diphtheria Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A primary bacterial infectious disease that is characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria can be restricted to the skin. It is caused by Corynebacterium diphtheriae, an aerobic Gram-positive bacterium. Diphtheria toxin spreads through the bloodstream and can lead to potentially life-threatening complications that affect other organs of the body, such as the heart and kidneys. (Experimental Factor Ontology, EFO_0005549)
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Genes

8 genes co-occuring with the biological term diphtheria in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
DEFA1 defensin, alpha 1
HBEGF heparin-binding EGF-like growth factor
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IL1A interleukin 1, alpha
PLAUR plasminogen activator, urokinase receptor
PPIA peptidylprolyl isomerase A (cyclophilin A)
TRADD TNFRSF1A-associated via death domain
TXNRD1 thioredoxin reductase 1