Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the diprophylline-5063 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AGO4 | argonaute RISC catalytic component 4 |
ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
ARHGAP35 | Rho GTPase activating protein 35 |
ARMCX4 | armadillo repeat containing, X-linked 4 |
ASTN2 | astrotactin 2 |
ATF6B | activating transcription factor 6 beta |
ATP10B | ATPase, class V, type 10B |
BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
CCDC85C | coiled-coil domain containing 85C |
CD3D | CD3d molecule, delta (CD3-TCR complex) |
CDC14A | cell division cycle 14A |
CEND1 | cell cycle exit and neuronal differentiation 1 |
CISH | cytokine inducible SH2-containing protein |
CLUAP1 | clusterin associated protein 1 |
COL3A1 | collagen, type III, alpha 1 |
COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
CPZ | carboxypeptidase Z |
CREBZF | CREB/ATF bZIP transcription factor |
CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
DOCK10 | dedicator of cytokinesis 10 |
DOCK9 | dedicator of cytokinesis 9 |
ECM1 | extracellular matrix protein 1 |
EFNB1 | ephrin-B1 |
FAM174B | family with sequence similarity 174, member B |
FBN2 | fibrillin 2 |
FBXO21 | F-box protein 21 |
FGF6 | fibroblast growth factor 6 |
FGL2 | fibrinogen-like 2 |
FKBP10 | FK506 binding protein 10, 65 kDa |
FLT3LG | fms-related tyrosine kinase 3 ligand |
FRMD4A | FERM domain containing 4A |
GAN | gigaxonin |
GDF2 | growth differentiation factor 2 |
GPATCH4 | G patch domain containing 4 |
GRB7 | growth factor receptor-bound protein 7 |
GSK3A | glycogen synthase kinase 3 alpha |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HAP1 | huntingtin-associated protein 1 |
HEATR6 | HEAT repeat containing 6 |
HIP1 | huntingtin interacting protein 1 |
INO80D | INO80 complex subunit D |
KITLG | KIT ligand |
KLHL25 | kelch-like family member 25 |
LAG3 | lymphocyte-activation gene 3 |
LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
MAPK10 | mitogen-activated protein kinase 10 |
MATN3 | matrilin 3 |
MST1 | macrophage stimulating 1 |
MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
MTNR1A | melatonin receptor 1A |
MYO1B | myosin IB |
MYOZ1 | myozenin 1 |
NAV3 | neuron navigator 3 |
PDE4C | phosphodiesterase 4C, cAMP-specific |
PDE4DIP | phosphodiesterase 4D interacting protein |
PER1 | period circadian clock 1 |
PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
PLXNC1 | plexin C1 |
PODXL2 | podocalyxin-like 2 |
PRF1 | perforin 1 (pore forming protein) |
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
PTGDR2 | prostaglandin D2 receptor 2 |
RAB26 | RAB26, member RAS oncogene family |
RAB28 | RAB28, member RAS oncogene family |
RAB3B | RAB3B, member RAS oncogene family |
RASA3 | RAS p21 protein activator 3 |
RPL10 | ribosomal protein L10 |
RXRB | retinoid X receptor, beta |
SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
SENP7 | SUMO1/sentrin specific peptidase 7 |
SIRPA | signal-regulatory protein alpha |
SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
SPATA1 | spermatogenesis associated 1 |
STX16 | syntaxin 16 |
SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
TBC1D22A | TBC1 domain family, member 22A |
TBC1D2B | TBC1 domain family, member 2B |
TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
THBS3 | thrombospondin 3 |
THY1 | Thy-1 cell surface antigen |
TYMS | thymidylate synthetase |
UBOX5 | U-box domain containing 5 |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
VCX2 | variable charge, X-linked 2 |
WIPF1 | WAS/WASL interacting protein family, member 1 |
WNT5B | wingless-type MMTV integration site family, member 5B |
YY1 | YY1 transcription factor |
ZMIZ2 | zinc finger, MIZ-type containing 2 |
ZNF224 | zinc finger protein 224 |
ZNF235 | zinc finger protein 235 |
ZNF3 | zinc finger protein 3 |
ZNF710 | zinc finger protein 710 |
Symbol | Name |
---|---|
ABHD8 | abhydrolase domain containing 8 |
AFAP1 | actin filament associated protein 1 |
AK5 | adenylate kinase 5 |
ALG12 | ALG12, alpha-1,6-mannosyltransferase |
ANKRD7 | ankyrin repeat domain 7 |
APOLD1 | apolipoprotein L domain containing 1 |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
C14ORF93 | chromosome 14 open reading frame 93 |
C22ORF46 | chromosome 22 open reading frame 46 |
CD70 | CD70 molecule |
CENPO | centromere protein O |
CHMP6 | charged multivesicular body protein 6 |
CHRDL1 | chordin-like 1 |
CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
CNN1 | calponin 1, basic, smooth muscle |
CNTNAP1 | contactin associated protein 1 |
CPNE7 | copine VII |
CXORF21 | chromosome X open reading frame 21 |
DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
DLK2 | delta-like 2 homolog (Drosophila) |
DPF3 | D4, zinc and double PHD fingers, family 3 |
DUSP8 | dual specificity phosphatase 8 |
EGF | epidermal growth factor |
ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
ERCC4 | excision repair cross-complementation group 4 |
EXOSC1 | exosome component 1 |
FBXL7 | F-box and leucine-rich repeat protein 7 |
FRS3 | fibroblast growth factor receptor substrate 3 |
GAL3ST4 | galactose-3-O-sulfotransferase 4 |
GPR1 | G protein-coupled receptor 1 |
GUSBP3 | glucuronidase, beta pseudogene 3 |
H2AFJ | H2A histone family, member J |
HIST1H2AM | histone cluster 1, H2am |
HIST1H2BN | histone cluster 1, H2bn |
HIST1H4C | histone cluster 1, H4c |
IL4R | interleukin 4 receptor |
KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
KIAA0894 | KIAA0894 protein |
KIAA0895 | KIAA0895 |
KIAA1456 | KIAA1456 |
KLF13 | Kruppel-like factor 13 |
KRT34 | keratin 34, type I |
LRP3 | low density lipoprotein receptor-related protein 3 |
LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
MAP3K7CL | MAP3K7 C-terminal like |
MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
MED31 | mediator complex subunit 31 |
MFSD12 | major facilitator superfamily domain containing 12 |
MUC2 | mucin 2, oligomeric mucus/gel-forming |
MXD3 | MAX dimerization protein 3 |
MYL9 | myosin, light chain 9, regulatory |
NHEJ1 | nonhomologous end-joining factor 1 |
NOL6 | nucleolar protein 6 (RNA-associated) |
PARD6A | par-6 family cell polarity regulator alpha |
PCDHGB5 | protocadherin gamma subfamily B, 5 |
PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
POLH | polymerase (DNA directed), eta |
PRPH | peripherin |
PRSS53 | protease, serine, 53 |
RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
RGS19 | regulator of G-protein signaling 19 |
RIBC2 | RIB43A domain with coiled-coils 2 |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
RSF1 | remodeling and spacing factor 1 |
SAYSD1 | SAYSVFN motif domain containing 1 |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SEPP1 | selenoprotein P, plasma, 1 |
SLC35F6 | solute carrier family 35, member F6 |
SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
SMAD7 | SMAD family member 7 |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
SNPH | syntaphilin |
STAG3 | stromal antigen 3 |
STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
STARD3 | StAR-related lipid transfer (START) domain containing 3 |
STRA6 | stimulated by retinoic acid 6 |
SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TSC22D4 | TSC22 domain family, member 4 |
TSKU | tsukushi, small leucine rich proteoglycan |
TUBA3C | tubulin, alpha 3c |
USP27X | ubiquitin specific peptidase 27, X-linked |
ZFHX3 | zinc finger homeobox 3 |
ZFP30 | ZFP30 zinc finger protein |
ZFP36 | ZFP36 ring finger protein |
ZNF141 | zinc finger protein 141 |
ZNF276 | zinc finger protein 276 |
ZNF33B | zinc finger protein 33B |
ZNF770 | zinc finger protein 770 |