diphenylpyraline-6061 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the diphenylpyraline-6061 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADRA1D adrenoceptor alpha 1D
AMPD3 adenosine monophosphate deaminase 3
ANXA2P1 annexin A2 pseudogene 1
ARHGAP4 Rho GTPase activating protein 4
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL3 ADP-ribosylation factor-like 3
BIN1 bridging integrator 1
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF79 chromosome 14 open reading frame 79
C17ORF53 chromosome 17 open reading frame 53
C1S complement component 1, s subcomponent
C2 complement component 2
CCDC40 coiled-coil domain containing 40
CCDC70 coiled-coil domain containing 70
CD6 CD6 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDRT1 CMT1A duplicated region transcript 1
CEND1 cell cycle exit and neuronal differentiation 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CIZ1 CDKN1A interacting zinc finger protein 1
CLCN7 chloride channel, voltage-sensitive 7
CLEC11A C-type lectin domain family 11, member A
CPNE7 copine VII
CRH corticotropin releasing hormone
DCTN1 dynactin 1
DEPDC5 DEP domain containing 5
DFNB31 deafness, autosomal recessive 31
ECE1 endothelin converting enzyme 1
EPS8L3 EPS8-like 3
EPYC epiphycan
EXPH5 exophilin 5
FRMD1 FERM domain containing 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPER1 G protein-coupled estrogen receptor 1
GPR137 G protein-coupled receptor 137
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFI6 interferon, alpha-inducible protein 6
INHBA inhibin, beta A
IPCEF1 interaction protein for cytohesin exchange factors 1
ITGB7 integrin, beta 7
KCNIP1 Kv channel interacting protein 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCTD17 potassium channel tetramerization domain containing 17
KDM5A lysine (K)-specific demethylase 5A
KIAA1654 KIAA1654 protein
KLHL25 kelch-like family member 25
KRT15 keratin 15, type I
LAMP1 lysosomal-associated membrane protein 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRC2 leucine rich repeat containing 2
MAP2K7 mitogen-activated protein kinase kinase 7
MBD2 methyl-CpG binding domain protein 2
MCAM melanoma cell adhesion molecule
MSMB microseminoprotein, beta-
MTMR8 myotubularin related protein 8
NF2 neurofibromin 2 (merlin)
OPCML opioid binding protein/cell adhesion molecule-like
OR2W1 olfactory receptor, family 2, subfamily W, member 1
PEX26 peroxisomal biogenesis factor 26
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
POFUT2 protein O-fucosyltransferase 2
POLM polymerase (DNA directed), mu
QPCT glutaminyl-peptide cyclotransferase
RASAL2 RAS protein activator like 2
RFPL3 ret finger protein-like 3
RGS7 regulator of G-protein signaling 7
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RTN2 reticulon 2
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SOCS3 suppressor of cytokine signaling 3
SOCS7 suppressor of cytokine signaling 7
SORBS2 sorbin and SH3 domain containing 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSX3 synovial sarcoma, X breakpoint 3
STK24 serine/threonine kinase 24
SYCP1 synaptonemal complex protein 1
TAOK2 TAO kinase 2
TBCD tubulin folding cofactor D
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRA T cell receptor alpha locus
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TTC38 tetratricopeptide repeat domain 38
UCN urocortin
VWA5A von Willebrand factor A domain containing 5A
WASL Wiskott-Aldrich syndrome-like
ZNF224 zinc finger protein 224
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACBD4 acyl-CoA binding domain containing 4
ADGRG2 adhesion G protein-coupled receptor G2
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AUTS2 autism susceptibility candidate 2
C11ORF80 chromosome 11 open reading frame 80
C8ORF44 chromosome 8 open reading frame 44
CAPG capping protein (actin filament), gelsolin-like
CCNO cyclin O
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CFAP69 cilia and flagella associated protein 69
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CRMP1 collapsin response mediator protein 1
CRY2 cryptochrome circadian clock 2
CTSF cathepsin F
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DNM3 dynamin 3
DPF3 D4, zinc and double PHD fingers, family 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EN2 engrailed homeobox 2
ENO3 enolase 3 (beta, muscle)
ERCC5 excision repair cross-complementation group 5
ETV6 ets variant 6
FAM169A family with sequence similarity 169, member A
FAM76A family with sequence similarity 76, member A
FBXO2 F-box protein 2
FKBP10 FK506 binding protein 10, 65 kDa
GID4 GID complex subunit 4
GMPR guanosine monophosphate reductase
GPR21 G protein-coupled receptor 21
GSTP1 glutathione S-transferase pi 1
HAND1 heart and neural crest derivatives expressed 1
HOXC5 homeobox C5
HOXD11 homeobox D11
ICOS inducible T-cell co-stimulator
INO80D INO80 complex subunit D
INSL4 insulin-like 4 (placenta)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMTK2 lemur tyrosine kinase 2
LMX1B LIM homeobox transcription factor 1, beta
LY86 lymphocyte antigen 86
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MUC3A mucin 3A, cell surface associated
NDE1 nudE neurodevelopment protein 1
NEUROD4 neuronal differentiation 4
NPM3 nucleophosmin/nucleoplasmin 3
PDE5A phosphodiesterase 5A, cGMP-specific
PDLIM2 PDZ and LIM domain 2 (mystique)
PODNL1 podocan-like 1
POMT2 protein-O-mannosyltransferase 2
PRKCE protein kinase C, epsilon
QSER1 glutamine and serine rich 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RHBDD3 rhomboid domain containing 3
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RPL10L ribosomal protein L10-like
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC17A2 solute carrier family 17, member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SOAT2 sterol O-acyltransferase 2
SPARCL1 SPARC-like 1 (hevin)
STAB2 stabilin 2
STARD5 StAR-related lipid transfer (START) domain containing 5
TBX19 T-box 19
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TOR4A torsin family 4, member A
TRDMT1 tRNA aspartic acid methyltransferase 1
TWISTNB TWIST neighbor
USB1 U6 snRNA biogenesis 1
VIPR1 vasoactive intestinal peptide receptor 1
VN1R1 vomeronasal 1 receptor 1
VPS9D1 VPS9 domain containing 1
ZBED8 zinc finger, BED-type containing 8
ZBTB44 zinc finger and BTB domain containing 44
ZNF362 zinc finger protein 362
ZNF480 zinc finger protein 480
ZNF532 zinc finger protein 532