diperodon-1575 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the diperodon-1575 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACOT11 acyl-CoA thioesterase 11
API5 apoptosis inhibitor 5
ARID1A AT rich interactive domain 1A (SWI-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BBX bobby sox homolog (Drosophila)
BTN2A1 butyrophilin, subfamily 2, member A1
CANT1 calcium activated nucleotidase 1
CASP4 caspase 4, apoptosis-related cysteine peptidase
CAST calpastatin
CBY1 chibby homolog 1 (Drosophila)
CCDC64 coiled-coil domain containing 64
CDC25C cell division cycle 25C
CDK19 cyclin-dependent kinase 19
CENPI centromere protein I
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHD1L chromodomain helicase DNA binding protein 1-like
CHKA choline kinase alpha
CLK1 CDC-like kinase 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CYLD cylindromatosis (turban tumor syndrome)
DBF4B DBF4 zinc finger B
DEAF1 DEAF1 transcription factor
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIDO1 death inducer-obliterator 1
DRG2 developmentally regulated GTP binding protein 2
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
EXD2 exonuclease 3'-5' domain containing 2
EXOC5 exocyst complex component 5
EXOSC2 exosome component 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GJB1 gap junction protein, beta 1, 32kDa
GLI3 GLI family zinc finger 3
GMCL1 germ cell-less, spermatogenesis associated 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNS glucosamine (N-acetyl)-6-sulfatase
GOLM1 golgi membrane protein 1
GPSM2 G-protein signaling modulator 2
GRK6 G protein-coupled receptor kinase 6
HCAR3 hydroxycarboxylic acid receptor 3
HFE hemochromatosis
HIST1H2BD histone cluster 1, H2bd
HLA-F major histocompatibility complex, class I, F
HOXC11 homeobox C11
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KDM5A lysine (K)-specific demethylase 5A
KIFC1 kinesin family member C1
KLC1 kinesin light chain 1
LMAN2L lectin, mannose-binding 2-like
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK13 mitogen-activated protein kinase 13
MBD3 methyl-CpG binding domain protein 3
MBOAT7 membrane bound O-acyltransferase domain containing 7
METTL13 methyltransferase like 13
MPZ myelin protein zero
N4BP1 NEDD4 binding protein 1
N4BP2L2 NEDD4 binding protein 2-like 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NEFH neurofilament, heavy polypeptide
NIPBL Nipped-B homolog (Drosophila)
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OSBP oxysterol binding protein
PAX1 paired box 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCD2 programmed cell death 2
PIEZO1 piezo-type mechanosensitive ion channel component 1
PTAFR platelet-activating factor receptor
RANBP3 RAN binding protein 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIN1 Ras and Rab interactor 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC23IP SEC23 interacting protein
SH3BP2 SH3-domain binding protein 2
SIDT2 SID1 transmembrane family, member 2
SIRT6 sirtuin 6
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC35E3 solute carrier family 35, member E3
SMG5 SMG5 nonsense mediated mRNA decay factor
SPN sialophorin
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TCF4 transcription factor 4
TMBIM1 transmembrane BAX inhibitor motif containing 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPI1 triosephosphate isomerase 1
TRD T cell receptor delta locus
TSPYL2 TSPY-like 2
UBL3 ubiquitin-like 3
USP10 ubiquitin specific peptidase 10
USP20 ubiquitin specific peptidase 20
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF280D zinc finger protein 280D
ZNF350 zinc finger protein 350

decreased expression

Symbol Name
ABHD11 abhydrolase domain containing 11
ACOT8 acyl-CoA thioesterase 8
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALS2CL ALS2 C-terminal like
ANKRD28 ankyrin repeat domain 28
APOBR apolipoprotein B receptor
BBC3 BCL2 binding component 3
CA9 carbonic anhydrase IX
CAPG capping protein (actin filament), gelsolin-like
CAPN1 calpain 1, (mu/I) large subunit
CCDC25 coiled-coil domain containing 25
CCDC88C coiled-coil domain containing 88C
CD82 CD82 molecule
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CEND1 cell cycle exit and neuronal differentiation 1
CEP170B centrosomal protein 170B
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIC capicua transcriptional repressor
CLDN15 claudin 15
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTD2 cyclin N-terminal domain containing 2
CPSF3L cleavage and polyadenylation specific factor 3-like
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DENND1C DENN/MADD domain containing 1C
DMBT1 deleted in malignant brain tumors 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DPP3 dipeptidyl-peptidase 3
DRD5 dopamine receptor D5
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELMO1 engulfment and cell motility 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPM2AIP1 EPM2A (laforin) interacting protein 1
ERO1L ERO1-like (S. cerevisiae)
EXD3 exonuclease 3'-5' domain containing 3
EXOSC10 exosome component 10
FGL1 fibrinogen-like 1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTA4 glutathione S-transferase alpha 4
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2IRD1 GTF2I repeat domain containing 1
HSPA4L heat shock 70kDa protein 4-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
JUNB jun B proto-oncogene
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KLHL21 kelch-like family member 21
L2HGDH L-2-hydroxyglutarate dehydrogenase
LYPLA2P1 lysophospholipase II pseudogene 1
LYZ lysozyme
MAP1S microtubule-associated protein 1S
MAPK10 mitogen-activated protein kinase 10
MBIP MAP3K12 binding inhibitory protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MLPH melanophilin
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPV17 MpV17 mitochondrial inner membrane protein
MRPL52 mitochondrial ribosomal protein L52
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NECAB3 N-terminal EF-hand calcium binding protein 3
NHEJ1 nonhomologous end-joining factor 1
NOTCH1 notch 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHGB5 protocadherin gamma subfamily B, 5
PLCD1 phospholipase C, delta 1
POLE polymerase (DNA directed), epsilon, catalytic subunit
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAD9A RAD9 homolog A (S. pombe)
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD1B SET domain containing 1B
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLN sarcolipin
SNX15 sorting nexin 15
SPEF1 sperm flagellar 1
SPX spexin hormone
TCTA T-cell leukemia translocation altered
TERT telomerase reverse transcriptase
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TJP2 tight junction protein 2
TMED1 transmembrane emp24 protein transport domain containing 1
TOE1 target of EGR1, member 1 (nuclear)
TP53BP1 tumor protein p53 binding protein 1
TRIM22 tripartite motif containing 22
TSPAN32 tetraspanin 32
UBIAD1 UbiA prenyltransferase domain containing 1
VSIG4 V-set and immunoglobulin domain containing 4
WRAP73 WD repeat containing, antisense to TP73
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB48 zinc finger and BTB domain containing 48
ZMYM3 zinc finger, MYM-type 3
ZNF282 zinc finger protein 282