diphenylpyraline-3743 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the diphenylpyraline-3743 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ARTN artemin
BBC3 BCL2 binding component 3
BCAS3 breast carcinoma amplified sequence 3
BMP7 bone morphogenetic protein 7
BTNL3 butyrophilin-like 3
CALCR calcitonin receptor
CD22 CD22 molecule
CD52 CD52 molecule
CDC14B cell division cycle 14B
CLCN4 chloride channel, voltage-sensitive 4
CLCN7 chloride channel, voltage-sensitive 7
CLDN11 claudin 11
COL1A2 collagen, type I, alpha 2
COPE coatomer protein complex, subunit epsilon
CREB3L1 cAMP responsive element binding protein 3-like 1
CRHR2 corticotropin releasing hormone receptor 2
CRLF1 cytokine receptor-like factor 1
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CST4 cystatin S
CXCR4 chemokine (C-X-C motif) receptor 4
DMWD dystrophia myotonica, WD repeat containing
EGR1 early growth response 1
ERO1LB ERO1-like beta (S. cerevisiae)
FCAR Fc fragment of IgA receptor
FER fer (fps/fes related) tyrosine kinase
FLJ22184
FOXO4 forkhead box O4
FUBP1 far upstream element (FUSE) binding protein 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GDF2 growth differentiation factor 2
GLB1L2 galactosidase, beta 1-like 2
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR15 G protein-coupled receptor 15
GSPT1 G1 to S phase transition 1
HAP1 huntingtin-associated protein 1
HHAT hedgehog acyltransferase
HOXB5 homeobox B5
ICK intestinal cell (MAK-like) kinase
IL1RN interleukin 1 receptor antagonist
IL32 interleukin 32
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNIP1 Kv channel interacting protein 1
KIAA1109 KIAA1109
KRTAP9-9 keratin associated protein 9-9
LIMK2 LIM domain kinase 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MEF2D myocyte enhancer factor 2D
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MYEF2 myelin expression factor 2
NPPA natriuretic peptide A
NPTX1 neuronal pentraxin I
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRP1 neuropilin 1
OPCML opioid binding protein/cell adhesion molecule-like
OSBP2 oxysterol binding protein 2
PCDH7 protocadherin 7
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGK2 phosphoglycerate kinase 2
PGM5 phosphoglucomutase 5
PHOX2B paired-like homeobox 2b
PML promyelocytic leukemia
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM2 PR domain containing 2, with ZNF domain
PRDX2 peroxiredoxin 2
PRKCE protein kinase C, epsilon
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAD23B RAD23 homolog B (S. cerevisiae)
RPL18 ribosomal protein L18
RUNX1 runt-related transcription factor 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SRRT serrate, RNA effector molecule
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAB2 stabilin 2
SYN3 synapsin III
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK2 TAO kinase 2
TBK1 TANK-binding kinase 1
TET3 tet methylcytosine dioxygenase 3
TGFA transforming growth factor, alpha
THAP3 THAP domain containing, apoptosis associated protein 3
TJAP1 tight junction associated protein 1 (peripheral)
TJP3 tight junction protein 3
TRIM23 tripartite motif containing 23
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSC22D2 TSC22 domain family, member 2
TUBA3C tubulin, alpha 3c
VPS9D1 VPS9 domain containing 1
WIZ widely interspaced zinc finger motifs
WNT3 wingless-type MMTV integration site family, member 3
ZBTB18 zinc finger and BTB domain containing 18
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAP2 ArfGAP with dual PH domains 2
AHSG alpha-2-HS-glycoprotein
AK5 adenylate kinase 5
APH1B APH1B gamma secretase subunit
ARHGAP24 Rho GTPase activating protein 24
BDKRB1 bradykinin receptor B1
BEND5 BEN domain containing 5
C1ORF54 chromosome 1 open reading frame 54
C1QTNF3 C1q and tumor necrosis factor related protein 3
C3 complement component 3
C6ORF47 chromosome 6 open reading frame 47
C8ORF44 chromosome 8 open reading frame 44
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC7 coiled-coil domain containing 7
CD82 CD82 molecule
CDH19 cadherin 19, type 2
CDK6 cyclin-dependent kinase 6
CEP41 centrosomal protein 41kDa
CLSTN3 calsyntenin 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CORO7 coronin 7
DIO3 deiodinase, iodothyronine, type III
DNAH7 dynein, axonemal, heavy chain 7
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELMO3 engulfment and cell motility 3
EPPK1 epiplakin 1
EXD3 exonuclease 3'-5' domain containing 3
FAM189A2 family with sequence similarity 189, member A2
FBXL7 F-box and leucine-rich repeat protein 7
FLJ21369 uncharacterized protein FLJ21369
FRMD1 FERM domain containing 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAO2 hydroxyacid oxidase 2 (long chain)
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H2AM histone cluster 1, H2am
HIST1H3C histone cluster 1, H3c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXA7 homeobox A7
HOXC11 homeobox C11
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IDI2-AS1 IDI2 antisense RNA 1
IL33 interleukin 33
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LINC00312 long intergenic non-protein coding RNA 312
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP2 microtubule-associated protein 2
MBNL3 muscleblind-like splicing regulator 3
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRPL52 mitochondrial ribosomal protein L52
NDP Norrie disease (pseudoglioma)
NELL2 NEL-like 2 (chicken)
NKX3-2 NK3 homeobox 2
NPIPB15 nuclear pore complex interacting protein family, member B15
PADI1 peptidyl arginine deiminase, type I
PAQR5 progestin and adipoQ receptor family member V
PARD6A par-6 family cell polarity regulator alpha
PCBP3 poly(rC) binding protein 3
PCDHA9 protocadherin alpha 9
PGLYRP4 peptidoglycan recognition protein 4
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLD2 phospholipase D2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRAMEF10 PRAME family member 10
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB30 RAB30, member RAS oncogene family
RGCC regulator of cell cycle
S100A3 S100 calcium binding protein A3
SCIN scinderin
SGK2 serum/glucocorticoid regulated kinase 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SP1 Sp1 transcription factor
STEAP4 STEAP family member 4
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
THBS3 thrombospondin 3
TMEM74B transmembrane protein 74B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAC T cell receptor alpha constant
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP19 ubiquitin specific peptidase 19
USP6 ubiquitin specific peptidase 6
VGLL3 vestigial-like family member 3
WDR62 WD repeat domain 62
ZNF268 zinc finger protein 268
ZNF529 zinc finger protein 529
ZNF639 zinc finger protein 639
ZNF749 zinc finger protein 749