diprophylline-1689 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the diprophylline-1689 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIF1 allograft inflammatory factor 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ARPIN actin-related protein 2/3 complex inhibitor
ATF6B activating transcription factor 6 beta
ATN1 atrophin 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BBS9 Bardet-Biedl syndrome 9
C17ORF59 chromosome 17 open reading frame 59
CAMKMT calmodulin-lysine N-methyltransferase
CAPN5 calpain 5
CAPN9 calpain 9
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLSPN claspin
DGAT1 diacylglycerol O-acyltransferase 1
DHODH dihydroorotate dehydrogenase (quinone)
EFNA3 ephrin-A3
EMC1 ER membrane protein complex subunit 1
ERCC1 excision repair cross-complementation group 1
ETAA1 Ewing tumor-associated antigen 1
EXO5 exonuclease 5
F5 coagulation factor V (proaccelerin, labile factor)
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H4C histone cluster 1, H4c
IGHM immunoglobulin heavy constant mu
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL17RA interleukin 17 receptor A
IL1A interleukin 1, alpha
ING1 inhibitor of growth family, member 1
INO80D INO80 complex subunit D
IRF5 interferon regulatory factor 5
KCNK10 potassium channel, two pore domain subfamily K, member 10
KDM5A lysine (K)-specific demethylase 5A
KIAA0319L KIAA0319-like
KIAA1456 KIAA1456
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LMO4 LIM domain only 4
LOC399491
LRP2 low density lipoprotein receptor-related protein 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCF2L MCF.2 cell line derived transforming sequence-like
MCM3AP minichromosome maintenance complex component 3 associated protein
MIER2 mesoderm induction early response 1, family member 2
MMP25 matrix metallopeptidase 25
MST1 macrophage stimulating 1
MST1L macrophage stimulating 1-like
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NF1 neurofibromin 1
NFYA nuclear transcription factor Y, alpha
NIPSNAP3B nipsnap homolog 3B (C. elegans)
OSGIN1 oxidative stress induced growth inhibitor 1
PAIP2B poly(A) binding protein interacting protein 2B
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLK3 polo-like kinase 3
PMCH pro-melanin-concentrating hormone
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PRDX2 peroxiredoxin 2
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTPN21 protein tyrosine phosphatase, non-receptor type 21
QKI QKI, KH domain containing, RNA binding
RANBP1 RAN binding protein 1
RANBP3 RAN binding protein 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SCAI suppressor of cancer cell invasion
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNTA1 syntrophin, alpha 1
SP100 SP100 nuclear antigen
SPATA5L1 spermatogenesis associated 5-like 1
SYNJ1 synaptojanin 1
TBL1Y transducin (beta)-like 1, Y-linked
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEX40 testis expressed 40
TMEM63A transmembrane protein 63A
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC9 tetratricopeptide repeat domain 9
VASH2 vasohibin 2
VEGFA vascular endothelial growth factor A
ZBTB43 zinc finger and BTB domain containing 43
ZBTB48 zinc finger and BTB domain containing 48
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF134 zinc finger protein 134
ZNF286A zinc finger protein 286A
ZNF350 zinc finger protein 350

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABHD14A abhydrolase domain containing 14A
ALPK1 alpha-kinase 1
ANO10 anoctamin 10
ARHGAP10 Rho GTPase activating protein 10
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARRB2 arrestin, beta 2
ATAD3A ATPase family, AAA domain containing 3A
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BBS7 Bardet-Biedl syndrome 7
BEX4 brain expressed, X-linked 4
CASZ1 castor zinc finger 1
CCDC88C coiled-coil domain containing 88C
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CENPJ centromere protein J
CEP170B centrosomal protein 170B
CEP72 centrosomal protein 72kDa
CFD complement factor D (adipsin)
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CLCN5 chloride channel, voltage-sensitive 5
CTNNBL1 catenin, beta like 1
DEPTOR DEP domain containing MTOR-interacting protein
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ECHDC3 enoyl CoA hydratase domain containing 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELMO3 engulfment and cell motility 3
ENO2 enolase 2 (gamma, neuronal)
EPHA2 EPH receptor A2
ERO1L ERO1-like (S. cerevisiae)
FBRS fibrosin
FBXL2 F-box and leucine-rich repeat protein 2
FLRT3 fibronectin leucine rich transmembrane protein 3
FSTL3 follistatin-like 3 (secreted glycoprotein)
GMPPA GDP-mannose pyrophosphorylase A
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPR87 G protein-coupled receptor 87
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMOX1 heme oxygenase 1
IFI35 interferon-induced protein 35
IL4R interleukin 4 receptor
KIF13B kinesin family member 13B
KRT13 keratin 13, type I
LAMB3 laminin, beta 3
LIG4 ligase IV, DNA, ATP-dependent
LMCD1 LIM and cysteine-rich domains 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MGC12488
MSL2 male-specific lethal 2 homolog (Drosophila)
NIPAL2 NIPA-like domain containing 2
NRSN2 neurensin 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX26 peroxisomal biogenesis factor 26
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLA2G10 phospholipase A2, group X
PMEPA1 prostate transmembrane protein, androgen induced 1
PROS1 protein S (alpha)
QSER1 glutamine and serine rich 1
RAB3A RAB3A, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RECQL4 RecQ protein-like 4
RGS19 regulator of G-protein signaling 19
RIBC2 RIB43A domain with coiled-coils 2
SIDT1 SID1 transmembrane family, member 1
SLC12A9 solute carrier family 12, member 9
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A40 solute carrier family 25, member 40
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPAG4 sperm associated antigen 4
STK25 serine/threonine kinase 25
TAOK1 TAO kinase 1
TBL3 transducin (beta)-like 3
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM62 transmembrane protein 62
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRAF2 TNF receptor-associated factor 2
TSPAN1 tetraspanin 1
TUBA3D tubulin, alpha 3d
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBXN6 UBX domain protein 6
UBXN8 UBX domain protein 8
WDR4 WD repeat domain 4
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF573 zinc finger protein 573
ZNF7 zinc finger protein 7
ZNF778 zinc finger protein 778
ZNRD1-AS1 ZNRD1 antisense RNA 1