dioxybenzone-3101 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dioxybenzone-3101 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AGFG2 ArfGAP with FG repeats 2
AKAP4 A kinase (PRKA) anchor protein 4
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APOC4 apolipoprotein C-IV
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATG10 autophagy related 10
BMP15 bone morphogenetic protein 15
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALCR calcitonin receptor
CBR3 carbonyl reductase 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CNTD2 cyclin N-terminal domain containing 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CXXC4 CXXC finger protein 4
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DLX4 distal-less homeobox 4
DNAH17 dynein, axonemal, heavy chain 17
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP1 dual specificity phosphatase 1
EPYC epiphycan
FAM120C family with sequence similarity 120C
FBXO22 F-box protein 22
FGF4 fibroblast growth factor 4
GEMIN7 gem (nuclear organelle) associated protein 7
GLI2 GLI family zinc finger 2
GMPR guanosine monophosphate reductase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPR15 G protein-coupled receptor 15
GRIK2 glutamate receptor, ionotropic, kainate 2
GRTP1 growth hormone regulated TBC protein 1
GVINP1 GTPase, very large interferon inducible pseudogene 1
HDAC6 histone deacetylase 6
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H4F histone cluster 1, H4f
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPG2 heparan sulfate proteoglycan 2
ICAM1 intercellular adhesion molecule 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL21R interleukin 21 receptor
ITGB4 integrin, beta 4
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KIAA0040 KIAA0040
KIAA0513 KIAA0513
KIF1C kinesin family member 1C
KIF3A kinesin family member 3A
KRT81 keratin 81, type II
LTBP1 latent transforming growth factor beta binding protein 1
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MYL10 myosin, light chain 10, regulatory
NAV2 neuron navigator 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NQO1 NAD(P)H dehydrogenase, quinone 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OSBPL10 oxysterol binding protein-like 10
PLIN2 perilipin 2
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRPH2 peripherin 2 (retinal degeneration, slow)
PRSS8 protease, serine, 8
PSG9 pregnancy specific beta-1-glycoprotein 9
PTPRM protein tyrosine phosphatase, receptor type, M
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RASAL2 RAS protein activator like 2
RELN reelin
ROM1 retinal outer segment membrane protein 1
RPL35A ribosomal protein L35a
RRBP1 ribosome binding protein 1
RTEL1 regulator of telomere elongation helicase 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEZ6L seizure related 6 homolog (mouse)-like
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLN sarcolipin
SOD2 superoxide dismutase 2, mitochondrial
SORBS3 sorbin and SH3 domain containing 3
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPDEF SAM pointed domain containing ETS transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCTN2 tectonic family member 2
TDRD1 tudor domain containing 1
TFF2 trefoil factor 2
TRD T cell receptor delta locus
TRIM31 tripartite motif containing 31
TRIM45 tripartite motif containing 45
TSPAN9 tetraspanin 9
TYMP thymidine phosphorylase
USP22 ubiquitin specific peptidase 22
UTS2 urotensin 2
ZFPL1 zinc finger protein-like 1
ZNF219 zinc finger protein 219
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABHD3 abhydrolase domain containing 3
AGO3 argonaute RISC catalytic component 3
AOAH acyloxyacyl hydrolase (neutrophil)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBS1 Bardet-Biedl syndrome 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD2 BTB (POZ) domain containing 2
C12ORF43 chromosome 12 open reading frame 43
C14ORF93 chromosome 14 open reading frame 93
CBR4 carbonyl reductase 4
CEP295 centrosomal protein 295kDa
CISH cytokine inducible SH2-containing protein
CLEC2D C-type lectin domain family 2, member D
CXCR2 chemokine (C-X-C motif) receptor 2
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAL4 dynein, axonemal, light chain 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ELP6 elongator acetyltransferase complex subunit 6
FAM127B family with sequence similarity 127, member B
FAM50B family with sequence similarity 50, member B
FAM57A family with sequence similarity 57, member A
FANCF Fanconi anemia, complementation group F
FNBP1L formin binding protein 1-like
FOXN2 forkhead box N2
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H4E histone cluster 1, H4e
HMGA2 high mobility group AT-hook 2
HSPA1L heat shock 70kDa protein 1-like
ICK intestinal cell (MAK-like) kinase
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IMPAD1 inositol monophosphatase domain containing 1
IP6K2 inositol hexakisphosphate kinase 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA1107 KIAA1107
KIN Kin17 DNA and RNA binding protein
KLHL12 kelch-like family member 12
KPTN kaptin (actin binding protein)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMNB1 lamin B1
LRRK1 leucine-rich repeat kinase 1
MFSD6 major facilitator superfamily domain containing 6
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MON1B MON1 secretory trafficking family member B
MPI mannose phosphate isomerase
MTMR12 myotubularin related protein 12
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NABP2 nucleic acid binding protein 2
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPIPB15 nuclear pore complex interacting protein family, member B15
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDE12 phosphodiesterase 12
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PEX6 peroxisomal biogenesis factor 6
PKN1 protein kinase N1
PLA2G12A phospholipase A2, group XIIA
PMCH pro-melanin-concentrating hormone
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RBM42 RNA binding motif protein 42
RECQL4 RecQ protein-like 4
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS19 regulator of G-protein signaling 19
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF25 ring finger protein 25
SCGB2A2 secretoglobin, family 2A, member 2
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SENP7 SUMO1/sentrin specific peptidase 7
SLPI secretory leukocyte peptidase inhibitor
SPRYD7 SPRY domain containing 7
STON1 stonin 1
TAS2R10 taste receptor, type 2, member 10
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEC tec protein tyrosine kinase
TMEM156 transmembrane protein 156
TRAC T cell receptor alpha constant
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TWSG1 twisted gastrulation BMP signaling modulator 1
UBXN8 UBX domain protein 8
ULK1 unc-51 like autophagy activating kinase 1
USB1 U6 snRNA biogenesis 1
VILL villin-like
ZBTB10 zinc finger and BTB domain containing 10
ZBTB3 zinc finger and BTB domain containing 3
ZBTB39 zinc finger and BTB domain containing 39
ZDHHC24 zinc finger, DHHC-type containing 24
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZMYM1 zinc finger, MYM-type 1
ZNF215 zinc finger protein 215
ZNF426 zinc finger protein 426
ZNF74 zinc finger protein 74