dioxybenzone-6478 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dioxybenzone-6478 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
AGER advanced glycosylation end product-specific receptor
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANKRD7 ankyrin repeat domain 7
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
CASR calcium-sensing receptor
CCDC181 coiled-coil domain containing 181
CD101 CD101 molecule
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CFAP69 cilia and flagella associated protein 69
CLEC2B C-type lectin domain family 2, member B
CLTA clathrin, light chain A
CPNE7 copine VII
CSPP1 centrosome and spindle pole associated protein 1
CTRC chymotrypsin C (caldecrin)
CYLD cylindromatosis (turban tumor syndrome)
CYSLTR1 cysteinyl leukotriene receptor 1
DENND2A DENN/MADD domain containing 2A
DFNB31 deafness, autosomal recessive 31
DGCR8 DGCR8 microprocessor complex subunit
DOK2 docking protein 2, 56kDa
DUOX2 dual oxidase 2
DUSP10 dual specificity phosphatase 10
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ERN1 endoplasmic reticulum to nucleus signaling 1
ERO1LB ERO1-like beta (S. cerevisiae)
ETV7 ets variant 7
FAIM2 Fas apoptotic inhibitory molecule 2
FGB fibrinogen beta chain
GJB3 gap junction protein, beta 3, 31kDa
GPR21 G protein-coupled receptor 21
HDAC5 histone deacetylase 5
HFE hemochromatosis
HIST1H2BL histone cluster 1, H2bl
HNF4A hepatocyte nuclear factor 4, alpha
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ING1 inhibitor of growth family, member 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM5C lysine (K)-specific demethylase 5C
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT9 keratin 9, type I
LUZP4 leucine zipper protein 4
MAPK8 mitogen-activated protein kinase 8
MMP11 matrix metallopeptidase 11
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NXF2 nuclear RNA export factor 2
OASL 2'-5'-oligoadenylate synthetase-like
OSBPL10 oxysterol binding protein-like 10
OSMR oncostatin M receptor
PCDHB13 protocadherin beta 13
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDZD2 PDZ domain containing 2
PEG3 paternally expressed 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKCE protein kinase C, epsilon
RAB11B RAB11B, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RETN resistin
RNF122 ring finger protein 122
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAPER S-phase cyclin A-associated protein in the ER
SEC24D SEC24 family member D
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMAD1 SMAD family member 1
SNAP25 synaptosomal-associated protein, 25kDa
SOS1 son of sevenless homolog 1 (Drosophila)
SS18 synovial sarcoma translocation, chromosome 18
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SUGP1 SURP and G patch domain containing 1
TBC1D17 TBC1 domain family, member 17
TDRD12 tudor domain containing 12
TEX40 testis expressed 40
TLX2 T-cell leukemia homeobox 2
TRBC1 T cell receptor beta constant 1
TRIB2 tribbles pseudokinase 2
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC38 tetratricopeptide repeat domain 38
TUBA4B tubulin, alpha 4b
UNC93A unc-93 homolog A (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WDFY3 WD repeat and FYVE domain containing 3
WNK1 WNK lysine deficient protein kinase 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABI3BP ABI family, member 3 (NESH) binding protein
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTL8 actin-like 8
AMH anti-Mullerian hormone
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOD apolipoprotein D
ARMC6 armadillo repeat containing 6
ASPN asporin
ATAD5 ATPase family, AAA domain containing 5
BAG4 BCL2-associated athanogene 4
BCAS1 breast carcinoma amplified sequence 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEX4 brain expressed, X-linked 4
C1ORF21 chromosome 1 open reading frame 21
CAPN5 calpain 5
CCDC9 coiled-coil domain containing 9
CHML choroideremia-like (Rab escort protein 2)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCF1 cardiotrophin-like cytokine factor 1
CLCN6 chloride channel, voltage-sensitive 6
CLDND1 claudin domain containing 1
CNN2 calponin 2
CTNNBL1 catenin, beta like 1
CXADR coxsackie virus and adenovirus receptor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EGFL7 EGF-like-domain, multiple 7
F2R coagulation factor II (thrombin) receptor
FKBP1B FK506 binding protein 1B, 12.6 kDa
GALK1 galactokinase 1
GEMIN8 gem (nuclear organelle) associated protein 8
GID4 GID complex subunit 4
GRPR gastrin-releasing peptide receptor
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1E histone cluster 1, H1e
HOXC10 homeobox C10
HOXC5 homeobox C5
IL12RB1 interleukin 12 receptor, beta 1
INCENP inner centromere protein antigens 135/155kDa
IP6K1 inositol hexakisphosphate kinase 1
IPO8 importin 8
ITPKC inositol-trisphosphate 3-kinase C
JMJD4 jumonji domain containing 4
KIAA0895 KIAA0895
KRT13 keratin 13, type I
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC729164 hCG1732469
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MATK megakaryocyte-associated tyrosine kinase
MBNL3 muscleblind-like splicing regulator 3
MED18 mediator complex subunit 18
MED31 mediator complex subunit 31
MNS1 meiosis-specific nuclear structural 1
MXD3 MAX dimerization protein 3
NCALD neurocalcin delta
NCSTN nicastrin
NIPAL2 NIPA-like domain containing 2
NPR3 natriuretic peptide receptor 3
NRSN2 neurensin 2
OVGP1 oviductal glycoprotein 1, 120kDa
PCDHB8 protocadherin beta 8
PGBD5 piggyBac transposable element derived 5
PLIN3 perilipin 3
PPL periplakin
PRPH peripherin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP32 ribosomal protein L23a pseudogene 32
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SFRP5 secreted frizzled-related protein 5
SLC17A2 solute carrier family 17, member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SLMO1 slowmo homolog 1 (Drosophila)
SMTN smoothelin
STRA6 stimulated by retinoic acid 6
STX5 syntaxin 5
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D2 TBC1 domain family, member 2
TESC tescalcin
TMEM19 transmembrane protein 19
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGF VGF nerve growth factor inducible
VLDLR very low density lipoprotein receptor
ZNF324 zinc finger protein 324
ZNF35 zinc finger protein 35
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF573 zinc finger protein 573
ZNF768 zinc finger protein 768
ZSWIM1 zinc finger, SWIM-type containing 1