dipivefrine-6766 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dipivefrine-6766 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADAM2 ADAM metallopeptidase domain 2
ARHGAP44 Rho GTPase activating protein 44
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BCL2L2 BCL2-like 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA4 carbonic anhydrase IV
CDADC1 cytidine and dCMP deaminase domain containing 1
CFAP69 cilia and flagella associated protein 69
CFLAR CASP8 and FADD-like apoptosis regulator
CHKB choline kinase beta
CLCN7 chloride channel, voltage-sensitive 7
CNOT3 CCR4-NOT transcription complex, subunit 3
COPZ2 coatomer protein complex, subunit zeta 2
CSHL1 chorionic somatomammotropin hormone-like 1
CTAGE5 CTAGE family, member 5
CTBP2 C-terminal binding protein 2
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DCN decorin
DNAH17 dynein, axonemal, heavy chain 17
DOCK6 dedicator of cytokinesis 6
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DRD2 dopamine receptor D2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUSP13 dual specificity phosphatase 13
DUSP9 dual specificity phosphatase 9
ERC2-IT1 ERC2 intronic transcript 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETV7 ets variant 7
FCMR Fc fragment of IgM receptor
FGFR2 fibroblast growth factor receptor 2
FMO6P flavin containing monooxygenase 6 pseudogene
GFI1 growth factor independent 1 transcription repressor
GRIK5 glutamate receptor, ionotropic, kainate 5
HIST1H1T histone cluster 1, H1t
HOXA10 homeobox A10
HOXB6 homeobox B6
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KRT19P2 keratin 19 pseudogene 2
LRP12 low density lipoprotein receptor-related protein 12
MAPT microtubule-associated protein tau
MCF2L MCF.2 cell line derived transforming sequence-like
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP19 matrix metallopeptidase 19
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOP16 NOP16 nucleolar protein
NR2F1 nuclear receptor subfamily 2, group F, member 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PARP12 poly (ADP-ribose) polymerase family, member 12
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE4C phosphodiesterase 4C, cAMP-specific
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGBD5 piggyBac transposable element derived 5
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOX2A paired-like homeobox 2a
PLIN2 perilipin 2
PLK3 polo-like kinase 3
PRDX2 peroxiredoxin 2
RAB6A RAB6A, member RAS oncogene family
RECQL5 RecQ protein-like 5
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
SFRP4 secreted frizzled-related protein 4
SH3BP2 SH3-domain binding protein 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLN sarcolipin
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNPH syntaphilin
SPPL2B signal peptide peptidase like 2B
SSX3 synovial sarcoma, X breakpoint 3
STAB2 stabilin 2
STAT2 signal transducer and activator of transcription 2, 113kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAGLN3 transgelin 3
TDRKH tudor and KH domain containing
TK2 thymidine kinase 2, mitochondrial
TRIM29 tripartite motif containing 29
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPYL2 TSPY-like 2
UBAP1 ubiquitin associated protein 1
USP46 ubiquitin specific peptidase 46
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VASH2 vasohibin 2
WDR33 WD repeat domain 33
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
WSCD1 WSC domain containing 1
ZNF10 zinc finger protein 10
ZNF16 zinc finger protein 16
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACYP2 acylphosphatase 2, muscle type
ADGRG2 adhesion G protein-coupled receptor G2
AFF4 AF4/FMR2 family, member 4
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALPK1 alpha-kinase 1
BAK1 BCL2-antagonist/killer 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
CCDC186 coiled-coil domain containing 186
CCDC69 coiled-coil domain containing 69
CCDC94 coiled-coil domain containing 94
CD82 CD82 molecule
CDK3 cyclin-dependent kinase 3
CENPQ centromere protein Q
CFAP44 cilia and flagella associated protein 44
CGREF1 cell growth regulator with EF-hand domain 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIDEB cell death-inducing DFFA-like effector b
CLDN1 claudin 1
CLDN15 claudin 15
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EAF2 ELL associated factor 2
EDC4 enhancer of mRNA decapping 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ETAA1 Ewing tumor-associated antigen 1
EXD3 exonuclease 3'-5' domain containing 3
FAM131A family with sequence similarity 131, member A
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
GAMT guanidinoacetate N-methyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HLA-J major histocompatibility complex, class I, J (pseudogene)
ICK intestinal cell (MAK-like) kinase
IFI6 interferon, alpha-inducible protein 6
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
IRAK4 interleukin-1 receptor-associated kinase 4
JMJD4 jumonji domain containing 4
JUNB jun B proto-oncogene
KDM5C lysine (K)-specific demethylase 5C
LIG4 ligase IV, DNA, ATP-dependent
LINC00115 long intergenic non-protein coding RNA 115
LRRC20 leucine rich repeat containing 20
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MTERF4 mitochondrial transcription termination factor 4
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NNAT neuronatin
NPM3 nucleophosmin/nucleoplasmin 3
P3H1 prolyl 3-hydroxylase 1
PCDHB3 protocadherin beta 3
PCDHGB5 protocadherin gamma subfamily B, 5
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLD2 phospholipase D2
POLL polymerase (DNA directed), lambda
PPT2 palmitoyl-protein thioesterase 2
PROCR protein C receptor, endothelial
PRR7 proline rich 7 (synaptic)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS16 protease, serine, 16 (thymus)
PTBP2 polypyrimidine tract binding protein 2
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASAL1 RAS protein activator like 1 (GAP1 like)
RIBC2 RIB43A domain with coiled-coils 2
ROM1 retinal outer segment membrane protein 1
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
S100A6 S100 calcium binding protein A6
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLIT2 slit homolog 2 (Drosophila)
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TPCN1 two pore segment channel 1
TRAIP TRAF interacting protein
TRAPPC13 trafficking protein particle complex 13
TRIM5 tripartite motif containing 5
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPAN15 tetraspanin 15
UEVLD UEV and lactate/malate dehyrogenase domains
USP36 ubiquitin specific peptidase 36
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP69B ZFP69 zinc finger protein B
ZNF492 zinc finger protein 492
ZNF623 zinc finger protein 623
ZNF675 zinc finger protein 675
ZNF7 zinc finger protein 7
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816