| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the diprophylline-1853 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABR | active BCR-related |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AK1 | adenylate kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDC14A | cell division cycle 14A |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CTC1 | CTS telomere maintenance complex component 1 |
| CYB561 | cytochrome b561 |
| DAPK3 | death-associated protein kinase 3 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EFNA3 | ephrin-A3 |
| EPHB2 | EPH receptor B2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERP44 | endoplasmic reticulum protein 44 |
| FAS | Fas cell surface death receptor |
| FCF1 | FCF1 rRNA-processing protein |
| FKBP5 | FK506 binding protein 5 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| GK3P | glycerol kinase 3 pseudogene |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HK2 | hexokinase 2 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| HSPA4 | heat shock 70kDa protein 4 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| ITGB1BP1 | integrin beta 1 binding protein 1 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KIAA0355 | KIAA0355 |
| KPNB1 | karyopherin (importin) beta 1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAPK3 | mitogen-activated protein kinase 3 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MCOLN1 | mucolipin 1 |
| MED28 | mediator complex subunit 28 |
| MED6 | mediator complex subunit 6 |
| MIS18BP1 | MIS18 binding protein 1 |
| MMP19 | matrix metallopeptidase 19 |
| MST1 | macrophage stimulating 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MZT2B | mitotic spindle organizing protein 2B |
| NCDN | neurochondrin |
| NDE1 | nudE neurodevelopment protein 1 |
| NEFH | neurofilament, heavy polypeptide |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NRP1 | neuropilin 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| POFUT1 | protein O-fucosyltransferase 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPL35A | ribosomal protein L35a |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPS2 | ribosomal protein S2 |
| RYK | receptor-like tyrosine kinase |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SHARPIN | SHANK-associated RH domain interactor |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TPD52 | tumor protein D52 |
| TPI1 | triosephosphate isomerase 1 |
| TPP1 | tripeptidyl peptidase I |
| TRIM36 | tripartite motif containing 36 |
| TSPAN4 | tetraspanin 4 |
| USP46 | ubiquitin specific peptidase 46 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF668 | zinc finger protein 668 |
| ZNF783 | zinc finger family member 783 |
| ZNF816 | zinc finger protein 816 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AEN | apoptosis enhancing nuclease |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BAMBI | BMP and activin membrane-bound inhibitor |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC9 | coiled-coil domain containing 9 |
| CENPT | centromere protein T |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLDN15 | claudin 15 |
| CORO7 | coronin 7 |
| DENND1C | DENN/MADD domain containing 1C |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| DOLK | dolichol kinase |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC8 | excision repair cross-complementation group 8 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR27 | G protein-coupled receptor 27 |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3H | histone cluster 1, H3h |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC157562 | uncharacterized LOC157562 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MANSC1 | MANSC domain containing 1 |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDM4 | MDM4, p53 regulator |
| MED9 | mediator complex subunit 9 |
| METTL1 | methyltransferase like 1 |
| MOB3B | MOB kinase activator 3B |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NARFL | nuclear prelamin A recognition factor-like |
| NINJ2 | ninjurin 2 |
| NKRF | NFKB repressing factor |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PADI2 | peptidyl arginine deiminase, type II |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| POLH | polymerase (DNA directed), eta |
| PRAF2 | PRA1 domain family, member 2 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRR7 | proline rich 7 (synaptic) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTH2R | parathyroid hormone 2 receptor |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RPAP1 | RNA polymerase II associated protein 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCAMP3 | secretory carrier membrane protein 3 |
| SECISBP2 | SECIS binding protein 2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STX5 | syntaxin 5 |
| SURF2 | surfeit 2 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TESK1 | testis-specific kinase 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM134 | transmembrane protein 134 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TOLLIP | toll interacting protein |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM25 | tripartite motif containing 25 |
| TUFT1 | tuftelin 1 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| UPK3A | uroplakin 3A |
| USB1 | U6 snRNA biogenesis 1 |
| WDR33 | WD repeat domain 33 |
| XYLT2 | xylosyltransferase II |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF215 | zinc finger protein 215 |
| ZNF32 | zinc finger protein 32 |
| ZNF506 | zinc finger protein 506 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |