dioxybenzone-5699 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the dioxybenzone-5699 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF2 AF4/FMR2 family, member 2
APOE apolipoprotein E
ATF3 activating transcription factor 3
BLVRA biliverdin reductase A
BMP2 bone morphogenetic protein 2
C19ORF66 chromosome 19 open reading frame 66
C5AR2 complement component 5a receptor 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CADM4 cell adhesion molecule 4
CD1E CD1e molecule
CD53 CD53 molecule
CDH8 cadherin 8, type 2
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP250 centrosomal protein 250kDa
CLPS colipase, pancreatic
COL1A1 collagen, type I, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLX4 distal-less homeobox 4
DSCAM Down syndrome cell adhesion molecule
DYM dymeclin
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FHIT fragile histidine triad
FHL1 four and a half LIM domains 1
FLJ11292
GRM8 glutamate receptor, metabotropic 8
HFE hemochromatosis
HIST1H2BN histone cluster 1, H2bn
HLA-DOA major histocompatibility complex, class II, DO alpha
HYAL3 hyaluronoglucosaminidase 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
ING2 inhibitor of growth family, member 2
INHBC inhibin, beta C
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
MAGEA5 melanoma antigen family A5
MAGEC1 melanoma antigen family C1
MATN3 matrilin 3
MED16 mediator complex subunit 16
MED25 mediator complex subunit 25
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDP Norrie disease (pseudoglioma)
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFX1 nuclear transcription factor, X-box binding 1
NPTXR neuronal pentraxin receptor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRN1 neuritin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OR7A10 olfactory receptor, family 7, subfamily A, member 10
OR7C1 olfactory receptor, family 7, subfamily C, member 1
PDE4C phosphodiesterase 4C, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PHACTR1 phosphatase and actin regulator 1
PHF7 PHD finger protein 7
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PLD1 phospholipase D1, phosphatidylcholine-specific
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
RND1 Rho family GTPase 1
RYR1 ryanodine receptor 1 (skeletal)
SDC2 syndecan 2
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SORCS3 sortilin-related VPS10 domain containing receptor 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPX spexin hormone
SYN2 synapsin II
TFR2 transferrin receptor 2
TJAP1 tight junction associated protein 1 (peripheral)
TLR8 toll-like receptor 8
TRIM10 tripartite motif containing 10
TSGA10 testis specific, 10
TSSK2 testis-specific serine kinase 2
ULBP1 UL16 binding protein 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WRNIP1 Werner helicase interacting protein 1
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADGRE5 adhesion G protein-coupled receptor E5
ADORA2B adenosine A2b receptor
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARRB1 arrestin, beta 1
ATP13A2 ATPase type 13A2
BFSP1 beaded filament structural protein 1, filensin
BPGM 2,3-bisphosphoglycerate mutase
C7ORF43 chromosome 7 open reading frame 43
CASD1 CAS1 domain containing 1
CCDC132 coiled-coil domain containing 132
CCDC186 coiled-coil domain containing 186
CDK3 cyclin-dependent kinase 3
CEP85 centrosomal protein 85kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHAF1B chromatin assembly factor 1, subunit B (p60)
CIR1 corepressor interacting with RBPJ, 1
CLGN calmegin
CRABP1 cellular retinoic acid binding protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DUSP8 dual specificity phosphatase 8
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM169A family with sequence similarity 169, member A
FANCC Fanconi anemia, complementation group C
FBXL2 F-box and leucine-rich repeat protein 2
FCHO1 FCH domain only 1
FLRT3 fibronectin leucine rich transmembrane protein 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLI3 GLI family zinc finger 3
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GSTA4 glutathione S-transferase alpha 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
INSIG2 insulin induced gene 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0895 KIAA0895
KIZ kizuna centrosomal protein
LOC100287590 uncharacterized LOC100287590
LPXN leupaxin
LRRC20 leucine rich repeat containing 20
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MARC1 mitochondrial amidoxime reducing component 1
MATK megakaryocyte-associated tyrosine kinase
MCOLN1 mucolipin 1
MFSD10 major facilitator superfamily domain containing 10
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MPC1 mitochondrial pyruvate carrier 1
MSX1 msh homeobox 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTMR14 myotubularin related protein 14
NKX3-2 NK3 homeobox 2
ODF2 outer dense fiber of sperm tails 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PARD6A par-6 family cell polarity regulator alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POM121 POM121 transmembrane nucleoporin
POMZP3 POM121 and ZP3 fusion
PYCRL pyrroline-5-carboxylate reductase-like
RCAN3 RCAN family member 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRAGD Ras-related GTP binding D
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCGB2A2 secretoglobin, family 2A, member 2
SH2D4A SH2 domain containing 4A
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STIM1 stromal interaction molecule 1
TBC1D17 TBC1 domain family, member 17
TCTA T-cell leukemia translocation altered
TLN1 talin 1
TMEM115 transmembrane protein 115
TMEM180 transmembrane protein 180
TMEM19 transmembrane protein 19
TMEM209 transmembrane protein 209
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPST2 tyrosylprotein sulfotransferase 2
TREM1 triggering receptor expressed on myeloid cells 1
TTC33 tetratricopeptide repeat domain 33
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF329 zinc finger protein 329
ZNF350 zinc finger protein 350
ZNF408 zinc finger protein 408
ZNF862 zinc finger protein 862