| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the diphenhydramine-7318 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM17 | ADAM metallopeptidase domain 17 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| AVPR1A | arginine vasopressin receptor 1A |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRD1 | bromodomain containing 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CALD1 | caldesmon 1 |
| CCDC85B | coiled-coil domain containing 85B |
| CD52 | CD52 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| DIDO1 | death inducer-obliterator 1 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DOCK9 | dedicator of cytokinesis 9 |
| DXO | decapping exoribonuclease |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| EN2 | engrailed homeobox 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPHB2 | EPH receptor B2 |
| EPHB4 | EPH receptor B4 |
| ETV6 | ets variant 6 |
| FAM174B | family with sequence similarity 174, member B |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FLJ11292 | |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPR107 | G protein-coupled receptor 107 |
| GPR135 | G protein-coupled receptor 135 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HNF1A | HNF1 homeobox A |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| JUND | jun D proto-oncogene |
| KAZN | kazrin, periplakin interacting protein |
| KIAA1109 | KIAA1109 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAPK3 | mitogen-activated protein kinase 3 |
| METTL7A | methyltransferase like 7A |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCOA2 | nuclear receptor coactivator 2 |
| NF2 | neurofibromin 2 (merlin) |
| NMT2 | N-myristoyltransferase 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM3 | PDZ and LIM domain 3 |
| PHF7 | PHD finger protein 7 |
| PITX1 | paired-like homeodomain 1 |
| PKP3 | plakophilin 3 |
| POU3F1 | POU class 3 homeobox 1 |
| PRAF2 | PRA1 domain family, member 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PURG | purine-rich element binding protein G |
| RAB25 | RAB25, member RAS oncogene family |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RGS5 | regulator of G-protein signaling 5 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC39A9 | solute carrier family 39, member 9 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPHK2 | sphingosine kinase 2 |
| SQSTM1 | sequestosome 1 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STK17B | serine/threonine kinase 17b |
| STK38 | serine/threonine kinase 38 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBX1 | T-box 1 |
| TRIM3 | tripartite motif containing 3 |
| UBQLN4 | ubiquilin 4 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| Symbol | Name |
|---|---|
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CST4 | cystatin S |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| E2F6 | E2F transcription factor 6 |
| EGF | epidermal growth factor |
| EHD3 | EH-domain containing 3 |
| EPN3 | epsin 3 |
| FANCC | Fanconi anemia, complementation group C |
| FANCF | Fanconi anemia, complementation group F |
| FBXO2 | F-box protein 2 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FOXJ2 | forkhead box J2 |
| FPGS | folylpolyglutamate synthase |
| FZD3 | frizzled class receptor 3 |
| GLCE | glucuronic acid epimerase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPALPP1 | GPALPP motifs containing 1 |
| HHLA3 | HERV-H LTR-associating 3 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IL11RA | interleukin 11 receptor, alpha |
| IL33 | interleukin 33 |
| IRF6 | interferon regulatory factor 6 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| LMCD1 | LIM and cysteine-rich domains 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL16 | methyltransferase like 16 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MX1 | MX dynamin-like GTPase 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NDRG4 | NDRG family member 4 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OCLN | occludin |
| ODF2 | outer dense fiber of sperm tails 2 |
| OTUD3 | OTU deubiquitinase 3 |
| PALMD | palmdelphin |
| PCBP4 | poly(rC) binding protein 4 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POLM | polymerase (DNA directed), mu |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RWDD3 | RWD domain containing 3 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STAR | steroidogenic acute regulatory protein |
| STX18 | syntaxin 18 |
| TAGLN3 | transgelin 3 |
| TBC1D17 | TBC1 domain family, member 17 |
| TCTN2 | tectonic family member 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM5 | tripartite motif containing 5 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UNC13B | unc-13 homolog B (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP6NL | USP6 N-terminal like |
| VWA1 | von Willebrand factor A domain containing 1 |
| XK | X-linked Kx blood group |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF34 | zinc finger protein 34 |
| ZNF711 | zinc finger protein 711 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |