| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the dinoprostone-6590 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADCY7 | adenylate cyclase 7 |
| ALPK1 | alpha-kinase 1 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATF6B | activating transcription factor 6 beta |
| BAIAP2 | BAI1-associated protein 2 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCNO | cyclin O |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNN1 | calponin 1, basic, smooth muscle |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DTNA | dystrobrevin, alpha |
| DUSP1 | dual specificity phosphatase 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EGFR | epidermal growth factor receptor |
| EIF1 | eukaryotic translation initiation factor 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPR153 | G protein-coupled receptor 153 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GYG2 | glycogenin 2 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HLA-F | major histocompatibility complex, class I, F |
| HOXC8 | homeobox C8 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL27RA | interleukin 27 receptor, alpha |
| IL4R | interleukin 4 receptor |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KAT5 | K(lysine) acetyltransferase 5 |
| LAT2 | linker for activation of T cells family, member 2 |
| LHX6 | LIM homeobox 6 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC644450 | uncharacterized LOC644450 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LUZP1 | leucine zipper protein 1 |
| MADD | MAP-kinase activating death domain |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP1B | microtubule-associated protein 1B |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 |
| MBTD1 | mbt domain containing 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIIP | migration and invasion inhibitory protein |
| MTRF1L | mitochondrial translational release factor 1-like |
| NEK11 | NIMA-related kinase 11 |
| NOL10 | nucleolar protein 10 |
| NOL12 | nucleolar protein 12 |
| NOP16 | NOP16 nucleolar protein |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PAPPA2 | pappalysin 2 |
| PCM1 | pericentriolar material 1 |
| PRMT7 | protein arginine methyltransferase 7 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RBM42 | RNA binding motif protein 42 |
| REC8 | REC8 meiotic recombination protein |
| RIN1 | Ras and Rab interactor 1 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RWDD3 | RWD domain containing 3 |
| SAFB | scaffold attachment factor B |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCAF4 | SR-related CTD-associated factor 4 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPAG4 | sperm associated antigen 4 |
| ST20 | suppressor of tumorigenicity 20 |
| STK38L | serine/threonine kinase 38 like |
| SYNGR1 | synaptogyrin 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TPM1 | tropomyosin 1 (alpha) |
| TRIM14 | tripartite motif containing 14 |
| TRIM25 | tripartite motif containing 25 |
| TRMT61A | tRNA methyltransferase 61A |
| UBOX5 | U-box domain containing 5 |
| UBXN1 | UBX domain protein 1 |
| VEGFB | vascular endothelial growth factor B |
| WBP4 | WW domain binding protein 4 |
| XAB2 | XPA binding protein 2 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF174 | zinc finger protein 174 |
| ZNF552 | zinc finger protein 552 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADM | adrenomedullin |
| AES | amino-terminal enhancer of split |
| APOLD1 | apolipoprotein L domain containing 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CD82 | CD82 molecule |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLDND1 | claudin domain containing 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDA1 | DET1 and DDB1 associated 1 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EFNA3 | ephrin-A3 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERF | Ets2 repressor factor |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FNDC3B | fibronectin type III domain containing 3B |
| GAB2 | GRB2-associated binding protein 2 |
| GALK1 | galactokinase 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GRPR | gastrin-releasing peptide receptor |
| GTPBP2 | GTP binding protein 2 |
| HHAT | hedgehog acyltransferase |
| HIST1H2AI | histone cluster 1, H2ai |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIAA0125 | KIAA0125 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NRSN2 | neurensin 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PER1 | period circadian clock 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLAC1 | placenta-specific 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLL | polymerase (DNA directed), lambda |
| POMT2 | protein-O-mannosyltransferase 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAB23 | RAB23, member RAS oncogene family |
| RAB5C | RAB5C, member RAS oncogene family |
| RNF146 | ring finger protein 146 |
| SAMHD1 | SAM domain and HD domain 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STIM1 | stromal interaction molecule 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TEP1 | telomerase-associated protein 1 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THBS3 | thrombospondin 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM230 | transmembrane protein 230 |
| TMEM57 | transmembrane protein 57 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN1 | tetraspanin 1 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| UNC119 | unc-119 homolog (C. elegans) |
| USP36 | ubiquitin specific peptidase 36 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VGF | VGF nerve growth factor inducible |
| WDR4 | WD repeat domain 4 |
| WDR76 | WD repeat domain 76 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF254 | zinc finger protein 254 |
| ZNF324 | zinc finger protein 324 |
| ZNF34 | zinc finger protein 34 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF573 | zinc finger protein 573 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |