease, serine, 16 (thymus)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RANBP3 RAN binding protein 3
REEP1 receptor accessory protein 1
RGCC regulator of cell cycle
RGS12 regulator of G-protein signaling 12
SAMD9 sterile alpha motif domain containing 9
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STC1 stanniocalcin 1
STK16 serine/threonine kinase 16
TGFB2 transforming growth factor, beta 2
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TUBGCP2 tubulin, gamma complex associated protein 2
USP19 ubiquitin specific peptidase 19
VAC14 Vac14 homolog (S. cerevisiae)
VCAN versican
VWA5A von Willebrand factor A domain containing 5A
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZNF222 zinc finger protein 222
ZNF37BP zinc finger protein 37B, pseudogene
ZNF44 zinc finger protein 44
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARHGAP24 Rho GTPase activating protein 24
ATAD5 ATPase family, AAA domain containing 5
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BGLAP bone gamma-carboxyglutamate (gla) protein
C17ORF70 chromosome 17 open reading frame 70
C6ORF47 chromosome 6 open reading frame 47
CALCOCO1 calcium binding and coiled-coil domain 1
CBX4 chromobox homolog 4
CCDC85C coiled-coil domain containing 85C
CCNJ cyclin J
CEP131 centrosomal protein 131kDa
CGREF1 cell growth regulator with EF-hand domain 1
CISH cytokine inducible SH2-containing protein
CLDN15 claudin 15
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COG7 component of oligomeric golgi complex 7
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ELOVL4 ELOVL fatty acid elongase 4
ERCC2 excision repair cross-complementation group 2
EVPL envoplakin
FAM173A family with sequence similarity 173, member A
FAM50B family with sequence similarity 50, member B
FAT4 FAT atypical cadherin 4
FEM1C fem-1 homolog c (C. elegans)
FKBPL FK506 binding protein like
FSD1 fibronectin type III and SPRY domain containing 1
GALT galactose-1-phosphate uridylyltransferase
GAMT guanidinoacetate N-methyltransferase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCHFR GTP cyclohydrolase I feedback regulator
GDAP1 ganglioside induced differentiation associated protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH2L G patch domain containing 2-like
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPS2 G protein pathway suppressor 2
GUSBP3 glucuronidase, beta pseudogene 3
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IRF1 interferon regulatory factor 1
KLF11 Kruppel-like factor 11
LY6G5C lymphocyte antigen 6 complex, locus G5C
MED15 mediator complex subunit 15
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMP1 matrix metallopeptidase 1
MN1 meningioma (disrupted in balanced translocation) 1
MUC7 mucin 7, secreted
NABP2 nucleic acid binding protein 2
NDP Norrie disease (pseudoglioma)
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
PALMD palmdelphin
PC pyruvate carboxylase
PCOLCE procollagen C-endopeptidase enhancer
PEX26 peroxisomal biogenesis factor 26
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCD1 phospholipase C, delta 1
PRPH peripherin
PRR3 proline rich 3
PSKH1 protein serine kinase H1
RNF121 ring finger protein 121
RNF44 ring finger protein 44
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SALL2 spalt-like transcription factor 2
SETBP1 SET binding protein 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SMAD7 SMAD family member 7
SNIP1 Smad nuclear interacting protein 1
SNORA21 small nucleolar RNA, H/ACA box 21
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNPO synaptopodin
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TENM4 teneurin transmembrane protein 4
TM7SF3 transmembrane 7 superfamily member 3
TMEM120B transmembrane protein 120B
TMEM2 transmembrane protein 2
TMEM242 transmembrane protein 242
TRAPPC11 trafficking protein particle complex 11
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC23 tetratricopeptide repeat domain 23
URM1 ubiquitin related modifier 1
USB1 U6 snRNA biogenesis 1
WDR18 WD repeat domain 18
WDR46 WD repeat domain 46
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF358 zinc finger protein 358
ZNF696 zinc finger protein 696
ZNF787 zinc finger protein 787
ZNF862 zinc finger protein 862