| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the dipivefrine-7124 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ACACA | acetyl-CoA carboxylase alpha |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASF1A | anti-silencing function 1A histone chaperone |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| BCL2A1 | BCL2-related protein A1 |
| BIN1 | bridging integrator 1 |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| BSPRY | B-box and SPRY domain containing |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CCNO | cyclin O |
| CCPG1 | cell cycle progression 1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CENPJ | centromere protein J |
| CLDN15 | claudin 15 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CORO2A | coronin, actin binding protein, 2A |
| CREM | cAMP responsive element modulator |
| CTH | cystathionine gamma-lyase |
| DENND2A | DENN/MADD domain containing 2A |
| DFNB31 | deafness, autosomal recessive 31 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| EFNA3 | ephrin-A3 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| EPAS1 | endothelial PAS domain protein 1 |
| ERCC1 | excision repair cross-complementation group 1 |
| ERF | Ets2 repressor factor |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GK | glycerol kinase |
| GPATCH1 | G patch domain containing 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR17 | G protein-coupled receptor 17 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IRF6 | interferon regulatory factor 6 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF5C | kinesin family member 5C |
| KLHL36 | kelch-like family member 36 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LAMC2 | laminin, gamma 2 |
| LMBR1L | limb development membrane protein 1-like |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MAP7 | microtubule-associated protein 7 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MCMBP | minichromosome maintenance complex binding protein |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTGES | prostaglandin E synthase |
| PTHLH | parathyroid hormone-like hormone |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB2A | RAB2A, member RAS oncogene family |
| RAB31 | RAB31, member RAS oncogene family |
| RABGAP1 | RAB GTPase activating protein 1 |
| RFK | riboflavin kinase |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPL7 | ribosomal protein L7 |
| S100P | S100 calcium binding protein P |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMOX | spermine oxidase |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| STC1 | stanniocalcin 1 |
| STOM | stomatin |
| TAOK3 | TAO kinase 3 |
| TCF4 | transcription factor 4 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TMC7 | transmembrane channel-like 7 |
| TMEM63A | transmembrane protein 63A |
| TSFM | Ts translation elongation factor, mitochondrial |
| TTC38 | tetratricopeptide repeat domain 38 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| ZNF202 | zinc finger protein 202 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ATP13A2 | ATPase type 13A2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| CAPN5 | calpain 5 |
| CBX7 | chromobox homolog 7 |
| CCDC25 | coiled-coil domain containing 25 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CFAP44 | cilia and flagella associated protein 44 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CTGF | connective tissue growth factor |
| CTSD | cathepsin D |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DGKZ | diacylglycerol kinase, zeta |
| DUS1L | dihydrouridine synthase 1-like (S. cerevisiae) |
| DYSF | dysferlin |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EDC4 | enhancer of mRNA decapping 4 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EIF2B5 | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM102A | family with sequence similarity 102, member A |
| FAM127B | family with sequence similarity 127, member B |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FPGS | folylpolyglutamate synthase |
| GALE | UDP-galactose-4-epimerase |
| GBX2 | gastrulation brain homeobox 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IRF2 | interferon regulatory factor 2 |
| JUNB | jun B proto-oncogene |
| KIAA0556 | KIAA0556 |
| KIFC1 | kinesin family member C1 |
| KLHL3 | kelch-like family member 3 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| KRT15 | keratin 15, type I |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAGEA6 | melanoma antigen family A6 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MKS1 | Meckel syndrome, type 1 |
| MON1B | MON1 secretory trafficking family member B |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| NCS1 | neuronal calcium sensor 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NUBP1 | nucleotide binding protein 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| POLH | polymerase (DNA directed), eta |
| PPL | periplakin |
| PRR3 | proline rich 3 |
| PTX3 | pentraxin 3, long |
| RAB3A | RAB3A, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF121 | ring finger protein 121 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| ROGDI | rogdi homolog (Drosophila) |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SETD1B | SET domain containing 1B |
| SIX1 | SIX homeobox 1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SOX13 | SRY (sex determining region Y)-box 13 |
| STBD1 | starch binding domain 1 |
| STK16 | serine/threonine kinase 16 |
| STRN4 | striatin, calmodulin binding protein 4 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLN1 | talin 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMC5 | transmembrane channel-like 5 |
| TMEM2 | transmembrane protein 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| UBXN2B | UBX domain protein 2B |
| WWC2 | WW and C2 domain containing 2 |
| XPC | xeroderma pigmentosum, complementation group C |
| XYLT2 | xylosyltransferase II |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF426 | zinc finger protein 426 |
| ZNF552 | zinc finger protein 552 |
| ZNF813 | zinc finger protein 813 |
