diphenylpyraline-4765 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the diphenylpyraline-4765 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADGRB1 adhesion G protein-coupled receptor B1
ADGRE1 adhesion G protein-coupled receptor E1
AKT3 v-akt murine thymoma viral oncogene homolog 3
AQP3 aquaporin 3 (Gill blood group)
ART1 ADP-ribosyltransferase 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
CALB2 calbindin 2
CALCR calcitonin receptor
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAPN10 calpain 10
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD209 CD209 molecule
CD48 CD48 molecule
CDK19 cyclin-dependent kinase 19
CEMP1 cementum protein 1
COL1A1 collagen, type I, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYHR1 cysteine/histidine-rich 1
DAGLA diacylglycerol lipase, alpha
DPF1 D4, zinc and double PHD fingers family 1
DXO decapping exoribonuclease
ELAVL3 ELAV like neuron-specific RNA binding protein 3
FGD1 FYVE, RhoGEF and PH domain containing 1
GFI1 growth factor independent 1 transcription repressor
GGT1 gamma-glutamyltransferase 1
GLB1L galactosidase, beta 1-like
GPR176 G protein-coupled receptor 176
GRB10 growth factor receptor-bound protein 10
GRM7 glutamate receptor, metabotropic 7
HBP1 HMG-box transcription factor 1
HDC histidine decarboxylase
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFT27 intraflagellar transport 27
IGF1R insulin-like growth factor 1 receptor
KCNK10 potassium channel, two pore domain subfamily K, member 10
KLF2 Kruppel-like factor 2
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMC2 laminin, gamma 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MALL mal, T-cell differentiation protein-like
MAOB monoamine oxidase B
MARK4 MAP/microtubule affinity-regulating kinase 4
MBD2 methyl-CpG binding domain protein 2
MCAM melanoma cell adhesion molecule
MLN motilin
MST1L macrophage stimulating 1-like
MTMR8 myotubularin related protein 8
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NECAB2 N-terminal EF-hand calcium binding protein 2
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOD1 nucleotide-binding oligomerization domain containing 1
NRF1 nuclear respiratory factor 1
OMD osteomodulin
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OXCT2 3-oxoacid CoA transferase 2
PCDH11Y protocadherin 11 Y-linked
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHOX2B paired-like homeobox 2b
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRDM1 PR domain containing 1, with ZNF domain
PSCA prostate stem cell antigen
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAB6A RAB6A, member RAS oncogene family
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RUSC2 RUN and SH3 domain containing 2
SCAPER S-phase cyclin A-associated protein in the ER
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC2 syndecan 2
SENP7 SUMO1/sentrin specific peptidase 7
SERHL2 serine hydrolase-like 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNRK SNF related kinase
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSX3 synovial sarcoma, X breakpoint 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT5 synaptotagmin V
TCF12 transcription factor 12
TCP11L1 t-complex 11, testis-specific-like 1
THOC5 THO complex 5
TK2 thymidine kinase 2, mitochondrial
TNXB tenascin XB
TPM2 tropomyosin 2 (beta)
TRIM49 tripartite motif containing 49
UNC5B unc-5 homolog B (C. elegans)
ZFAND5 zinc finger, AN1-type domain 5
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTL8 actin-like 8
AGMAT agmatine ureohydrolase (agmatinase)
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATAD5 ATPase family, AAA domain containing 5
C11ORF30 chromosome 11 open reading frame 30
C14ORF79 chromosome 14 open reading frame 79
C2ORF27A chromosome 2 open reading frame 27A
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD8A CD8a molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEL carboxyl ester lipase
CLSTN2 calsyntenin 2
CNGB3 cyclic nucleotide gated channel beta 3
CNR2 cannabinoid receptor 2 (macrophage)
CORT cortistatin
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOCK4 dedicator of cytokinesis 4
DYM dymeclin
ELP6 elongator acetyltransferase complex subunit 6
ELSPBP1 epididymal sperm binding protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLRA1 glycine receptor, alpha 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPC3 glypican 3
GRAMD1C GRAM domain containing 1C
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HCG4 HLA complex group 4 (non-protein coding)
HIRA histone cell cycle regulator
HIST1H2BO histone cluster 1, H2bo
HIST1H3I histone cluster 1, H3i
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IL22 interleukin 22
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD17 potassium channel tetramerization domain containing 17
KDM5C lysine (K)-specific demethylase 5C
KLHL21 kelch-like family member 21
LHX6 LIM homeobox 6
LIG4 ligase IV, DNA, ATP-dependent
LINC01587 long intergenic non-protein coding RNA 1587
MCTP1 multiple C2 domains, transmembrane 1
MEFV Mediterranean fever
MMRN2 multimerin 2
MYLK myosin light chain kinase
NIPAL2 NIPA-like domain containing 2
NLRX1 NLR family member X1
NNAT neuronatin
NOL12 nucleolar protein 12
OLFML2A olfactomedin-like 2A
PCDHA9 protocadherin alpha 9
PDE12 phosphodiesterase 12
PEX26 peroxisomal biogenesis factor 26
PHEX phosphate regulating endopeptidase homolog, X-linked
PLA2G1B phospholipase A2, group IB (pancreas)
PLAT plasminogen activator, tissue
PLD2 phospholipase D2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRSS53 protease, serine, 53
RAB36 RAB36, member RAS oncogene family
RAI2 retinoic acid induced 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHOBTB2 Rho-related BTB domain containing 2
RPL23AP53 ribosomal protein L23a pseudogene 53
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SELL selectin L
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIX1 SIX homeobox 1
SKI SKI proto-oncogene
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMR3A submaxillary gland androgen regulated protein 3A
SNTA1 syntrophin, alpha 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STON1 stonin 1
TIGD6 tigger transposable element derived 6
TMEM120B transmembrane protein 120B
TMEM38B transmembrane protein 38B
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
ZFHX4 zinc finger homeobox 4
ZNF423 zinc finger protein 423