| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the dinoprostone-6547 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALS2CL | ALS2 C-terminal like |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANGPTL4 | angiopoietin-like 4 |
| ANXA10 | annexin A10 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATM | ATM serine/threonine kinase |
| BAX | BCL2-associated X protein |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCNO | cyclin O |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42 | cell division cycle 42 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHD4 | chromodomain helicase DNA binding protein 4 |
| CLSPN | claspin |
| CRYL1 | crystallin, lambda 1 |
| CSNK1E | casein kinase 1, epsilon |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CTH | cystathionine gamma-lyase |
| CTSZ | cathepsin Z |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDIT4 | DNA-damage-inducible transcript 4 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| EPAS1 | endothelial PAS domain protein 1 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HBEGF | heparin-binding EGF-like growth factor |
| HIRA | histone cell cycle regulator |
| HMOX1 | heme oxygenase 1 |
| IFI44L | interferon-induced protein 44-like |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL33 | interleukin 33 |
| IL33R | interleukin 33 receptor |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA1644 | KIAA1644 |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LAMA4 | laminin, alpha 4 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAP7 | microtubule-associated protein 7 |
| MAX | MYC associated factor X |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MINK1 | misshapen-like kinase 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYRF | myelin regulatory factor |
| NPR3 | natriuretic peptide receptor 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 |
| PKP1 | plakophilin 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTGES | prostaglandin E synthase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTHLH | parathyroid hormone-like hormone |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| QKI | QKI, KH domain containing, RNA binding |
| RAB4B | RAB4B, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RGS14 | regulator of G-protein signaling 14 |
| RHOT2 | ras homolog family member T2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RXRA | retinoid X receptor, alpha |
| S100P | S100 calcium binding protein P |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| STC1 | stanniocalcin 1 |
| TADA2A | transcriptional adaptor 2A |
| TFF1 | trefoil factor 1 |
| TSPAN9 | tetraspanin 9 |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| WWC1 | WW and C2 domain containing 1 |
| YIPF2 | Yip1 domain family, member 2 |
| ZNF318 | zinc finger protein 318 |
| ZNF473 | zinc finger protein 473 |
| Symbol | Name |
|---|---|
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| BMP15 | bone morphogenetic protein 15 |
| CCNJL | cyclin J-like |
| CD70 | CD70 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CFAP44 | cilia and flagella associated protein 44 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CPA4 | carboxypeptidase A4 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTGF | connective tissue growth factor |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| EDN1 | endothelin 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FBRS | fibrosin |
| FGF13 | fibroblast growth factor 13 |
| FOXD1 | forkhead box D1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR3 | G protein-coupled receptor 3 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HHAT | hedgehog acyltransferase |
| HIST2H2BE | histone cluster 2, H2be |
| IREB2 | iron-responsive element binding protein 2 |
| KIAA1462 | KIAA1462 |
| KLHDC4 | kelch domain containing 4 |
| KLK7 | kallikrein-related peptidase 7 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEA5 | melanoma antigen family A5 |
| MAGEF1 | melanoma antigen family F1 |
| MAMLD1 | mastermind-like domain containing 1 |
| MCRS1 | microspherule protein 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP1 | matrix metallopeptidase 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRTN | neurturin |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ONECUT2 | one cut homeobox 2 |
| OSMR | oncostatin M receptor |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| PADI2 | peptidyl arginine deiminase, type II |
| PALM | paralemmin |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRKCE | protein kinase C, epsilon |
| PRR16 | proline rich 16 |
| PTX3 | pentraxin 3, long |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAI2 | retinoic acid induced 2 |
| RGS20 | regulator of G-protein signaling 20 |
| RNF39 | ring finger protein 39 |
| RUNDC3B | RUN domain containing 3B |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SPIDR | scaffolding protein involved in DNA repair |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SYCP2 | synaptonemal complex protein 2 |
| TAOK1 | TAO kinase 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM21 | tripartite motif containing 21 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFB | vascular endothelial growth factor B |
| VGF | VGF nerve growth factor inducible |
| WDR25 | WD repeat domain 25 |
| ZNF219 | zinc finger protein 219 |
| ZNF254 | zinc finger protein 254 |
| ZNF552 | zinc finger protein 552 |
| ZNF675 | zinc finger protein 675 |
