diphenylpyraline-3640 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the diphenylpyraline-3640 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEBP1 AE binding protein 1
ANK2 ankyrin 2, neuronal
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATAT1 alpha tubulin acetyltransferase 1
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BEST2 bestrophin 2
BMP8B bone morphogenetic protein 8b
BTN3A1 butyrophilin, subfamily 3, member A1
C4BPA complement component 4 binding protein, alpha
C6 complement component 6
CCL19 chemokine (C-C motif) ligand 19
CD79B CD79b molecule, immunoglobulin-associated beta
CDC14B cell division cycle 14B
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CETN1 centrin, EF-hand protein, 1
COL6A2 collagen, type VI, alpha 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAPK2 death-associated protein kinase 2
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FBN1 fibrillin 1
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
FOLR2 folate receptor 2 (fetal)
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GFER growth factor, augmenter of liver regeneration
GPR135 G protein-coupled receptor 135
GPR37L1 G protein-coupled receptor 37 like 1
HAO2 hydroxyacid oxidase 2 (long chain)
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HIF3A hypoxia inducible factor 3, alpha subunit
HIST1H2BN histone cluster 1, H2bn
HYAL3 hyaluronoglucosaminidase 3
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIAA0226L KIAA0226-like
KIAA1644 KIAA1644
KIF5A kinesin family member 5A
KLHL29 kelch-like family member 29
LENEP lens epithelial protein
LOC440895 two pore channel 3 pseudogene
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARK4 MAP/microtubule affinity-regulating kinase 4
MIA melanoma inhibitory activity
MKL1 megakaryoblastic leukemia (translocation) 1
MOGAT2 monoacylglycerol O-acyltransferase 2
NDRG2 NDRG family member 2
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NUMA1 nuclear mitotic apparatus protein 1
OGFR opioid growth factor receptor
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE10A phosphodiesterase 10A
PDE3A phosphodiesterase 3A, cGMP-inhibited
PER1 period circadian clock 1
PHF1 PHD finger protein 1
PKNOX1 PBX/knotted 1 homeobox 1
PKP1 plakophilin 1
PPARA peroxisome proliferator-activated receptor alpha
RAB2A RAB2A, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RAVER2 ribonucleoprotein, PTB-binding 2
RORC RAR-related orphan receptor C
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RUFY3 RUN and FYVE domain containing 3
SAMD4A sterile alpha motif domain containing 4A
SASH3 SAM and SH3 domain containing 3
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGK2 serum/glucocorticoid regulated kinase 2
SH3BP2 SH3-domain binding protein 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOGA1 suppressor of glucose, autophagy associated 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SRSF5 serine/arginine-rich splicing factor 5
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STOM stomatin
TBC1D2 TBC1 domain family, member 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCEAL2 transcription elongation factor A (SII)-like 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCL1A T-cell leukemia/lymphoma 1A
TGM4 transglutaminase 4
TREM2 triggering receptor expressed on myeloid cells 2
TRH thyrotropin-releasing hormone
WDR62 WD repeat domain 62
WNT10B wingless-type MMTV integration site family, member 10B
WNT6 wingless-type MMTV integration site family, member 6
XYLB xylulokinase homolog (H. influenzae)
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM15 ADAM metallopeptidase domain 15
ADAP2 ArfGAP with dual PH domains 2
AIRE autoimmune regulator
AKAP5 A kinase (PRKA) anchor protein 5
AMT aminomethyltransferase
ARHGAP4 Rho GTPase activating protein 4
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF21 chromosome 11 open reading frame 21
C19ORF73 chromosome 19 open reading frame 73
C5AR1 complement component 5a receptor 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC71 coiled-coil domain containing 71
CCNO cyclin O
CD82 CD82 molecule
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CEND1 cell cycle exit and neuronal differentiation 1
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLDN11 claudin 11
CNPY4 canopy FGF signaling regulator 4
CPA4 carboxypeptidase A4
CRABP1 cellular retinoic acid binding protein 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRY2 cryptochrome circadian clock 2
CTRL chymotrypsin-like
CUZD1 CUB and zona pellucida-like domains 1
DAO D-amino-acid oxidase
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOK2 docking protein 2, 56kDa
DOK5 docking protein 5
F9 coagulation factor IX
FAM160B2 family with sequence similarity 160, member B2
FAM212B family with sequence similarity 212, member B
FAM76A family with sequence similarity 76, member A
FBXL8 F-box and leucine-rich repeat protein 8
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP10 FK506 binding protein 10, 65 kDa
FRMD1 FERM domain containing 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC7 histone deacetylase 7
HIST1H2AK histone cluster 1, H2ak
HIST1H2BJ histone cluster 1, H2bj
HIST1H3F histone cluster 1, H3f
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL12RB1 interleukin 12 receptor, beta 1
IL18 interleukin 18
IL2RB interleukin 2 receptor, beta
ITGA10 integrin, alpha 10
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCTD17 potassium channel tetramerization domain containing 17
KIAA1107 KIAA1107
KRT9 keratin 9, type I
LAX1 lymphocyte transmembrane adaptor 1
LRRC61 leucine rich repeat containing 61
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGEA5 melanoma antigen family A5
MCOLN1 mucolipin 1
MYO1F myosin IF
NPY4R neuropeptide Y receptor Y4
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PGBD5 piggyBac transposable element derived 5
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRKCE protein kinase C, epsilon
PWAR5 Prader Willi/Angelman region RNA 5
RAB40C RAB40C, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF208 ring finger protein 208
RPL10L ribosomal protein L10-like
SDS serine dehydratase
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC16A4 solute carrier family 16, member 4
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLN sarcolipin
SLPI secretory leukocyte peptidase inhibitor
TFDP3 transcription factor Dp family, member 3
TLR2 toll-like receptor 2
TMPRSS4 transmembrane protease, serine 4
TYRP1 tyrosinase-related protein 1
XYLT2 xylosyltransferase II
ZNF280A zinc finger protein 280A
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639
ZNF816 zinc finger protein 816
ZSCAN2 zinc finger and SCAN domain containing 2