| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dinoprostone-6552 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
| AR | androgen receptor |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATF6 | activating transcription factor 6 |
| AURKA | aurora kinase A |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CDK10 | cyclin-dependent kinase 10 |
| CGA | glycoprotein hormones, alpha polypeptide |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CSNK1A1 | casein kinase 1, alpha 1 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DMTN | dematin actin binding protein |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DSCR3 | Down syndrome critical region 3 |
| EAF2 | ELL associated factor 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNA3 | ephrin-A3 |
| FAM188A | family with sequence similarity 188, member A |
| FEM1C | fem-1 homolog c (C. elegans) |
| FERMT1 | fermitin family member 1 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FGF23 | fibroblast growth factor 23 |
| FH | fumarate hydratase |
| FLJ11292 | |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GCAT | glycine C-acetyltransferase |
| GPR1 | G protein-coupled receptor 1 |
| HIST1H2AL | histone cluster 1, H2al |
| HMGXB3 | HMG box domain containing 3 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL1R1 | interleukin 1 receptor, type I |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQCE | IQ motif containing E |
| KAZN | kazrin, periplakin interacting protein |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LYST | lysosomal trafficking regulator |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MAP4 | microtubule-associated protein 4 |
| MAX | MYC associated factor X |
| MED6 | mediator complex subunit 6 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MINK1 | misshapen-like kinase 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO1E | myosin IE |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLXNB1 | plexin B1 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRKCE | protein kinase C, epsilon |
| PRPF4B | pre-mRNA processing factor 4B |
| PSEN1 | presenilin 1 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAB23 | RAB23, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RBKS | ribokinase |
| RBL1 | retinoblastoma-like 1 |
| REST | RE1-silencing transcription factor |
| RHOQ | ras homolog family member Q |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| RPL7 | ribosomal protein L7 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIRPA | signal-regulatory protein alpha |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFF2 | trefoil factor 2 |
| TMSB15A | thymosin beta 15a |
| TNS2 | tensin 2 |
| TROVE2 | TROVE domain family, member 2 |
| TTBK2 | tau tubulin kinase 2 |
| UBQLN4 | ubiquilin 4 |
| UFSP2 | UFM1-specific peptidase 2 |
| VASP | vasodilator-stimulated phosphoprotein |
| ZBTB1 | zinc finger and BTB domain containing 1 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATF7 | activating transcription factor 7 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA10 | carbonic anhydrase X |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CD1A | CD1a molecule |
| CES1 | carboxylesterase 1 |
| CLSTN2 | calsyntenin 2 |
| CUX2 | cut-like homeobox 2 |
| DAGLA | diacylglycerol lipase, alpha |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEPDC5 | DEP domain containing 5 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GPATCH3 | G patch domain containing 3 |
| GPR157 | G protein-coupled receptor 157 |
| GPR19 | G protein-coupled receptor 19 |
| GPR20 | G protein-coupled receptor 20 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BJ | histone cluster 1, H2bj |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| IFI27 | interferon, alpha-inducible protein 27 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| JMJD4 | jumonji domain containing 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LHX1 | LIM homeobox 1 |
| LINS | lines homolog (Drosophila) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MFAP2 | microfibrillar-associated protein 2 |
| MXD3 | MAX dimerization protein 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NXF2 | nuclear RNA export factor 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PDE8B | phosphodiesterase 8B |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNB3 | plexin B3 |
| PMCH | pro-melanin-concentrating hormone |
| POLM | polymerase (DNA directed), mu |
| POU2F1 | POU class 2 homeobox 1 |
| PRAMEF12 | PRAME family member 12 |
| PRM1 | protamine 1 |
| PTK6 | protein tyrosine kinase 6 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RANGRF | RAN guanine nucleotide release factor |
| RGS9 | regulator of G-protein signaling 9 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF2 | ring finger protein 2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A7 | S100 calcium binding protein A7 |
| SALL2 | spalt-like transcription factor 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| STX1A | syntaxin 1A (brain) |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TDRD1 | tudor domain containing 1 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM36 | tripartite motif containing 36 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN1 | tetraspanin 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
